Search Results - "Chan, Vera"

Interactive Effects of Ocean Acidification, Elevated Temperature, and Reduced Salinity on Early-Life Stages of the Pacific Oyster by Ko, Ginger W. K, Dineshram, R, Campanati, Camilla, Chan, Vera B. S, Havenhand, Jon, Thiyagarajan, Vengatesen

“…Ocean acidification (OA) effects on larvae are partially attributed for the rapidly declining oyster production in the Pacific Northwest region of the United…”
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Th17 cells play a critical role in the development of experimental Sjögren's syndrome by Lin, Xiang, Rui, Ke, Deng, Jun, Tian, Jie, Wang, Xiaohui, Wang, Shengjun, Ko, King-Hung, Jiao, Zhijun, Chan, Vera Sau-Fong, Lau, Chak Sing, Cao, Xuetao, Lu, Liwei

“…Although Th17 cells have been increasingly recognised as an important effector in various autoimmune diseases, their function in the pathogenesis of Sjögren's…”
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Decreased pH does not alter metamorphosis but compromises juvenile calcification of the tube worm Hydroides elegans by Lane, Ackley C., Mukherjee, Joy, Chan, Vera B. S., Thiyagarajan, Vengatesen

“…Using CO 2 perturbation experiments, we examined the pre- and post-settlement growth responses of a dominant biofouling tubeworm ( Hydroides elegans ) to a…”
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DC-SIGN and L-SIGN: the SIGNs for infection by Khoo, Ui-Soon, Chan, Kelvin Y. K., Chan, Vera S. F., Lin, C. L. Steve

“…Two closely related trans -membrane C-type lectins dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin (DC-SIGN or CD209 )…”
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Recapitulating primary immunodeficiencies with expanded potential stem cells: Proof of concept with STAT1 gain of function by Liu, Xueyan, Chan, Vera S.F., Smith, Kenneth G.C., Ming, Chang, Or, Chung Sze, Tsui, Faria T.W., Gao, Bo, Cook, Matthew C., Liu, Pentao, Lau, Chak Sing, Li, Philip Hei

“…[Display omitted] Inborn errors of immunity (IEI) often lack specific disease models and personalized management. Signal transducer and activator of…”
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Cancer cell redirection biomarker discovery using a mutual information approach by Roche, Kimberly, Feltus, F Alex, Park, Jang Pyo, Coissieux, Marie-May, Chang, Chenyan, Chan, Vera B S, Bentires-Alj, Mohamed, Booth, Brian W

“…Introducing tumor-derived cells into normal mammary stem cell niches at a sufficiently high ratio of normal to tumorous cells causes those tumor cells to…”
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Larval and post-larval stages of Pacific oyster (Crassostrea gigas) are resistant to elevated CO2 by Ginger, Ko W K, Vera, Chan B S, R, Dineshram, Dennis, Choi K S, Adela, Li J, Yu, Ziniu, Thiyagarajan, Vengatesen

“…The average pH of surface oceans has decreased by 0.1 unit since industrialization and is expected to decrease by another 0.3-0.7 units before the year 2300…”
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Mechanical robustness of the calcareous tubeworm Hydroides elegans: warming mitigates the adverse effects of ocean acidification by Li, Chaoyi, Meng, Yuan, He, Chong, Chan, Vera B. S., Yao, Haimin, Thiyagarajan, V.

“…Development of antifouling strategies requires knowledge of how fouling organisms would respond to climate change associated environmental stressors. Here, a…”
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MicroRNA-155 Mediates Augmented CD40 Expression in Bone Marrow Derived Plasmacytoid Dendritic Cells in Symptomatic Lupus-Prone NZB/W F1 Mice by Yan, Sheng, Yim, Lok Yan, Tam, Rachel Chun Yee, Chan, Albert, Lu, Liwei, Lau, Chak Sing, Chan, Vera Sau-Fong

“…Systemic lupus erythematosus (SLE) is a chronic multi-organ autoimmune disease characterized by hyperactivated immune responses to self-antigens and persistent…”
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Weakening Mechanisms of the Serpulid Tube in a High-CO2 World by Li, Chaoyi, Chan, Vera B. S, He, Chong, Meng, Yuan, Yao, Haimin, Shih, Kaimin, Thiyagarajan, Vengatesen

“…Many benthic marine organisms produce calcium carbonate (CaCO3) structures for mechanical protection through a biologically controlled calcification process…”
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Ocean acidification reduces hardness and stiffness of the Portuguese oyster shell with impaired microstructure: a hierarchical analysis by Meng, Yuan, Guo, Zhenbin, Fitzer, Susan C., Upadhyay, Abhishek, Chan, Vera B. S., Li, Chaoyi, Cusack, Maggie, Yao, Haimin, Yeung, Kelvin W. K., Thiyagarajan, Vengatesen

“…The rapidly intensifying process of ocean acidification (OA) due to anthropogenic CO2 is not only depleting carbonate ions necessary for calcification but also…”
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MicroRNA-mediated immune regulation in rheumatic diseases by Lam, Ian Kar Yin, Chow, Jia Xin, Lau, Chak Sing, Chan, Vera Sau Fong

“…MicroRNAs (miRNAs) are endogenous small, non-coding RNAs that regulate genome expression at the post-transcriptional level. They are involved in a wide range…”
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Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity by Qiu, Hong, Wu, Haijing, Chan, Vera, Lau, Chak-Sing, Lu, Qianjin

“…T-follicular helper (Tfh) cells are a specialized subset of T cells that provide help to B cells and promote the formation of germinal centers (GCs). Tfh cells…”
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Heterosubtypic Protection Induced by a Live Attenuated Influenza Virus Vaccine Expressing Galactose-α-1,3-Galactose Epitopes in Infected Cells by Yan, Li-Meng, Lau, Sylvia P N, Poh, Chek Meng, Chan, Vera S F, Chan, Michael C W, Peiris, Malik, Poon, Leo L M

“…Anti-galactose-α-1,3-galactose (anti-α-Gal) antibody is naturally expressed at a high level in humans. It constitutes about 1% of immunoglobulins found in…”
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Binding of HIV-1 gp120 to DC-SIGN promotes ASK-1-dependent activation-induced apoptosis of human dendritic cells by Chen, Yongxiong, Hwang, Shiuh-Lin, Chan, Vera S F, Chung, Nancy P Y, Wang, Shu-Rong, Li, Zhongye, Ma, Jing, Lin, Chia-Wei, Hsieh, Ya-Ju, Chang, Kao-Ping, Kung, Sui-Sum, Wu, Yi-Chia, Chu, Cheng-Wei, Tai, Hsiao-Ting, Gao, George F, Zheng, Bojian, Yokoyama, Kazunari K, Austyn, Jonathan M, Lin, Chen-Lung S

“…During disease progression to AIDS, HIV-1 infected individuals become increasingly immunosuppressed and susceptible to opportunistic infections. It has also…”
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The complex role of AIM2 in autoimmune diseases and cancers by Zhu, Huan, Zhao, Ming, Chang, Christopher, Chan, Vera, Lu, Qianjin, Wu, Haijing

“…Absent in melanoma 2 (AIM2) is a novel member of interferon (IFN)‐inducible PYHIN proteins. In innate immune cells, AIM2 servers as a cytoplasmic…”
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Temperature dependent effects of elevated CO2 on shell composition and mechanical properties of Hydroides elegans: insights from a multiple stressor experiment by Chan, Vera B S, Thiyagarajan, Vengatesen, Lu, Xing Wen, Zhang, Tong, Shih, Kaimin

“…The majority of marine benthic invertebrates protect themselves from predators by producing calcareous tubes or shells that have remarkable mechanical…”
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Distinct roles of myeloid and plasmacytoid dendritic cells in systemic lupus erythematosus by Chan, Vera Sau-Fong, Nie, Yin-Jie, Shen, Nan, Yan, Sheng, Mok, Mo-Yin, Lau, Chak-Sing

“…Abstract Dendritic cells (DCs) constitute a heterogeneous population of professional antigen presenting cells which are the initiators and key regulators for…”
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Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes by Tam, Rachel C Y, Lee, Alfred L H, Yang, Wanling, Lau, Chak Sing, Chan, Vera S F

“…Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease with multiple etiological factors. The SLE susceptibility locus on chromosome 16p13…”
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Gold(III) porphyrin complex is more potent than cisplatin in inhibiting growth of nasopharyngeal carcinoma in vitro and in vivo by To, Yuk Fai, Sun, Raymond Wai‐Yin, Chen, Yongxiong, Chan, Vera Sau‐Fong, Yu, Wing‐Yiu, Tam, Paul Kwong‐Hang, Che, Chi‐Ming, Lin, Chen‐Lung Steve

“…Nasopharyngeal carcinoma (NPC) is a common neoplasm in Southeastern Asia, and cisplatin‐containing regimens for combinational chemotherapy are widely used for…”
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