Search Results - "Chan, M.W.Y."

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    Advances in organ-on-a-chip systems for modelling joint tissue and osteoarthritic diseases by Banh, L., Cheung, K.K., Chan, M.W.Y., Young, E.W.K., Viswanathan, S.

    Published in Osteoarthritis and cartilage (01-08-2022)
    “…Joint-on-a-chip (JOC) models are powerful tools that aid in osteoarthritis (OA) research. These microfluidic devices apply emerging organ-on-a-chip technology…”
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    Journal Article
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    A tool for evaluating novel osteoarthritis therapies using multivariate analyses of human cartilage-synovium explant co-culture by Chan, M.W.Y., Gomez-Aristizábal, A., Mahomed, N., Gandhi, R., Viswanathan, S.

    Published in Osteoarthritis and cartilage (01-01-2022)
    “…There is a need to incorporate multiple tissues into in vitro OA models to evaluate novel therapeutics. This approach is limited by inherent donor variability…”
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    Journal Article
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    Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer by Su, P-H, Lin, Y-W, Huang, R-L, Liao, Y-P, Lee, H-Y, Wang, H-C, Chao, T-K, Chen, C-K, Chan, M W Y, Chu, T-Y, Yu, M-H, Lai, H-C

    Published in Oncogene (03-01-2013)
    “…Epigenetic modifications are a driving force in carcinogenesis. However, their role in cancer metastasis remains poorly understood. The present study…”
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    Journal Article
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    Epigenetic silencing of GDF1 disrupts SMAD signaling to reinforce gastric cancer development by Yang, W, Mok, M T S, Li, M S M, Kang, W, Wang, H, Chan, A W, Chou, J-L, Chen, J, Ng, E K W, To, K-F, Yu, J, Chan, M W Y, Chan, F K L, Sung, J J Y, Cheng, A S L

    Published in Oncogene (21-04-2016)
    “…Accumulating evidence reveals the effectiveness of epigenetic therapy in gastric cancer. However, the molecular mechanisms and targets underlying such…”
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    Journal Article
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    Effect of peroxisome proliferator activated receptor γ ligands on growth and gene expression profiles of gastric cancer cells by Leung, W K, Bai, A H C, Chan, V Y W, Yu, J, Chan, M W Y, To, K-F, Wu, J-R, Chan, K-K, Fu, Y-G, Chan, F K L, Sung, J J Y

    Published in Gut (01-03-2004)
    “…Background and aims: Although peroxisome proliferator activated receptor γ (PPARγ) agonists have been implicated in differentiation and growth inhibition of…”
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    Journal Article
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