Search Results - "Chan, Kwan L"

Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis by Capoulade, Romain, PhD, Chan, Kwan L., MD, Yeang, Calvin, MD, PhD, Mathieu, Patrick, MD, Bossé, Yohan, PhD, Dumesnil, Jean G., MD, Tam, James W., MD, Teo, Koon K., MBBCh, PhD, Mahmut, Ablajan, MD, MSc, Yang, Xiaohong, BSc, Witztum, Joseph L., MD, Arsenault, Benoit J., PhD, Després, Jean-Pierre, PhD, Pibarot, Philippe, DVM, PhD, Tsimikas, Sotirios, MD

“…Abstract Background Elevated lipoprotein(a) (Lp[a]) is associated with aortic stenosis (AS). Oxidized phospholipids (OxPL) are key mediators of calcification…”
Get full text

Lipid Lowering on Progression of Mild to Moderate Aortic Stenosis: Meta-analysis of the Randomized Placebo-Controlled Clinical Trials on 2344 Patients by Teo, Koon K., MB, PhD, Corsi, Daniel J., MSc, Tam, James W., MD, Dumesnil, Jean G., MD, Chan, Kwan L., MD

“…Abstract Background Aortic stenosis (AS) is believed to develop through an inflammatory similar to the atherosclerosis process. Based on findings from animal…”
Get full text

Circulating Levels of Matrix Gla Protein and Progression of Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) Trial by Capoulade, Romain, PhD, Côté, Nancy, PhD, Mathieu, Patrick, MD, FRCSC, Chan, Kwan L., MD, FRCPC, Clavel, Marie-Annick, DVM, PhD, Dumesnil, Jean G., MD, FRCPC, FACC, Teo, Koon K., MBBCh, PhD, FACC, Tam, James W., MD, FRCPC, Fournier, Dominique, MSc, Després, Jean-Pierre, PhD, FAHA, Pibarot, Philippe, DVM, PhD, FACC, FAHA

“…Abstract Background Matrix γ-carboxyglutamate protein is an inhibitor of cardiovascular calcification. The objective of this substudy of the Aortic Stenosis…”
Get full text

Impact of Metabolic Syndrome on Progression of Aortic Stenosis by Capoulade, Romain, MSc, Clavel, Marie-Annick, DVM, MSc, Dumesnil, Jean G., MD, Chan, Kwan L., MD, Teo, Koon K., MBBcH, PhD, Tam, James W., MD, Côté, Nancy, MSc, Mathieu, Patrick, MD, Després, Jean-Pierre, PhD, Pibarot, Philippe, DVM, PhD

“…Objectives The aims of this study were to examine prospectively the relationship between metabolic syndrome (MetS) and aortic stenosis (AS) progression and to…”
Get full text

Association of Mild to Moderate Aortic Valve Stenosis Progression With Higher Lipoprotein(a) and Oxidized Phospholipid Levels: Secondary Analysis of a Randomized Clinical Trial by Capoulade, Romain, Yeang, Calvin, Chan, Kwan L, Pibarot, Philippe, Tsimikas, Sotirios

“…Several studies have reported an association of levels of lipoprotein(a) (Lp[a]) and the content of oxidized phospholipids on apolipoprotein B (OxPL-apoB) and…”
Get more information

Unusual Cause of an Ejection Murmur: Myxoma in the Left Ventricular Outflow Tract by Rao, Rajeev V., MD, FRCPC, Walsh, Sam, BSc(Hon), Chan, Vincent, MD, FRCSC, Stadnick, Ellamae, MD, MSc, FRCPC, Sohmer, Benjamin, MD, FRCPC, Veinot, John P., MD, FRCPC, Chan, Kwan L., MD, FRCPC, FACC

“…Abstract We present the case of a healthy, asymptomatic 50-year-old woman with a systolic ejection murmur who was found to have an obstructive left ventricular…”
Get full text

Prevalence and Phenotypic Characterization of Patients with Bicuspid Aortic Valve and Large Aortic Annular Diameter by Higginson, Casey, Willner, Nadav, Petruescu, Laura, Beauchesne, Luc, Coutinho, Thais, Boodhwani, Munir, Chan, Kwan L., Burwash, Ian G., Messika-Zeitoun, David

Get full text

Cardiovascular Imaging: New Directions in an Evolving Landscape by Dwivedi, Girish, MD, MRCP(UK), PhD(UK), FASE, Chan, Kwan L., MD, FRCPC, FACC, Friedrich, Matthias G., MD, Beanlands, Rob S.B., MD, FRCPC, FACC

Get full text

Standards for Provision and Accreditation of Echocardiography in Ontario by Sanfilippo, Anthony J., MD, FRCP, FACC, Chan, Kwan L., MD, FRCPC, FAHA, FACC, Hughes, William G., MD, FRCPC, Kingsbury, Kori J., MPA, MSN, Leong-Poi, Howard, MD, FRCP, FASE, Sasson, Zion, MD, FRCP, FACC, Wald, Robert, MD, FRCP, FACC

“…Abstract In March of 2010, the Ontario Ministry of Health and Long-term Care and Ontario Medical Association jointly commissioned a Working Group to make…”
Get full text

Natural History of Mitral Annular Calcification and Calcific Mitral Valve Disease by Willner, Nadav, Burwash, Ian G., Beauchesne, Luc, Chan, Vince, Vulesevic, Branka, Ascah, Kathy, Coutinho, Thais, Promislow, Steve, Stadnick, Ellamae, Chan, Kwan L., Mesana, Thierry, Messika-Zeitoun, David

“…The natural history of mitral annular calcification (MAC) and risk for developing calcific mitral valve disease (CMVD) have been poorly defined. The aim of…”
Get full text

Challenges in the Evaluation of Aortic Stenosis: A Guide to Multimodal Imaging by Durr, Michael-Roy, Burwash, Ian G., Tavoosi, Anahita, Prosperi-Porta, Graeme, Santi, Nicolas, Unni, Rudy R., Lopez Laporte, Maria Agustina, Sharma, Arjun N., Aljamaan, Alwaleed, Paterson, Ian D., Chan, Kwan L., Andrew Mulloy, Luc Beauchesne, Alfraidi, Hassan, Lau, Lawrence, Froeschl, Michael, Messika-Zeitoun, David

“…Severe Aortic stenosis (AS) is characterised by a late peaking crescendo-decrescendo systolic murmur and a diminished/absent second heart sound…”
Get full text

Impact of Metabolic Syndrome on Progression of Aortic Stenosis: Influence of Age and Statin Therapy by CAPOULADE, Romain, CLAVEL, Marie-Annick, DUMESNIL, Jean G, CHAN, Kwan L, TEO, Koon K, TAM, James W, COTE, Nancy, MATHIEU, Patrick, DESPRES, Jean-Pierre, PIBAROT, Philippe

“…The aims of this study were to examine prospectively the relationship between metabolic syndrome (MetS) and aortic stenosis (AS) progression and to evaluate…”
Get full text

Size-adjusted aortic valve area: refining the definition of severe aortic stenosis by Vulesevic, Branka, Kubota, Naozumi, Burwash, Ian G, Cimadevilla, Claire, Tubiana, Sarah, Duval, Xavier, Nguyen, Virginia, Arangalage, Dimitri, Chan, Kwan L, Mulvihill, Erin E, Beauchesne, Luc, Messika-Zeitoun, David

“…Abstract Aims Severe aortic valve stenosis (AS) is defined by an aortic valve area (AVA) <1 cm2 or an AVA indexed to body surface area (BSA) <0.6 cm/m2,…”
Get full text

Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study by Jassal, Davinder S, Bhagirath, Kapil M, Karlstedt, Erin, Zeglinski, Matthew, Dumesnil, Jean G, Teo, Koon K, Tam, James W, Chan, Kwan L

“…Tissue Doppler imaging (TDI) is a noninvasive echocardiographic method for the diagnosis of diastolic dysfunction in patients with varying degrees of aortic…”
Get full text

Outcomes of Patients With Discordant High-Gradient Aortic Valve Stenosis by Vulesevic, Branka, Burwash, Ian G., Beauchesne, Luc M., Cimadevilla, Claire, Siouti, Leila, Tubiana, Sarah, Duval, Xavier, Nguyen, Virginia, Arangalage, Dimitri, Chan, Kwan L., Mulvihill, Erin E., Messika-Zeitoun, David

Get full text

Presentation and management of calcific mitral valve disease by Shamsudeen, Isabel, Fei, Linda Yi Ning, Burwash, Ian G., Beauchesne, Luc, Chan, Vincent, Glineur, David, Chan, Kwan L., Mesana, Thierry, Messika-Zeitoun, David

“…Little is known about the prevalence, presentation and management of calcific mitral valve disease (CMVD). We identified 167 patients (80 ± 10 years; 79%…”
Get full text

Coronary Artery Complications in Infective Endocarditis by Allan, Rebecca, MD, FRCPC, Hynes, Mark, MD, FRCPC, Burwash, Ian G., MD, FRCPC, Veinot, John P., MD, FRCPC, Chan, Kwan L., MD, FRCPC

Get full text

Tricuspid Annular Systolic Velocity Predicts Maximal Oxygen Consumption During Exercise in Adult Patients with Repaired Tetralogy of Fallot by Salehian, Omid, MD, MSc, FRCPC, FACC, Burwash, Ian G., MD, FRCPC, Chan, Kwan L., MD, MSc, FRCPC, FACC, Beauchesne, Luc M., MD, FRCPC, FACC

“…Background Many patients with repaired tetralogy of Fallot (TOF) have clinically important pulmonary regurgitation that can eventually lead to right…”
Get full text

Clinical Usefulness of Tissue Doppler Imaging in Patients with Mild to Moderate Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin Study by Jassal, Davinder S., MD, FRCPC, Tam, James W., MD, FRCPC, Dumesnil, Jean G., MD, FRCPC, Giannoccaro, Peter J., MD, FRCPC, Jue, John, MD, FRCPC, Pandey, A. Shekhar, MD, FRCPC, Joyner, Campbell D., MD, FRCPC, Teo, Koon K., MD, FRCPC, Chan, Kwan L., MD, FRCPC

“…Objective Although impaired diastolic function is common in aortic stenosis (AS), little is known about the clinical usefulness of tissue Doppler imaging (TDI)…”
Get full text

Clinical implications of left atrial size adjustment: Impact of obesity by Mulloy, Andrew, Siouti, Leila, Beauchesne, Luc, Chan, Kwan L., Vulesevic, Branka, Ascah, Kathy, Countinho, Thais, Promislow, Steve, Burwash, Ian G., Messika-Zeitoun, David

“…American and European societies recommend using left atrial (LA) volume adjusted to body surface area (BSA) as the means of indexing LA volume to the patient's…”
Get full text