Search Results - "Chan, Sau Hing"

Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines by Kok, Stanton Hon Lung, Gambari, Roberto, Chui, Chung Hin, Yuen, Marcus Chun Wah, Lin, Eva, Wong, Raymond Siu Ming, Lau, Fung Yi, Cheng, Gregory Yin Ming, Lam, Wing Sze, Chan, Sau Hing, Lam, Kim Hung, Cheng, Chor Hing, Lai, Paul Bo Shan, Yu, Michael Wing Yiu, Cheung, Filly, Tang, Johnny Cheuk On, Chan, Albert Sun Chi

“…Phthalic anhydride is a highly toxic substance, facing, however, the problem of hydrolysis. In fact, it is rapidly hydrolyzed in aqueous medium, generating…”
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Organocatalytic Asymmetric Aldol Reaction of Ketones with β,γ-Unsaturated α-Keto Esters: An Efficient Access to Chiral Tertiary Alcohol Skeletons by Li, Pengfei, Chan, Sau Hing, Chan, Albert S. C., Kwong, Fuk Yee

“…This update describes a highly efficient organocatalytic aldol reaction of ketones and β,γ‐unsaturated α‐keto esters for constructing the chiral tertiary…”
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Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma by Chan, Dessy, Tsoi, Miriam Yuen-Tung, Liu, Christina Di, Chan, Sau-Hing, Law, Simon Ying-Kit, Chan, Kwok-Wah, Chan, Yuen-Piu, Gopalan, Vinod, Lam, Alfred King-Yin, Tang, Johnny Cheuk-On

“…To identify the downstream regulated genes of GAEC1 oncogene in esophageal squamous cell carcinoma and their clinicopathological significance. The…”
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Anti-cancer Effects of a Novel Quinoline Derivative 83b1 on Human Esophageal Squamous Cell Carcinoma through Down-Regulation of COX-2 mRNA and PGE2 by Pun, Ivan Ho Yuen, Chan, Dessy, Chan, Sau Hing, Chung, Po Yee, Zhou, Yuan Yuan, Law, Simon, Lam, Alfred King Yin, Chui, Chung Hin, Chan, Albert Sun Chi, Lam, Kim Hung, Tang, Johnny Cheuk On

“…PURPOSE83b1 is a novel quinoline derivative that has been shown to inhibit cancer growth in human esophageal squamous cell carcinoma (ESCC). This study was…”
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The preparation and in vitro antiproliferative activity of phthalimide based ketones on MDAMB-231 and SKHep-1 human carcinoma cell lines by Chan, Sau Hing, Lam, Kim Hung, Chui, Chung Hin, Gambari, Roberto, Yuen, Marcus Chun Wah, Wong, Raymond Siu Ming, Cheng, Gregory Yin Ming, Lau, Fung Yi, Au, Yiu Kwok, Cheng, Chor Hing, Lai, Paul Bo Shan, Kan, Chi Wai, Kok, Stanton Hon Lung, Tang, Johnny Cheuk On, Chan, Albert Sun Chi

“…The ‘one pot’ condensation reaction for the synthesis and potent antiproliferative inhibition of α-phthalimide based ketones is reported here…”
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Organocatalytic asymmetric Michael-type reaction between β,γ-unsaturated α-keto ester and α-nitro ketone by Li, Pengfei, Chan, Sau Hing, Chan, Albert S C, Kwong, Fuk Yee

“…A Michael-type reaction of β,γ-unsaturated α-keto ester and α-nitro ketone was established. With a thiourea catalyst derived from cinchona alkaloid, the…”
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Synthesis of 8‑Hydroxyquinoline Derivatives as Novel Antitumor Agents by Chan, Sau Hing, Chui, Chung Hin, Chan, Shun Wan, Kok, Stanton Hon Lun, Chan, Dessy, Tsoi, Miriam Yuen Tung, Leung, Polly Hang Mei, Lam, Alfred King Yin, Chan, Albert Sun Chi, Lam, Kim Hung, Tang, Johnny Cheuk On

“…This letter describes the preparation of quinoline derivatives and their cytotoxic potentials toward human carcinoma cell lines. Among the selected compounds,…”
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Catalyst-free aza-Michael addition of azole to β,γ-unsaturated-α-keto ester: an efficient access to C–N bond formation by Wang, Jun, Li, Peng-Fei, Chan, Sau Hing, Chan, Albert S.C., Kwong, Fuk Yee

“…An efficient aza-Michael addition of azoles to β,γ-unsaturated-α-keto esters under room temperature conditions has been developed. In this conjugate addition,…”
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Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems by Chan, Sau Hing, Lam, Kim Hung, Li, Yue-Ming, Xu, Lijin, Tang, Weijun, Lam, Fuk Loi, Lo, Wai Hung, Yu, Wing Yiu, Fan, Qinghua, Chan, Albert S.C.

“…The iridium complex-catalyzed asymmetric hydrogenation of quinolines in a DMPEG/hexane biphasic system was studied. Catalysts with C 2-symmetric ligands such…”
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Anti-cancer Effects of a Novel Quinoline Derivative 83b1 on Human Esophageal Squamous Cell Carcinoma through Down-Regulation of COX-2 mRNA and PGE 2 by Pun, Ivan Ho Yuen, Chan, Dessy, Chan, Sau Hing, Chung, Po Yee, Zhou, Yuan Yuan, Law, Simon, Lam, Alfred King Yin, Chui, Chung Hin, Chan, Albert Sun Chi, Lam, Kim Hung, Tang, Johnny Cheuk On

“…83b1 is a novel quinoline derivative that has been shown to inhibit cancer growth in human esophageal squamous cell carcinoma (ESCC). This study was conducted…”
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In vitro cytotoxicity of (-)-EGCG octaacetate on MDAMB-231 and SKHep-1 human carcinoma cells: A pharmacological consideration on prodrug design by Kok, Stanton, Wong, Raymond, Gambari, Roberto, Cheung, Filly, Lam, Wing, Lau, Fung, Cheng, Gregory, Cheng, Chor, Lam, Kim, Chan, Sau, Tang, Johnny, Chui, Chung, Ho, Kwok

“…Esterification of acetate with generic pharmaceutical compound has been commonly employed to produce ester prodrug for improving its potency when compared with…”
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