Search Results - "Chan, Mark Yan Yee"

Hepatic steatosis and advanced hepatic fibrosis are independent predictors of long‐term mortality in acute myocardial infarction by Chin, YipHan, Lim, Jieyu, Kong, Gwyneth, Ng, Cheng Han, Goh, Rachel, Muthiah, Mark, Mehta, Anurag, Chong, Bryan, Lin, Chaoxing, Chan, Kai En, Kong, William, Poh, Kian Keong, Foo, Roger, Chai, Ping, Yeo, Tiong‐Cheng, Low, Adrian F., Lee, Chi Hang, Tan, Huay Cheem, Chan, Mark Yan‐Yee, Richards, A Mark, Loh, Poay‐Huan, Chew, Nicholas W. S.

“…Aim To examine the prevalence and prognosis of hepatic steatosis and fibrosis in post‐acute myocardial infarction (AMI) patients. Methods Patients presenting…”
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The prognostic value of metabolic dysfunction‐associated steatotic liver disease in acute myocardial infarction: A propensity score‐matched analysis by Kong, Gwyneth, Cao, Grace, Koh, Jaycie, Chan, Siew Pang, Zhang, Audrey, Wong, Esther, Chong, Bryan, Jauhari, Silingga Metta, Wang, Jiong‐Wei, Mehta, Anurag, Figtree, Gemma A., Mamas, Mamas A., Ng, Gavin, Chan, Koo Hui, Chai, Ping, Low, Adrian F., Lee, Chi Hang, Yeo, Tiong Cheng, Yip, James, Foo, Roger, Tan, Huay Cheem, Huang, Daniel Q., Muthiah, Mark, Chan, Mark Yan‐Yee, Loh, Poay‐Huan, Chew, Nicholas W. S.

“…Aim Patients with metabolic dysfunction‐associated steatotic liver disease (MASLD) are at increased risk of incident cardiovascular disease. However, the…”
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Association between smoking status and outcomes in myocardial infarction patients undergoing percutaneous coronary intervention by Sia, Ching-Hui, Ko, Junsuk, Zheng, Huili, Ho, Andrew Fu-Wah, Foo, David, Foo, Ling-Li, Lim, Patrick Zhan-Yun, Liew, Boon Wah, Chai, Ping, Yeo, Tiong-Cheng, Tan, Huay-Cheem, Chua, Terrance, Chan, Mark Yan-Yee, Tan, Jack Wei Chieh, Bulluck, Heerajnarain, Hausenloy, Derek J.

“…Smoking is one of the leading risk factors for cardiovascular diseases, including ischemic heart disease and hypertension. However, in acute myocardial…”
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Anticoagulation for the treatment of left ventricular thrombus in patients with acute myocardial infarction and renal impairment by Sia, Ching-Hui, Leow, Aloysius Sheng-Ting, Tan, Benjamin Yong-Qiang, Yeo, Leonard Leong-Litt, Chan, Mark Yan-Yee, Loh, Joshua Ping-Yun

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Surprisingly low incidence of left ventricular thrombosis in anterior ST‐segment elevation myocardial infarction by Leow, Aloysius Sheng‐Ting, Sia, Ching‐Hui, Tan, Benjamin Yong‐Qiang, Chan, Mark Yan‐Yee, Loh, Joshua Ping‐Yun

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Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population by Chang, Xuling, Dorajoo, Rajkumar, Han, Yi, Wang, Ling, Liu, Jianjun, Khor, Chiea‐Chuen, Low, Adrian F., Chan, Mark Yan‐Yee, Yuan, Jian‐Min, Koh, Woon‐Puay, Friedlander, Yechiel, Heng, Chew‐Kiat

“…Background Haptoglobin (Hp) is a plasma protein with strong anti‐inflammation and antioxidant activities. Its plasma level is known to be inversely associated…”
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Detection of ADTRP in circulation and its role as a novel biomarker for coronary artery disease by Ooi, Delicia Shu Qin, Ong, Sze Min, Eng, Ming Hui, Chan, Yiong Huak, Lee, Yung Seng, Low, Adrian Fatt Hoe, Chan, Mark Yan-Yee, Heng, Chew-Kiat

“…Androgen dependent tissue factor pathway inhibitor regulating protein (ADTRP) is a novel protein associated with coronary artery disease (CAD) susceptibility,…”
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Optimal glucose, HbA1c, glucose-HbA1c ratio and stress-hyperglycaemia ratio cut-off values for predicting 1-year mortality in diabetic and non-diabetic acute myocardial infarction patients by Sia, Ching-Hui, Chan, Mervyn Huan-Hao, Zheng, Huili, Ko, Junsuk, Ho, Andrew Fu-Wah, Chong, Jun, Foo, David, Foo, Ling-Li, Lim, Patrick Zhan-Yun, Liew, Boon Wah, Chai, Ping, Yeo, Tiong-Cheng, Tan, Huay-Cheem, Chua, Terrance, Chan, Mark Yan-Yee, Tan, Jack Wei Chieh, Bulluck, Heerajnarain, Hausenloy, Derek J

“…Stress-induced hyperglycaemia at time of hospital admission has been linked to worse prognosis following acute myocardial infarction (AMI). In addition to…”
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Deletion of Mfsd2b impairs thrombotic functions of platelets by Chandrakanthan, Madhuvanthi, Nguyen, Toan Quoc, Hasan, Zafrul, Muralidharan, Sneha, Vu, Thiet Minh, Li, Aaron Wei Liang, Le, Uyen Thanh Nha, Thi Thuy Ha, Hoa, Baik, Sang-Ha, Tan, Sock Hwee, Foo, Juat Chin, Wenk, Markus R., Cazenave-Gassiot, Amaury, Torta, Federico, Ong, Wei Yi, Chan, Mark Yan Yee, Nguyen, Long N.

“…We recently discovered that Mfsd2b, which is the S1P exporter found in blood cells. Here, we report that Mfsd2b is critical for the release of all S1P species…”
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The Lipid Paradox is present in ST-elevation but not in non-ST-elevation myocardial infarction patients: Insights from the Singapore Myocardial Infarction Registry by Sia, Ching-Hui, Zheng, Huili, Ho, Andrew Fu-Wah, Bulluck, Heerajnarain, Chong, Jun, Foo, David, Foo, Ling-Li, Lim, Patrick Zhan Yun, Liew, Boon Wah, Tan, Huay-Cheem, Yeo, Tiong-Cheng, Chua, Terrance Siang Jin, Chan, Mark Yan-Yee, Hausenloy, Derek J.

“…Lowering low-density lipoprotein (LDL-C) and triglyceride (TG) levels form the cornerstone approach of cardiovascular risk reduction, and a higher high-density…”
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Characterisation of acute ischemic stroke in patients with left ventricular thrombi after myocardial infarction by Leow, Aloysius Sheng-Ting, Sia, Ching-Hui, Tan, Benjamin Yong-Qiang, Kaur, Rajinderdeep, Yeo, Tiong-Cheng, Chan, Mark Yan-Yee, Tay, Edgar Lik-Wui, Seet, Raymond Chee-Seong, Loh, Joshua Ping-Yun, Yeo, Leonard Leong-Litt

“…Acute ischemic stroke (AIS) is a feared complication in post-acute myocardial infarction (AMI) patients who develop left ventricular (LV) thrombus. There is…”
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Comparison of the modified Singapore myocardial infarction registry risk score with GRACE 2.0 in predicting 1-year acute myocardial infarction outcomes by Sia, Ching-Hui, Zheng, Huili, Ko, Junsuk, Ho, Andrew Fu-Wah, Foo, David, Foo, Ling-Li, Lim, Patrick Zhan-Yun, Liew, Boon Wah, Chai, Ping, Yeo, Tiong-Cheng, Tan, Huay-Cheem, Chua, Terrance, Chan, Mark Yan-Yee, Tan, Jack Wei Chieh, Fox, Keith A. A., Bulluck, Heerajnarain, Hausenloy, Derek J.

“…Risk stratification plays a key role in identifying acute myocardial infarction (AMI) patients at higher risk of mortality. However, current AMI risk scores…”
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Underlying Differences in the Treatment of Left Ventricular Thrombus With Non-Vitamin K Antagonist Oral Anticoagulants by Leow, Aloysius Sheng-Ting, Sia, Ching-Hui, Tan, Benjamin Yong-Qiang, Chan, Mark Yan-Yee, Loh, Joshua Ping-Yun

“…[...]whereas initial reports of NOAC use in the treatment of LV thrombus are encouraging, the rate of bleeding complication should be interpreted while taking…”
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Prognostication of Valvular Aortic Stenosis Using Tissue Doppler Echocardiography: Underappreciated Importance of Late Diastolic Mitral Annular Velocity by Poh, Kian-Keong, MBBChir, MRCP, FASE, Chan, Mark Yan-Yee, MBBS, MRCP, Yang, Hong, MD, RDCS, Yong, Quek-Wei, MBBS, MRCP, Chan, Yiong-Huak, PhD, Ling, Lieng H., MBBS, MD, FRCP

“…Background Intact left atrial booster pump function helps maintain cardiac compensation in patients with aortic valve stenosis (AS). Because late diastolic…”
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Prognostic Outcomes in Acute Myocardial Infarction Patients Without Standard Modifiable Risk Factors: A Multiethnic Study of 8,680 Asian Patients by Kong, Gwyneth, Chew, Nicholas W S, Ng, Cheng Han, Chin, Yip Han, Lim, Oliver Z H, Ambhore, Anand, Ng, Gavin, Kong, William, Poh, Kian-Keong, Foo, Roger, Yip, James, Yeo, Tiong-Cheng, Low, Adrian Fatt-Hoe, Lee, Chi-Hang, Chan, Mark Yan-Yee, Tan, Huay-Cheem, Loh, Poay-Huan

“…An increasing proportion of patients with acute myocardial infarction (AMI) are presenting without standard modifiable risk factors (SMuRFs) of hypertension,…”
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Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia by Han, Yi, Dorajoo, Rajkumar, Chang, Xuling, Wang, Ling, Khor, Chiea-Chuen, Sim, Xueling, Cheng, Ching-Yu, Shi, Yuan, Tham, Yih Chung, Zhao, Wanting, Chee, Miao Ling, Sabanayagam, Charumathi, Chee, Miao Li, Tan, Nicholas, Wong, Tien Yin, Tai, E-Shyong, Liu, Jianjun, Goh, Daniel Y. T., Yuan, Jian-Min, Koh, Woon-Puay, van Dam, Rob M., Low, Adrian F., Chan, Mark Yan-Yee, Friedlander, Yechiel, Heng, Chew-Kiat

“…Recent genome-wide association studies (GWAS) have identified multiple loci associated with coronary artery disease (CAD) among predominantly Europeans…”
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Comparison of Mortality Outcomes in Acute Myocardial Infarction Patients With or Without Standard Modifiable Cardiovascular Risk Factors by Sia, Ching-Hui, Ko, Junsuk, Zheng, Huili, Ho, Andrew Fu-Wah, Foo, David, Foo, Ling-Li, Lim, Patrick Zhan-Yun, Liew, Boon Wah, Chai, Ping, Yeo, Tiong-Cheng, Yip, James W L, Chua, Terrance, Chan, Mark Yan-Yee, Tan, Jack Wei Chieh, Figtree, Gemma, Bulluck, Heerajnarain, Hausenloy, Derek J

“…Acute myocardial infarction (AMI) cases have decreased in part due to the advent of targeted therapies for standard modifiable cardiovascular disease risk…”
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Prevalence and outcomes of concomitant cardiac amyloidosis and aortic stenosis: A systematic review and meta-analysis by Ho, Jamie Sin-Ying, Kor, Qianyi, Kong, William KF, Lim, Yoke Ching, Chan, Mark Yan-Yee, Syn, Nicholas LX, Ngiam, Jinghao Nicholas, Chew, Nicholas WS, Yeo, Tiong-Cheng, Chai, Ping, Poh, Kian-Keong, Wong, Raymond CC, Lin, Weiqin, Sia, Ching-Hui

“…Cardiac amyloidosis (CA) is an increasingly recognised condition in patients with aortic stenosis (AS). However, there is a large variation in the reported…”
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A Factor XIa Inhibitor Engineered from Banded Krait Venom Toxin: Efficacy and Safety in Rodent Models of Arterial and Venous Thrombosis by Chng, Wei Seng, Li, Aaron Wei Liang, Lim, Jasmine Jia Min, Leong, Esther Jia En, Amran, Fathiah S, Kini, R Manjunatha, Chan, Mark Yan Yee, Koh, Cho Yeow

“…Activated factor XI (FXIa) is an important antithrombotic drug target. Clinical and pre-clinical data have demonstrated that its inhibition attenuates…”
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Prevalence and incidence of stroke, white matter hyperintensities, and silent brain infarcts in patients with chronic heart failure: A systematic review, meta-analysis, and meta-regression by Tan, Sean, Ho, Clare Elisabeth Si Min, Teo, Yao Neng, Teo, Yao Hao, Chan, Mark Yan-Yee, Lee, Chi-Hang, Evangelista, Lauren Kay Mance, Lin, Weiqin, Chong, Yao-Feng, Yeo, Tiong-Cheng, Sharma, Vijay Kumar, Wong, Raymond C. C., Tan, Benjamin Y. Q., Yeo, Leonard L. L., Chai, Ping, Sia, Ching-Hui

“…Introduction Heart failure (HF) is associated with ischemic stroke (IS). However, there are limited studies on the prevalence of IS, white matter…”
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