Search Results - "Chan, Miu Shan"

Two-photon fluorescence probes for imaging of mitochondria and lysosomes by Yang, Wanggui, Chan, Pui Shan, Chan, Miu Shan, Li, King Fai, Lo, Pik Kwan, Mak, Nai Ki, Cheah, Kok Wai, Wong, Man Shing

“…Novel biocompatible cyanines show not only a very large two-photon cross-section of up to 5130 GM at 910 nm in aqueous medium for high-contrast and -brightness…”
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Cancer-Cell-Specific Mitochondria-Targeted Drug Delivery by Dual-Ligand-Functionalized Nanodiamonds Circumvent Drug Resistance by Chan, Miu Shan, Liu, Ling Sum, Leung, Hoi Man, Lo, Pik Kwan

“…We demonstrate a nanotechnology approach for the development of cancer-cell-specific subcellular organelle-targeted drug nanocarriers based on photostable…”
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Stepwise Ligand-induced Self-assembly for Facile Fabrication of Nanodiamond–Gold Nanoparticle Dimers via Noncovalent Biotin–Streptavidin Interactions by Chan, Miu Shan, Landig, Renate, Choi, Joonhee, Zhou, Hengyun, Liao, Xing, Lukin, Mikhail D, Park, Hongkun, Lo, Pik Kwan

“…Nanodiamond–gold nanoparticle (ND-AuNP) dimers constitute a potent tool for controlled thermal heating of biological systems on the nanoscale, by combining a…”
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Indole-based Cyanine as a Nuclear RNA-Selective Two-Photon Fluorescent Probe for Live Cell Imaging by Guo, Lei, Chan, Miu Shan, Xu, Di, Tam, Dick Yan, Bolze, Frédéric, Lo, Pik Kwan, Wong, Man Shing

“…We have demonstrated that the subcellular targeting properties of the indole-based cyanines can be tuned by the functional substituent attached onto the indole…”
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A Reversible DNA Logic Gate Platform Operated by One- and Two-Photon Excitations by Tam, Dick Yan, Dai, Ziwen, Chan, Miu Shan, Liu, Ling Sum, Cheung, Man Ching, Bolze, Frederic, Tin, Chung, Lo, Pik Kwan

“…We demonstrate the use of two different wavelength ranges of excitation light as inputs to remotely trigger the responses of the self‐assembled DNA devices…”
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Mitochondrial Delivery of Therapeutic Agents by Amphiphilic DNA Nanocarriers by Chan, Miu Shan, Tam, Dick Yan, Dai, Ziwen, Liu, Ling Sum, Ho, Jonathan Weng-Thim, Chan, Man Lee, Xu, Di, Wong, Man Shing, Tin, Chung, Lo, Pik Kwan

“…The first example of mitochondrial delivery of the anticancer drug doxorubicin (Dox) is presented by lipid‐functionalized DNA nanocages (LNCs). Dox localized…”
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Nanoneedle-Assisted Delivery of Site-Selective Peptide-Functionalized DNA Nanocages for Targeting Mitochondria and Nuclei by Chan, Miu Shan, Lo, Pik Kwan

“…Peptide‐functionalized DNA nano‐objects selectively target mitochondria and the nucleus by means of nanoneedle‐assisted delivery. This technology preserves the…”
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Penetrating the Blood–Brain Barrier by Self-Assembled 3D DNA Nanocages as Drug Delivery Vehicles for Brain Cancer Therapy by Tam, Dick Yan, Ho, Jonathan Weng-Thim, Chan, Miu Shan, Lau, Cia Hin, Chang, Tristan Juin Han, Leung, Hoi Man, Liu, Ling Sum, Wang, Fei, Chan, Leanne Lai Hang, Tin, Chung, Lo, Pik Kwan

“…The development of biocompatible drug delivery vehicles for cancer therapy in the brain remains a big challenge. In this study, we designed self-assembled DNA…”
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Dual-Function, Cationic, Peptide-Coated Nanodiamond Systems: Facilitating Nuclear-Targeting Delivery for Enhanced Gene Therapy Applications by Leung, Hoi Man, Chan, Miu Shan, Liu, Ling Sum, Wong, Sze Wing, Lo, Tsz Wan, Lau, Cia-Hin, Tin, Chung, Lo, Pik Kwan

“…Nuclear-targeting therapy is considered to be a promising strategy of disease treatment. So far, developing biocompatible and nucleus-permeable delivery…”
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Targeted brain tumor imaging by using discrete biopolymer-coated nanodiamonds across the blood-brain barrier by Leung, Hoi Man, Lau, Cia Hin, Ho, Jonathan Weng-Thim, Chan, Miu Shan, Chang, Tristan Juin Han, Law, Lok Hin, Wang, Fei, Tam, Dick Yan, Liu, Ling Sum, Chan, Kannie Wai Yan, Tin, Chung, Lo, Pik Kwan

“…Short circulation lifetime, poor blood-brain barrier (BBB) permeability and low targeting specificity limit nanovehicles from crossing the vascular barrier and…”
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Conformational Change of Self-Assembled DNA Nanotubes Induced by Two-Photon Excitation by Dai, Ziwen, Tam, Dick Yan, Xu, Hailiang, Chan, Miu Shan, Liu, Ling Sum, Bolze, Frédéric, Sun, Xiao Hua, Lo, Pik Kwan

“…Two‐photon‐regulated, shape‐changing DNA nanostructures are demonstrated by integrating a DNA nanotube with a two‐photon photocleavable module that enables the…”
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Correction to Penetrating the Blood–Brain Barrier by Self-Assembled 3D DNA Nanocages as Drug Delivery Vehicles for Brain Cancer Therapy by Tam, Dick Yan, Weng-Thim Ho, Jonathan, Chan, Miu Shan, Lau, Cia Hin, Han Chang, Tristan Juin, Leung, Hoi Man, Liu, Ling Sum, Wang, Fei, Hang Chan, Leanne Lai, Tin, Chung, Lo, Pik Kwan

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Enzyme-Free Amplification by Nano Sticky Balls for Visual Detection of ssDNA/RNA Oligonucleotides by Chen, Shan, Chu, Lok Ting, Yeung, Pak Piu, Zhao, Zichen, Bao, Yuanye, Chan, Miu Shan, Lo, Pik Kwan, Chen, Ting-Hsuan

“…Visual detection of nucleic acids provides simple and rapid screening for infectious diseases or environmental pathogens. However, sensitivity is the current…”
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G‐Quadruplex‐Mediated Molecular Switching of Self‐Assembled 3D DNA Nanocages by Tam, Dick Yan, Leung, Hoi Man, Chan, Miu Shan, Lo, Pik Kwan

“…We demonstrated a strategy to reversibly extend and contract 3D DNA nanocages based on G‐rich DNA strands as scaffolds in the presence of K+ or chelating…”
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Aggregation-free DNA nanocage/Quantum Dot complexes based on electrostatic adsorption by Wang, Zhenguang, Yan, Tam Dick, Susha, Andrei S., Chan, Miu Shan, Kershaw, Stephen V., Lo, Pik Kwan, Rogach, Andrey L.

“…[Display omitted] •DNA nanocage/Quantum Dot complexes are constructed using electrostatic adsorption.•The complexes are in an aggregation-free state.•The…”
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A Reversible DNA Logic Gate Platform Operated by One- and Two-Photon Excitations by Tam, Dick Yan, Dai, Ziwen, Chan, Miu Shan, Liu, Ling Sum, Cheung, Man Ching, Bolze, Frederic, Tin, Chung, Lo, Pik Kwan

“…We demonstrate the use of two different wavelength ranges of excitation light as inputs to remotely trigger the responses of the self‐assembled DNA devices…”
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