Search Results - "Chan, Kathleen L"

Antifungal Drug Repurposing by Kim, Jong H., Cheng, Luisa W., Chan, Kathleen L., Tam, Christina C., Mahoney, Noreen, Friedman, Mendel, Shilman, Mikhail Martchenko, Land, Kirkwood M.

“…Control of fungal pathogens is increasingly problematic due to the limited number of effective drugs available for antifungal therapy. Conventional antifungal…”
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Natural Salicylaldehyde for Fungal and Pre- and Post-Emergent Weed Control by Kim, Jong H., Chan, Kathleen L.

“…A sustainable, alternative weed control strategy is developed using salicylaldehyde (SA; 2-hydroxybenzaldehyde) as an active ingredient. SA is a natural,…”
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Chemosensitization as a means to augment commercial antifungal agents by Campbell, Bruce C, Chan, Kathleen L, Kim, Jong H

“…Antimycotic chemosensitization and its mode of action are of growing interest. Currently, use of antifungal agents in agriculture and medicine has a number of…”
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The Inhibitory Activity of Salicylaldehyde Compounds on Aspergillus Species and Their Effects on Aflatoxin Production and Crop Seed Germination by Kim, Jong H, Chan, Kathleen L, Hart-Cooper, William M, Ford, DeAngela, Orcutt, Kaydren, Sarreal, Siov Bouy L, Palumbo, Jeffrey D, Orts, William J

“…Crops such as tree nuts, corn and peanut are highly susceptible to infestation by the aspergilli Aspergillus flavus or Aspergillus parasiticus and subsequent…”
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Cinnamic Acid Analogs as Intervention Catalysts for Overcoming Antifungal Tolerance by Kim, Jong H, Chan, Kathleen L, Cheng, Luisa W

“…Disruption of fungal cell wall should be an effective intervention strategy. However, the cell wall-disrupting echinocandin drugs, such as caspofungin (CAS),…”
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Antimicrobial Efficacy of Edible Mushroom Extracts: Assessment of Fungal Resistance by Kim, Jong H., Tam, Christina C., Chan, Kathleen L., Mahoney, Noreen, Cheng, Luisa W., Friedman, Mendel, Land, Kirkwood M.

“…Antimicrobial efficacy of the water or methanolic extracts of three medicinal mushrooms Taiwanofungus camphoratus, Agaricus blazei Murrill, and Ganoderma…”
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Augmenting the Antifungal Activity of an Oxidizing Agent with Kojic Acid: Control of Penicillium Strains Infecting Crops by Kim, Jong H, Chan, Kathleen L

“…Oxidative treatment is one of the strategies for preventing Penicillium contamination in crops/foods. The antifungal efficacy of hydrogen peroxide (H2O2;…”
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Augmenting the Activity of Monoterpenoid Phenols against Fungal Pathogens Using 2-Hydroxy-4-methoxybenzaldehyde that Target Cell Wall Integrity by Kim, Jong H, Chan, Kathleen L, Mahoney, Noreen

“…Disruption of cell wall integrity system should be an effective strategy for control of fungal pathogens. To augment the cell wall disruption efficacy of…”
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High-efficiency fungal pathogen intervention for seed protection: new utility of long-chain alkyl gallates as heat-sensitizing agents by Kim, Jong H., Chan, Kathleen L., Hart-Cooper, William M., Palumbo, Jeffrey D., Orts, William J.

“…Control of food-contaminating fungi, especially pathogens that produce mycotoxins, is problematic since effective method for intervening fungal infection on…”
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Valorizing Tree-Nutshell Particles as Delivery Vehicles for a Natural Herbicide by Kim, Jong H, Chan, Kathleen L, Hart-Cooper, William M, Ford, DeAngela, Orcutt, Kaydren, Palumbo, Jeffrey D, Tam, Christina C, Orts, William J

“…The United States is a principal producer of tree nuts (almonds, pistachios, and walnuts), resulting in the generation of excess of tree-nutshell by-products…”
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Antifungal Efficacy of Redox-Active Natamycin against Some Foodborne Fungi—Comparison with Aspergillus fumigatus by Kim, Jong H., Tam, Christina C., Chan, Kathleen L., Cheng, Luisa W., Land, Kirkwood M., Friedman, Mendel, Chang, Perng-Kuang

“…The fungal antioxidant system is one of the targets of the redox-active polyene antifungal drugs, including amphotericin B (AMB), nystatin (NYS), and natamycin…”
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High Efficiency Drug Repurposing Design for New Antifungal Agents by Kim, Jong H, Chan, Kathleen L, Cheng, Luisa W, Tell, Lisa A, Byrne, Barbara A, Clothier, Kristin, Land, Kirkwood M

“…Current antifungal interventions have often limited efficiency in treating fungal pathogens, particularly those resistant to commercial drugs or fungicides…”
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Antifungal activity of redox-active benzaldehydes that target cellular antioxidation by Kim, Jong H, Chan, Kathleen L, Mahoney, Noreen, Campbell, Bruce C

“…Background: Disruption of cellular antioxidation systems should be an effective method for control of fungal pathogens. Such disruption can be achieved with…”
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Synergism of antifungal activity between mitochondrial respiration inhibitors and kojic acid by Kim, Jong H, Campbell, Bruce C, Chan, Kathleen L, Mahoney, Noreen, Haff, Ronald P

“…Co-application of certain types of compounds to conventional antimicrobial drugs can enhance the efficacy of the drugs through a process termed…”
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Enhancement of antimycotic activity of amphotericin B by targeting the oxidative stress response of Candida and cryptococcus with natural dihydroxybenzaldehydes by Kim, Jong H, Faria, Natália C G, Martins, M De L, Chan, Kathleen L, Campbell, Bruce C

“…In addition to the fungal cellular membrane, the cellular antioxidant system can also be a viable target in the antifungal action of amphotericin B (AMB)…”
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Crosstalk between the antioxidant and cell wall integrity systems in fungi by 2-hydroxy-4-methoxybenzaldehyde by Kim, Jong H., Chan, Kathleen L., Tam, Christina C., Cheng, Luisa W., Land, Kirkwood M.

“…We would like to comment on a recent study where the redox-modulatory anti-protozoal drug chloroquine has shown to trigger a crosstalk between the antioxidant…”
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Targeting the Mitochondrial Respiratory Chain of Cryptococcus through Antifungal Chemosensitization: A Model for Control of Non-Fermentative Pathogens by Kim, Jong H, Haff, Ronald P, Faria, Natália C.G, Martins, Maria de L, Chan, Kathleen L, Campbell, Bruce C

“…Enhanced control of species of Cryptococcus, non-fermentative yeast pathogens, was achieved by chemosensitization through co-application of certain compounds…”
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Enhancement of commercial antifungal agents by Kojic Acid by Kim, Jong H, Chang, Perng-Kuang, Chan, Kathleen L, Faria, Natália C G, Mahoney, Noreen, Kim, Young K, Martins, Maria de L, Campbell, Bruce C

“…Natural compounds that pose no significant medical or environmental side effects are potential sources of antifungal agents, either in their nascent form or as…”
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Chemosensitization of Aflatoxigenic Fungi to Antimycin A and Strobilurin Using Salicylaldehyde, a Volatile Natural Compound Targeting Cellular Antioxidation System by Kim, Jong H, Campbell, Bruce C, Mahoney, Noreen, Chan, Kathleen L, Molyneux, Russell J

“…Various species of fungi in the genus Aspergillus are the most common causative agents of invasive aspergillosis and/or producers of hepato-carcinogenic…”
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Rapid elimination of foodborne and environmental fungal contaminants by benzo analogs by Kim, Jong H, Chan, Kathleen L, Mahoney, Noreen, Cheng, Luisa W, Tautges, Nicole, Scow, Kate

“…BACKGROUND Contamination of food or the environment by fungi, especially those resistant to conventional fungicides or drugs, represents a hazard to human…”
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