Search Results - "Chan, O.K."

Formation of TiN Grid on NiTi by Laser Gas Nitriding for Improving Wear Resistance in Hanks＇ Solution by Ng, C.H., Chan, O.K., Man, H.C.

“…Laser gas nitriding （LGN） is a common surface modification method to enhance the wear resistance of titanium （Ti） alloys, which are known to have poor…”
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Corticosterone Methyl Oxidase Deficiency Type 1 with Normokalemia in an Infant by Üstyol, Ala, Atabek, Mehmet Emre, Taylor, Norman, Yeung, Matthew Chun-Wing, Chan, Angel O K

“…Isolated aldosterone synthase deficiency may result in life-threatening salt-wasting and failure to thrive. The condition involves hyperkalemia accompanying…”
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Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature by Chan, Angel O. K., Chung, Jacqueline P. W., Law, Tracy S. M., Kwan, Angel H. W., Wong, W. S., Chan, Angela Z., Wong, Felix C. K., Kwok, Jeffrey S. S.

“…We describe a case of a 24-year-old overweight woman who presented with hirsutism, secondary amenorrhea, clitoromegaly, and symptoms of diabetes mellitus (DM)…”
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Perioperative Prophylactic Internal Iliac Artery Balloon Occlusion in the Prevention of Postpartum Hemorrhage in Placenta Previa: A Randomized Controlled Trial by Yu, S.C.H., Cheng, Y.K.Y., Tse, W.T., Sahota, D.S., Chung, M.Y., Wong, S.S.M., Chan, O.K., Leung, T.Y.

“…(Am J Obstet Gynecol. 2020;223:117.e1–13) Placenta previa is a major cause of postpartum hemorrhage (PPH) and maternal death worldwide. As cesarean delivery…”
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Knowledge on hepatitis B infection among pregnant women in a high endemicity area by Chan, Oi Ka, Lao, Terence T, Suen, Stephen S.H, Lau, Tze Kin, Leung, Tak Yeung

“…Abstract Objective To assess the knowledge on hepatitis B virus (HBV) infection and associated factors among expectant mothers in an endemic region. Methods A…”
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A rare cause of hyperandrogenism and elevated 17-OHP in a young woman by Wong, Felix C.K., Chan, Angela Z., Wong, W.S., Kwan, Angel H.W., Law, Tracy S.M., Chung, Jacqueline P.W., Kwok, Jeffrey S.S., Chan, Angel O.K.

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Performance of in silico analysis in predicting the effect of non-synonymous variants in inherited steroid metabolic diseases by Chan, Angel O.K.

“…•SIFT and PolyPhen-2 had high concordance in testing genes of steroidogenic diseases.•PON-P behaved differently from the other two programs.•The performance of…”
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Urinary steroid profiling in the diagnosis of congenital adrenal hyperplasia and disorders of sex development: Experience of a urinary steroid referral centre in Hong Kong by Chan, Angel O.K., Shek, C.C.

“…Deficiency in any one of the steroidogenic enzymes may result in congenital adrenal hyperplasia (CAH) and disorders of sex development (DSD). Urinary steroid…”
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New strategies for detecting steroid metabolic disorders--paneling vs profiling by Taylor, Norman F, Chan, Angel O K

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Delayed diagnosis of adrenal insufficiency in a patient with severe penoscrotal hypospadias due to two novel P450 side-change cleavage enzyme (CYP11A1) mutations (p.R360W; p.R405X) by Parajes, Silvia, Chan, Angel OK, But, W M, Rose, Ian T, Taylor, Angela E, Dhir, Vivek, Arlt, Wiebke, Krone, Nils

“…ContextCytochrome P450 side-chain cleavage enzyme (CYP11A1) catalyses the first and rate-limiting step of steroidogenesis, the conversion of cholesterol to…”
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Congenital adrenal hyperplasia presenting as a large adrenal incidentaloma in an elderly man by Hui, Elaine, Lee, Alan C. H., Lang, Brian H. H., Chan, Angel O. K., Lam, Karen S. L., Tan, Kathryn C. B.

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The reference interval of thyroid-stimulating hormone in Hong Kong Chinese by Chan, Angel O K, Iu, Y P, Shek, C C

“…The upper reference limit of thyroid-stimulating hormone (TSH) is critical for defining patients with subclinical hypothyroidism, a condition which carries a…”
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The first case series of Chinese patients in Hong Kong with familial Alzheimer's disease compared with those with biomarker-confirmed sporadic late-onset Alzheimer's disease by Shea, Y F, Chu, L W, Lee, S C, Chan, A Ok

“…Patients with familial Alzheimer's disease are being increasingly reported in Hong Kong. The objectives of this study were to report the clinical features of…”
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Aetiological bases of 46,XY disorders of sex development in the Hong Kong Chinese population by Chan, Angel O K, But, W M, Lee, C Y, Lam, Y Y, Ng, K L, Loung, P Y, Lam, Aimen, Cheng, C W, Shek, C C, Wong, W S, Wong, K F, Wong, M Y, Tse, W Y

“…Disorders of sex development are due to congenital defects in chromosomal, gonadal, or anatomical sex development. The objective of this study was to determine…”
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A common PRRT2 mutation in familial paroxysmal kinesigenic dyskinesia in Hong Kong: a case series of 16 patients by Law, C Y, Yeung, W L, Cheung, Y F, Chan, H F, Fung, E, Hui, J, Yung, I Ok, Yuen, Y P, Chan, A Ok, Lam, C W

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The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene by Hui, Elaine, Yeung, Matthew Cw, Cheung, Pik To, Kwan, Elaine, Low, Louis, Tan, Kathryn Cb, Lam, Karen Sl, Chan, Angel Ok

“…Aldosterone synthase (CYP11B2) deficiency is a rare autosomal recessive disorder, usually presenting with severe salt-wasting in infancy or stress-induced…”
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Hypertriglyceridaemia-induced pancreatitis: a contributory role of capecitabine? by Chan, H Y, Ng, C M, Tiu, S C, Chan, Angel O K, Shek, C C

“…Capecitabine is an orally administered pro-drug of 5-fluorouracil that confers superior disease-free survival and presumably has a more favourable side-effect…”
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Molecular analysis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency in Hong Kong Chinese patients by Chan, Angel O.K., But, W.M., Ng, K.L., Wong, L.M., Lam, Y.Y., Tiu, S.C., Lee, K.F., Lee, C.Y., Loung, P.Y., Berry, Ian R., Brown, Rebecca, Charlton, Ruth, Cheng, C.W., Ho, Y.C., Tse, W.Y., Shek, C.C.

“…► The frequency of CYP21A2 mutations in Hong Kong Chinese differs from other Asian populations. ► Testing for gross deletion is mandatory to avoid…”
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Reference intervals of common serum analytes of Hong Kong Chinese by Chan, A O K, Lee, K C, Leung, J N S, Shek, C C

“…Setting up reference intervals from the local service populations is one of the major responsibilities of clinical laboratories. Yet, this task is difficult to…”
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Long-term outcome of kidney transplantation in a patient with coexisting lipoprotein glomerulopathy and fibrillary glomerulonephritis by Cheung, Chi Yuen, Chan, Angel O.K., Chan, Gordon P.T., Iu, Heidi Y.P., Shek, Chi Chung, Chau, Ka Foon

“…Both lipoprotein glomerulopathy (LPG) and fibrillary glomerulonephritis (FGN) are rare causes of end-stage renal disease (ESRD), and the literature concerning…”
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