Search Results - "Chan, M. Ete"

Vibration induced osteogenic commitment of mesenchymal stem cells is enhanced by cytoskeletal remodeling but not fluid shear by Uzer, Gunes, Pongkitwitoon, Suphannee, Ete Chan, M, Judex, Stefan

“…Abstract Consistent across studies in humans, animals and cells, the application of vibrations can be anabolic and/or anti-catabolic to bone. The physical…”
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Engineering anatomically shaped human bone grafts by Grayson, Warren L, Fröhlich, Mirjam, Yeager, Keith, Bhumiratana, Sarindr, Chan, M. Ete, Cannizzaro, Christopher, Wan, Leo Q, Liu, X. Sherry, Guo, X. Edward, Vunjak-Novakovic, Gordana

“…The ability to engineer anatomically correct pieces of viable and functional human bone would have tremendous potential for bone reconstructions after…”
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Low‐intensity vibration increases cartilage thickness in obese mice by Pamon, Tee, Bhandal, Vincent, Adler, Benjamin J., Ete Chan, M., Rubin, Clinton T.

“…ABSTRACT Obesity is associated with an elevated risk of osteoarthritis (OA). We examined here whether high fat diet administered in young mice, compromised the…”
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Marrow Adiposity and Hematopoiesis in Aging and Obesity: Exercise as an Intervention by Patel, Vihitaben S., Ete Chan, M., Rubin, Janet, Rubin, Clinton T.

“…Purpose of Review Changes in the bone marrow microenvironment, which accompany aging and obesity, including increased marrow adiposity, can compromise…”
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High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche by Adler, Benjamin J, Green, Danielle E, Pagnotti, Gabriel M, Chan, M Ete, Rubin, Clinton T

“…The bone marrow (BM) niche is the primary site of hematopoiesis, and cues from this microenvironment are critical to maintain hematopoiesis. Obesity increases…”
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Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma by Pagnotti, Gabriel M., Chan, M. Ete, Adler, Benjamin J., Shroyer, Kenneth R., Rubin, Janet, Bain, Steven D., Rubin, Clinton T.

“…Myeloma facilitates destruction of bone and marrow. Since physical activity encourages musculoskeletal preservation we evaluated whether low-intensity…”
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Postural Stability in Obese Preoperative Bariatric Patients Using Static and Dynamic Evaluation by Pagnotti, Gabriel M., Haider, Amna, Yang, Ariel, Cottell, Kathryn E., Tuppo, Catherine M., Tong, Kai-Yu, Pryor, Aurora D., Rubin, Clinton T., Chan, M. Ete

“…Introduction: Globally, 300 million adults have clinical obesity. Heightened adiposity and inadequate musculature secondary to obesity alter bipedal stance and…”
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Mechanical signals protect stem cell lineage selection, preserving the bone and muscle phenotypes in obesity by Frechette, Danielle M., Krishnamoorthy, Divya, Pamon, Tee, Chan, M. Ete, Patel, Vihitaben, Rubin, Clinton T.

“…The incidence of obesity is rapidly rising, increasing morbidity and mortality rates worldwide. Associated comorbidities include type 2 diabetes, heart…”
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Diminished satellite cells and elevated adipogenic gene expression in muscle as caused by ovariectomy are averted by low-magnitude mechanical signals by Frechette, Danielle M, Krishnamoorthy, Divya, Adler, Benjamin J, Chan, M Ete, Rubin, Clinton T

“…Age-related degeneration of the musculoskeletal system, accelerated by menopause, is further complicated by increased systemic and muscular adiposity. The…”
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Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer by Pagnotti, Gabriel M, Adler, Benjamin J, Green, Danielle E, Chan, M. Ete, Frechette, Danielle M, Shroyer, Kenneth R, Beamer, Wesley G, Rubin, Janet, Rubin, Clinton T

“…Abstract Cancer progression is often paralleled by a decline in bone mass, raising risk of fracture. Concerns persist regarding anabolic interventions for…”
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The association between sleeve gastrectomy and histopathologic changes consistent with esophagitis in a rodent model by Altieri, Maria S., M.D., M.S, Shroyer, Kenneth R., M.D., Ph.D, Pryor, Aurora, M.D, Pagnotti, Gabriel M., Ph.D, Ete Chan, M., Ph.D, Talamini, Mark, M.D, Telem, Dana A., M.D

“…Abstract Background As the association between sleeve gastrectomy (SG) and gastroesophageal reflux disease remains unclear, the aim of this study was to…”
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Separating Fluid Shear Stress from Acceleration during Vibrations In Vitro: Identification of Mechanical Signals Modulating the Cellular Response by Uzer, Gunes, Manske, Sarah L., Chan, M. Ete, Chiang, Fu-Pen, Rubin, Clinton T., Frame, Mary D., Judex, Stefan

“…The identification of the physical mechanism(s) by which cells can sense vibrations requires the determination of the cellular mechanical environment. Here, we…”
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Bone structure and B‐cell populations, crippled by obesity, are partially rescued by brief daily exposure to low‐magnitude mechanical signals by Chan, M. Ete, Adler, Benjamin J., Green, Danielle E., Rubin, Clinton T.

“…Deterioration of the immune and skeletal systems, each of which parallel obesity, reflects a fragile interrelationship between adiposity and osteoimmunology…”
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Incorporating Refractory Period in Mechanical Stimulation Mitigates Obesity‐Induced Adipose Tissue Dysfunction in Adult Mice by Patel, Vihitaben S., Chan, M. Ete, Pagnotti, Gabriel M., Frechette, Danielle M., Rubin, Janet, Rubin, Clinton T.

“…Objective The aim of this study was to determine whether inclusion of a refractory period between bouts of low‐magnitude mechanical stimulation (LMMS) can curb…”
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The Potential Benefits and Inherent Risks of Vibration as a Non-Drug Therapy for the Prevention and Treatment of Osteoporosis by Chan, M. Ete, Uzer, Gunes, Rubin, Clinton T.

“…The delivery of mechanical signals to the skeleton using vibration is being considered as a non-drug treatment of osteoporosis. Delivered over a range of…”
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Low intensity mechanical signals promote proliferation in a cell-specific manner: Tailoring a non-drug strategy to enhance biomanufacturing yields by Chan, M. Ete, Ashdown, Christopher, Strait, Lia, Pasumarthy, Sishir, Hassan, Abdullah, Crimarco, Steven, Singh, Chanpreet, Patel, Vihitaben S., Pagnotti, Gabriel, Khan, Omor, Uzer, Gunes, Rubin, Clinton T.

“…Biomanufacturing relies on living cells to produce biotechnology-based therapeutics, tissue engineering constructs, vaccines, and a vast range of agricultural…”
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Low Intensity Vibration Mitigates Tumor Progression and Protect Bone Quantity and Quality in a Murine Model of Myeloma by Pagnotti, Gabriel M, Chan, M. Ete, Adler, Benjamin J, Shroyer, Kenneth R, Rubin, Janet, Bain, Steven D, Rubin, Clinton T

“…Abstract Myeloma facilitates destruction of bone and marrow. Since physical activity encourages musculoskeletal preservation we evaluated whether low-intensity…”
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