Search Results - "Chan, Kun‐Wei"
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A site of vulnerability at V3 crown defined by HIV-1 bNAb M4008_N1
Published in Nature communications (09-11-2021)“…Identification of vulnerable sites defined by broadly neutralizing antibodies (bNAbs) on HIV-1 envelope (Env) is crucial for vaccine design, and we present…”
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2
Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes
Published in PLoS pathogens (28-12-2020)“…HIV-1 envelope (Env) is a trimer of gp120-gp41 heterodimers, synthesized from a precursor gp160 that contains an ER-targeting signal peptide (SP) at its…”
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Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains
Published in Nature communications (21-05-2024)“…The vaccine elicitation of HIV tier-2-neutralization antibodies has been a challenge. Here, we report the isolation and characterization of a CD4-binding site…”
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Mucosal Delivery of HIV‐1 Glycoprotein Vaccine Candidate Enabled by Short Carbon Nanotubes
Published in Particle & particle systems characterization (01-05-2022)“…The human immunodeficiency virus (HIV‐1) envelope glycoprotein spike is targeted by antibodies and therefore represents the main viral antigen for…”
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Bushmeat Species Identification: Recombinase Polymerase Amplification (RPA) Combined with Lateral Flow (LF) Strip for Identification of Formosan Reeves' Muntjac ( Muntiacus reevesi micrurus )
Published in Animals (Basel) (07-02-2021)“…The identification of animal species of meat in meat products is of great concern for various reasons, such as public health, religious beliefs, food…”
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Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection
Published in Journal of virology (15-09-2018)“…Elucidating the structural basis of antibody (Ab) gene usage and affinity maturation of vaccine-induced Abs can inform the design of immunogens for inducing…”
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Bacillus amyloliquefaciens CU33 Fermented Feather-Soybean Meal Product Improves the Crude Protein Digestibility, Diarrhea Status, and Growth Performance of Goat Kids
Published in Animals (Basel) (29-09-2024)“…This study investigates the effects of replacing fish meal with fermented feather meal-soybean meal product (FFSMP) from CU33 in the starter on growth…”
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Development of an antigen-capture ELISA for beak and feather disease virus
Published in Archives of virology (2018)“…Psittacine beak and feather disease (PBFD) is characterised by degenerative feather, feather dystrophy, and beak deformity. Sometimes acute forms can lead to…”
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High prevalence of caprine arthritis encephalitis virus (CAEV) in Taiwan revealed by large-scale serological survey
Published in Journal of Veterinary Medical Science (2017)“…In this study, a large-scale serological survey of caprine arthritis encephalitis virus (CAEV) infection was conducted between March 2011 and October 2012…”
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10
Clinical and Microbiological Features of Shewanella Bacteremia in Patients with Hepatobiliary Disease
Published in Internal Medicine (01-01-2013)“…Objective Shewanella bacteremia is an uncommon but potentially fatal disease. Although hepatobiliary diseases have been proposed to be risk factors for various…”
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Rapid immune colloidal gold strip for cetacean meat restraining illegal trade and consumption: implications for conservation and public health
Published in PloS one (28-03-2013)“…The consumption of cetacean meat is geographically common and often of undetermined sustainability. Besides, it can expose humans to contaminants and zoonotic…”
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12
Single-Stranded DNA-Binding Protein Complex from Helicobacter pylori Suggests an ssDNA-Binding Surface
Published in Journal of molecular biology (08-05-2009)“…Single-stranded DNA (ssDNA)-binding protein (SSB) plays an important role in DNA replication, recombination, and repair. SSB consists of an N-terminal…”
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Development of a loop-mediated isothermal amplification for rapid detection of orf virus
Published in Journal of virological methods (01-05-2009)“…A loop-mediated isothermal amplification (LAMP) assay using six primers targeting a highly conserved region of the B2L gene has been developed to diagnose orf…”
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14
Suppression of influenza virus infection by the orf virus isolated in Taiwan
Published in Journal of Veterinary Medical Science (01-09-2015)“…Orf virus (ORFV), a member of parapoxvirus, is an enveloped virus with genome of double-stranded DNA. ORFV causes contagious pustular dermatitis or contagious…”
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A rapid DNA amplification assay for cetacean product identification: Providing insights for illegal cetacean utilization and implications for conservation
Published in Ocean & coastal management (01-05-2024)“…Illegal utilization of cetaceans was continuously reported worldwide, posing potential threat to the sustainability of cetacean species. In addition, public…”
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The genotyping of Infectious bronchitis virus in Taiwan by a multiplex amplification refractory mutation system reverse transcription polymerase chain reaction
Published in Journal of veterinary diagnostic investigation (01-11-2014)“…Infectious bronchitis virus (IBV; Avian coronavirus) causes acute respiratory and reproductive and urogenital diseases in chickens. Following sequence…”
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Phylogenetic analysis of parapoxviruses and the C-terminal heterogeneity of viral ATPase proteins
Published in Gene (01-03-2009)“…Two outbreaks of orf virus (a parapoxvirus) infection in goats found in Nantou and Taiping of central Taiwan were investigated. The nucleotide and the amino…”
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Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-2024)“…Lymphocyte activation gene-3 (LAG-3) is an inhibitory receptor expressed on activated T cells and an emerging immunotherapy target. Domain 1 (D1) of LAG-3,…”
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Shewanella infection of snake bites: a twelve-year retrospective study
Published in Clinics (São Paulo, Brazil) (01-01-2012)“…Infections of snake bite wounds by Shewanella are rarely discussed in the medical literature. This study aims to characterize the presentation and management…”
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Antimicrobial resistance to cefotaxime and ertapenem in Enterobacteriaceae: the effects of altering clinical breakpoints
Published in Journal of infection in developing countries (13-03-2014)“…The Clinical and Laboratory Standards Institute (CLSI) updated its antimicrobial susceptibility testing interpretation criteria for Enterobacteriaceae. This…”
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