Search Results - "Chan, M. T. V"

Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer by Yu, J, Wu, W K K, Liang, Q, Zhang, N, He, J, Li, X, Zhang, X, Xu, L, Chan, M T V, Ng, S S M, Sung, J J Y

“…Whole-genome and transcriptome sequencing were used to discover novel gene fusions in a case of colon cancer. A tumor-specific LACTB2 - NCOA2 fusion…”
Get full text

Risk factors for severe postoperative nausea and vomiting in a randomized trial of nitrous oxide-based vs nitrous oxide-free anaesthesia by Leslie, K., Myles, P.S., Chan, M.T.V., Paech, M.J., Peyton, P., Forbes, A., McKenzie, D.

“…Refractory postoperative nausea and vomiting (PONV) requiring repeated treatment with antiemetic drugs is a miserable experience for the patient that may…”
Get full text

Effect of nitrous oxide on plasma homocysteine and folate in patients undergoing major surgery by Myles, P.S., Chan, M.T.V., Leslie, K., Peyton, P., Paech, M., Forbes, A.

“…Nitrous oxide (N2O) inhibits methionine synthetase resulting in elevated plasma homocysteine (Hcy) concentration after surgery. In epidemiological studies,…”
Get full text

A prospective cohort study comparing early opioid requirement between Chinese from Hong Kong and Caucasian Australians after major abdominal surgery by Konstantatos, A.H., Imberger, G, Angliss, M, Cheng, C.H.K., Meng, A.Z.Y., Chan, M.T.V.

“…The relationship between ethnicity and early opioid consumption is not well understood. Our prospective cohort study tested whether Chinese patients in Hong…”
Get full text

A double‐blind randomised comparison of intravenous patient‐controlled remifentanil with intramuscular pethidine for labour analgesia by Ng, T. K. T., Cheng, B. C. P., Chan, W. S., Lam, K. K., Chan, M. T. V.

“…Summary In a prospective, double‐blind, randomised controlled trial, we compared the efficacy of patient‐controlled analgesia using remifentanil (25–30 μg per…”
Get full text

Risks to healthcare workers following tracheal intubation of patients with COVID‐19: a prospective international multicentre cohort study by El‐Boghdadly, K., Wong, D. J. N., Owen, R., Neuman, M. D., Pocock, S., Carlisle, J. B., Johnstone, C., Andruszkiewicz, P., Baker, P. A., Biccard, B. M., Bryson, G. L., Chan, M. T. V., Cheng, M. H., Chin, K. J., Coburn, M., Jonsson Fagerlund, M., Myatra, S. N., Myles, P. S., O’Sullivan, E., Pasin, L., Shamim, F., van Klei, W. A., Ahmad, I.

“…Summary Healthcare workers involved in aerosol‐generating procedures, such as tracheal intubation, may be at elevated risk of acquiring COVID‐19. However, the…”
Get full text

A randomised comparison of InnoScope and Macintosh laryngoscope in simulated difficult tracheal intubation in manikins by Fong, A. W. Y., Lam, K. C., Cheng, B. C. P., Lam, K. K., Chan, M. T. V.

“…Summary We conducted a crossover randomised study to evaluate the performance of a novel optical stylet, the InnoScope, for tracheal intubation in simulated…”
Get full text

Aspirin in Patients Undergoing Noncardiac Surgery by Devereaux, P.J, Mrkobrada, Marko, Sessler, Daniel I, Leslie, Kate, Alonso-Coello, Pablo, Kurz, Andrea, Villar, Juan Carlos, Sigamani, Alben, Biccard, Bruce M, Meyhoff, Christian S, Parlow, Joel L, Guyatt, Gordon, Robinson, Andrea, Garg, Amit X, Rodseth, Reitze N, Botto, Fernando, Lurati Buse, Giovanna, Xavier, Denis, Chan, Matthew T.V, Tiboni, Maria, Cook, Deborah, Kumar, Priya A, Forget, Patrice, Malaga, German, Fleischmann, Edith, Amir, Mohammed, Eikelboom, John, Mizera, Richard, Torres, David, Wang, C.Y, VanHelder, Tomas, Paniagua, Pilar, Berwanger, Otavio, Srinathan, Sadeesh, Graham, Michelle, Pasin, Laura, Le Manach, Yannick, Gao, Peggy, Pogue, Janice, Whitlock, Richard, Lamy, André, Kearon, Clive, Baigent, Colin, Chow, Clara, Pettit, Shirley, Chrolavicius, Susan, Yusuf, Salim

“…In this trial, administering aspirin before surgery and during the early postsurgical period did not affect the rate of death or nonfatal MI but increased the…”
Get full text

Clonidine in Patients Undergoing Noncardiac Surgery by Devereaux, P.J, Sessler, Daniel I, Leslie, Kate, Kurz, Andrea, Mrkobrada, Marko, Alonso-Coello, Pablo, Villar, Juan Carlos, Sigamani, Alben, Biccard, Bruce M, Meyhoff, Christian S, Parlow, Joel L, Guyatt, Gordon, Robinson, Andrea, Garg, Amit X, Rodseth, Reitze N, Botto, Fernando, Lurati Buse, Giovanna, Xavier, Denis, Chan, Matthew T.V, Tiboni, Maria, Cook, Deborah, Kumar, Priya A, Forget, Patrice, Malaga, German, Fleischmann, Edith, Amir, Mohammed, Eikelboom, John, Mizera, Richard, Torres, David, Wang, C.Y, VanHelder, Tomas, Paniagua, Pilar, Berwanger, Otavio, Srinathan, Sadeesh, Graham, Michelle, Pasin, Laura, Le Manach, Yannick, Gao, Peggy, Pogue, Janice, Whitlock, Richard, Lamy, André, Kearon, Clive, Chow, Clara, Pettit, Shirley, Chrolavicius, Susan, Yusuf, Salim

“…In this trial, clonidine, an α2-adrenergic agonist, did not reduce the rate of death or MI among patients undergoing noncardiac surgery. Clonidine did increase…”
Get full text

Machine learning to predict myocardial injury and death after non‐cardiac surgery by Nolde, J. M., Schlaich, M. P., Sessler, D. I., Mian, A., Corcoran, T. B., Chow, C. K., Chan, M. T. V., Borges, F. K., McGillion, M. H., Myles, P. S., Mills, N. L., Devereaux, P. J., Hillis, G. S.

“…Summary Myocardial injury due to ischaemia within 30 days of non‐cardiac surgery is prognostically relevant. We aimed to determine the discrimination,…”
Get full text

Dreaming during anaesthesia in patients at high risk of awareness by Leslie, K., Myles, P. S., Forbes, A., Chan, M. T. V., Swallow, S. K., Short, T. G.

“…Summary Dreaming during anaesthesia is commonly reported but remains poorly understood. In this study, adult surgical patients at high risk of awareness were…”
Get full text

Recovery from bispectral index-guided anaesthesia in a large randomized controlled trial of patients at high risk of awareness by LESLIE, K, MYLES, P. S, FORBES, A, CHAN, M. T. V, SHORT, T. G, SWALLOW, S. K

“…Electroencephalographic monitors of anaesthetic depth are reported to assist anaesthetists in reducing recovery times. We explored the effect of bispectral…”
Get full text

Covert stroke after non-cardiac surgery: a prospective cohort study by Mrkobrada, M., Hill, M.D., Chan, M.T.V., Sigamani, A., Cowan, D., Kurz, A., Sessler, D.I., Jacka, M., Graham, M., Dasgupta, M., Dunlop, V., Emery, D.J., Gulka, I., Guyatt, G., Heels-Ansdell, D., Murkin, J., Pettit, S., Sahlas, D.J., Sharma, M., Srinathan, S., St John, P., Tsai, S., Gelb, A.W., O’Donnell, M., Siu, D., Chiu, P.W.Y., Sharath, V., George, A., Devereaux, P.J.

“…Overt stroke after non-cardiac surgery has a substantial impact on the duration and quality of life. Covert stroke in the non-surgical setting is much more…”
Get full text

Perioperative hypothermia and myocardial injury after non-cardiac surgery: abridged secondary publication by Chan, M T V, Lam, C K M, Cheng, B C P, Gin, T, Cheung, C W

Get full text

Effect of aspirin in vascular surgery in patients from a randomized clinical trial (POISE‐2) by Biccard, B. M., Sigamani, A., Chan, M. T. V., Sessler, D. I., Kurz, A., Tittley, J. G., Rapanos, T., Harlock, J., Szalay, D., Tiboni, M. E., Popova, E., Vásquez, S. M., Kabon, B., Amir, M., Mrkobrada, M., Mehra, B. R., El Beheiry, H., Mata, E., Tena, B., Sabaté, S., Zainal Abidin, M. K., Shah, V. R., Balasubramanian, K., Devereaux, P. J.

“…Background In the POISE‐2 (PeriOperative ISchemic Evaluation 2) trial, perioperative aspirin did not reduce cardiovascular events, but increased major…”
Get full text

Clinical diagnostic tools for screening of perioperative stroke in general surgery: a systematic review by Sun, Z., Yue, Y., Leung, C.C.H., Chan, M.T.V., Gelb, A.W.

“…Perioperative stroke is a devastating complication that carries high mortality and functional disability. Unfortunately, residual anaesthesia and analgesia may…”
Get full text

Chronic postsurgical pain in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II trial by Chan, M.T.V., Peyton, P.J., Myles, P.S., Leslie, K., Buckley, N., Kasza, J., Paech, M.J., Beattie, W.S., Sessler, D.I., Forbes, A., Wallace, S., Chen, Y., Tian, Y., Wu, W.K.K.

“…Previous animal and clinical studies showed that nitrous oxide may produce long-term analgesia. The aim of this study was to evaluate the effect of nitrous…”
Get full text

A randomised controlled trial of peri‐operative pregabalin vs. placebo for video‐assisted thoracoscopic surgery by Konstantatos, A. H., Howard, W., Story, D., Mok, L. Y. H., Boyd, D., Chan, M. T. V.

“…Summary We allocated 52 participants to oral pregabalin 300 mg and 48 participants to placebo tablets before thoracoscopic surgery and for five postoperative…”
Get full text

Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX) by Corcoran, T, Kasza, J, Short, T.G., O'Loughlin, E, Chan, M.T.V., Leslie, K, Forbes, A, Paech, M, Myles, P

“…In a post hoc analysis of the ENIGMA-II trial, we sought to determine whether intraoperative dexamethasone was associated with adverse safety outcomes. Inverse…”
Get full text

Mainstream vs. sidestream capnometry for prediction of arterial carbon dioxide tension during supine craniotomy by Chan, K. L., Chan, M. T. V., Gin, T.

“…Summary We compared the performance of mainstream capnometry as a measure of arterial carbon dioxide tension (Paco2) with sidestream recordings in adult…”
Get full text