Search Results - "Chan, M.H."
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1
Basophil activation test discriminates between allergy and tolerance in peanut-sensitized children
Published in Journal of allergy and clinical immunology (01-09-2014)“…Background Most of the peanut-sensitized children do not have clinical peanut allergy. In equivocal cases, oral food challenges (OFCs) are required. However,…”
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2
Topography of claustrum and insula projections to medial prefrontal and anterior cingulate cortices of the common marmoset (Callithrix jacchus)
Published in Journal of comparative neurology (1911) (15-04-2017)“…ABSTRACT The claustrum has been the subject of intense research interest in recent years, driven in large part by its extensive connections with various…”
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3
The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells
Published in Biochimie (01-07-2017)“…Endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR) have been implicated in the pathogenesis of many common human…”
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Contraction-induced Interleukin-6 Gene Transcription in Skeletal Muscle Is Regulated by c-Jun Terminal Kinase/Activator Protein-1
Published in The Journal of biological chemistry (30-03-2012)“…Exercise increases the expression of the prototypical myokine IL-6, but the precise mechanism by which this occurs has yet to be identified. To mimic exercise…”
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Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice
Published in Biochimica et biophysica acta (01-07-2015)“…Hepatic steatosis is often associated with insulin resistance as a hallmark of the metabolic syndrome in the liver. The present study investigated the effects…”
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Activation of PPARα Ameliorates Hepatic Insulin Resistance and Steatosis in High Fructose-Fed Mice Despite Increased Endoplasmic Reticulum Stress
Published in Diabetes (New York, N.Y.) (01-06-2013)“…Endoplasmic reticulum (ER) stress is suggested to cause hepatic insulin resistance by increasing de novo lipogenesis (DNL) and directly interfering with…”
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Exposure to cigarette smoke precipitates simple hepatosteatosis to NASH in high-fat diet fed mice by inducing oxidative stress
Published in Clinical science (1979) (17-09-2021)“…Consumption of diet rich in fat and cigarette smoking (CS) are independent risk factors of non-alcoholic steatohepatitis (NASH), and they often occur together…”
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Cigarette smoking blocks the benefit from reduced weight gain for insulin action by shifting lipids deposition to muscle
Published in Clinical science (1979) (17-07-2020)“…Cigarette smoking (CS) is known to reduce body weight and this often masks its real effect on insulin action. The present study tested the hypothesis that CS…”
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9
Development of metastatic tumor-targeting NIR persistent luminescence nanomaterials to treatment for lung cancer
Published in European journal of cancer (1990) (01-10-2020)Get full text
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10
Screening for the efficacy on lipid accumulation in 3T3-L1 cells is an effective tool for the identification of new anti-diabetic compounds
Published in Biochemical pharmacology (15-09-2012)“…Reducing lipid accumulation in insulin target tissues is critical for the treatment of type 2 diabetes. This study aimed to develop a biochemical assay in…”
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11
PP103. Arterial stiffness in women with previous GDM – A follow up of Chinese HAPO study cohort
Published in Pregnancy hypertension (01-07-2012)“…Introduction It is well known that women with history of gestational diabetes (GDM) are at risk of future DM. Whether they are at a higher risk of hypertension…”
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12
Association Between Obesity and Serum IgE Measurements in a Community Cohort of Chinese Schoolchildren
Published in Journal of allergy and clinical immunology (01-02-2008)“…Elevated serum total IgE concentration was found in less overweight/obese females than those with normal body mass index (odds ratio 0.32, 95% confidence…”
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13
Determinants of China's textile exports: An analysis by gravity model
Published in Journal of the Textile Institute (01-01-2007)“…An abundant supply of raw materials and low-cost labour made China the world's largest producer and exporter of textile products since 2000. The value of…”
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14
Acute and subchronic effects of antipsychotic drugs on cognitive and social deficits after adolescent toluene exposure in mice
Published in Toxicology letters (10-10-2016)Get full text
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15
Extracellular calcium concentration and channel activity involved in aminoglycoside-induced hair cell toxicity in the zebrafish lateral line
Published in Toxicology letters (10-10-2016)Get full text
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16
HSP72 protects against obesity-induced insulin resistance
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2008)“…Patients with type 2 diabetes have reduced gene expression of heat shock protein (HSP) 72, which correlates with reduced insulin sensitivity. Heat therapy,…”
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17
Employment among people with epilepsy in Hong Kong
Published in Epilepsy & behavior (01-11-2021)“…People with epilepsy (PWE) face difficulties in employment. Hong Kong depends heavily on tertiary industry and enjoys a low unemployment rate. However, there…”
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Perceived Social Support and Depression Among Occupational Therapists in Hong Kong During COVID-19 Pandemic
Published in East Asian archives of psychiatry (01-03-2022)“…This study aimed to determine the prevalence of depression and the level of perceived social support among occupational therapists during the pandemic, and to…”
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Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells
Published in Nutrition research (New York, N.Y.) (01-11-2014)“…Abstract Leucine is a key amino acid for initiating translation in muscle cells, but the dose-dependent effects of leucine on intracellular signaling are…”
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Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies
Published in Pharmacology & therapeutics (Oxford) (01-06-2019)“…Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden and is currently the 4th largest cause of death in the world…”
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