Search Results - "Chan, Noel"

Peripheral Oxygen Saturation in Older Persons Wearing Nonmedical Face Masks in Community Settings by Chan, Noel C, Li, Karen, Hirsh, Jack

“…This study describes changes in portable oximeter–measured peripheral oxygen saturation (Spo2 or O2sat) in older adults before, during, and after wearing a…”
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COVID-19 coagulopathy, thrombosis, and bleeding by Chan, Noel C., Weitz, Jeffrey I.

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Direct oral anticoagulants: evidence and unresolved issues by Chan, Noel, Sobieraj-Teague, Magdalena, Eikelboom, John W

“…Currently licenced direct oral anticoagulants selectively target thrombin (eg, dabigatran) or coagulation factor Xa (eg, apixaban, betrixaban, edoxaban, and…”
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Recurrent Thrombosis and Bleeding in Patients with Cancer-Associated Venous Thromboembolism Receiving Anticoagulation: Are These Modifiable Risk Factors for Mortality? by Xu, Ke, Chan, Noel C

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Antithrombotic Agents: New Directions in Antithrombotic Therapy by Chan, Noel C, Weitz, Jeffrey I

“…Recent advances in our understanding of the contribution of thrombin generation to arterial thrombosis and the role of platelets in venous thrombosis have…”
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Thromboprophylaxis After Hip or Knee Arthroplasty by Chan, Noel C., Bhandari, Mohit

“…In the 1960s, the modern era of joint arthroplasty was launched following the first successful implantation of a long-lasting hip endoprosthesis. More than…”
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Novel antithrombotic strategies for treatment of venous thromboembolism by Weitz, Jeffrey I., Chan, Noel C.

“…Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common cause of vascular death after…”
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Advances in Antithrombotic Therapy by Weitz, Jeffrey I, Chan, Noel C

“…Thrombosis remains a major cause of morbidity and mortality. Consequently, advances in antithrombotic therapy are needed to reduce the disease burden. This…”
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Glaucoma as Neurodegeneration in the Brain by Chan, Jane W, Chan, Noel C Y, Sadun, Alfredo A

“…Glaucoma, a group of diseases characterized by progressive optic nerve degeneration that results in irreversible blindness, can be considered a…”
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Prevention of Venous Thromboembolism in 2020 and Beyond by Nicholson, Matthew, Chan, Noel, Bhagirath, Vinai, Ginsberg, Jeffrey

“…Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism…”
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New Therapeutic Targets for the Prevention and Treatment of Venous Thromboembolism With a Focus on Factor XI Inhibitors by Chan, Noel C., Weitz, Jeffrey I.

“…FXI (factor XI) and FXII (factor XII) have emerged as targets for new anticoagulants that have the potential to be both more efficacious and safer than the…”
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Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials by Weitz, Jeffrey I, Chan, Noel C

“…Many patients with venous thromboembolism (VTE) are at risk of recurrence if anticoagulant therapy is stopped. Whereas 3 months of anticoagulation treatment is…”
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Human papilloma virus and atherosclerotic cardiovascular disease by Chan, Noel C, Lawson, James S, Hirsh, Jack

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Laboratory measurement of the direct oral anticoagulants by Dale, Brian J., Chan, Noel C., Eikelboom, John W.

“…Summary Direct oral anticoagulants (DOACs), including the direct thrombin inhibitor, dabigatran, and the direct factor Xa (FXa) inhibitors, rivaroxaban,…”
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Evolving Treatments for Arterial and Venous Thrombosis: Role of the Direct Oral Anticoagulants by Chan, Noel C, Eikelboom, John W, Weitz, Jeffrey I

“…The direct oral anticoagulants (DOACs) represent a major advance in oral anticoagulant therapy and have replaced the vitamin K antagonists as the preferred…”
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Reduction in Mortality following Elective Major Hip and Knee Surgery: A Systematic Review and Meta-Analysis by Xu, Ke, Chan, Noel C, Ibrahim, Quazi, Kruger, Paul, Sinha, Smita, Bhagirath, Vinai, Ginsberg, Jeffrey, Bangdiwala, Shrikant, Guyatt, Gordon, Eikelboom, John, Hirsh, Jack

“…Systematic reviews reporting time trends in mortality following major orthopaedic surgery are few and have limitations. They reported on only a fraction (<…”
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Ciraparantag as a potential universal anticoagulant reversal agent by Chan, Noel C, Weitz, Jeffrey I

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The use of optical coherence tomography in neuro-ophthalmology by Chan, Noel C.Y, Chan, Carmen K.M

“…PURPOSE OF REVIEWIn the last decade, with the advances of optical coherence tomography (OCT) technology, different imaging protocols and analysis algorithms…”
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Clinical Studies with Anticoagulants that Have Changed Clinical Practice by Hirsh, Jack, de Vries, Tim A C, Eikelboom, John W, Bhagirath, Vinai, Chan, Noel C

“…Anticoagulant therapy is the cornerstone of treatment and prevention of arterial and venous thromboembolism. Taking a historical perspective, starting in the…”
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In pregnant women with suspected VTE and low/intermediate or unlikely pretest probability, D-dimer rules out VTE at 3 mo by Chan, Noel C., Weitz, Jeffrey I.

“…Chan said that compared with nonpregnant women, the daily risk for VTE increases at least 5-fold during pregnancy and 20-fold in the 6 weeks after delivery…”
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