Search Results - "Chan, Kannie Wy"
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GlucoCEST imaging with on‐resonance variable delay multiple pulse (onVDMP) MRI
Published in Magnetic resonance in medicine (01-01-2019)“…Purpose To examine the detection sensitivity for the rapidly exchanging hydroxyl protons of D‐glucose using the recently developed on‐resonance variable delay…”
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On‐resonance variable delay multipulse scheme for imaging of fast‐exchanging protons and semisolid macromolecules
Published in Magnetic resonance in medicine (01-02-2017)“…Purpose To develop an on‐resonance variable delay multipulse (VDMP) scheme to image magnetization transfer contrast (MTC) and the chemical exchange saturation…”
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Diamagnetic chemical exchange saturation transfer (diaCEST) liposomes: physicochemical properties and imaging applications
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-01-2014)“…Chemical exchange saturation transfer (CEST) is a new type of magnetic resonance imaging (MRI) contrast based on labile spins which rapidly exchange with…”
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Nuts and bolts of chemical exchange saturation transfer MRI
Published in NMR in biomedicine (01-07-2013)“…Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast mechanism that is well suited for molecular imaging studies. This new…”
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Dynamic glucose enhanced (DGE) MRI for combined imaging of blood-brain barrier break down and increased blood volume in brain cancer
Published in Magnetic resonance in medicine (01-12-2015)“…Purpose Recently, natural d‐glucose was suggested as a potential biodegradable contrast agent. The feasibility of using d‐glucose for dynamic perfusion imaging…”
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MRI-detectable pH nanosensors incorporated into hydrogels for in vivo sensing of transplanted-cell viability
Published in Nature materials (01-03-2013)“…Biocompatible nanomaterials and hydrogels have become an important tool for improving cell-based therapies by promoting cell survival and protecting cell…”
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D-Glucose uptake and clearance in the tauopathy Alzheimer’s disease mouse brain detected by on-resonance variable delay multiple pulse MRI
Published in Journal of cerebral blood flow and metabolism (01-05-2021)“…In this study, we applied on-resonance variable delay multiple pulse (onVDMP) MRI to study D-glucose uptake in a mouse model of Alzheimer’s disease (AD)…”
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Variable delay multi-pulse train for fast chemical exchange saturation transfer and relayed-nuclear overhauser enhancement MRI
Published in Magnetic resonance in medicine (01-05-2014)“…Purpose Chemical exchange saturation transfer (CEST) imaging is a new MRI technology allowing the detection of low concentration endogenous cellular proteins…”
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Characterization of tumor vascular permeability using natural dextrans and CEST MRI
Published in Magnetic resonance in medicine (01-02-2018)“…Purpose To investigate the use of natural dextrans as nano‐sized chemical exchange saturation transfer (CEST) MRI probes for characterizing size‐dependent…”
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An Ultrasound-activated Transdermal Patch for Closed-loop Diabetes Management System
Published in 2024 IEEE 3rd International Conference on Micro/Nano Sensors for AI, Healthcare, and Robotics (NSENS) (02-03-2024)“…Diabetes management is a multifaceted process that requires frequent monitoring and careful decision-making by the individual. However, due to inherent…”
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Conference Proceeding -
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Natural D-glucose as a biodegradable MRI relaxation agent
Published in Magnetic resonance in medicine (01-09-2014)“…Purpose Demonstrate applicability of natural D‐glucose as a T2 MRI contrast agent. Methods D‐glucose solutions were prepared at multiple concentrations and…”
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Enhanced angiogenesis in porous poly(ε-caprolactone) scaffolds fortified with methacrylated hyaluronic acid hydrogel after subcutaneous transplantation
Published in Biomaterials translational (2024)“…A composite scaffold composed of a porous scaffold and hydrogel filling can facilitate engraftment, survival, and retention in cell transplantation processes…”
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A diaCEST MRI approach for monitoring liposomal accumulation in tumors
Published in Journal of controlled release (28-04-2014)“…Nanocarrier-based chemotherapy allows preferential delivery of therapeutics to tumors and has been found to improve the efficacy of cancer treatment. However,…”
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P2‐377: IMPAIRED GLUCOSE UPTAKE IN MOUSE BRAIN WITH ALZHEIMER'S DISEASE DETECTED BY DYNAMIC GLUCOSE ENHANCED (DGE) MRI AT 3T
Published in Alzheimer's & dementia (01-07-2019)Get full text
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IMPAIRED GLUCOSE UPTAKE IN MOUSE BRAIN WITH ALZHEIMER’S DISEASE DETECTED BY DYNAMIC GLUCOSE ENHANCED (DGE) MRI AT 3T
Published in Alzheimer's & dementia (01-07-2019)Get full text
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Supercharged green fluorescent proteins as bimodal reporter genes for CEST MRI and optical imaging
Published in Chemical communications (Cambridge, England) (21-03-2015)“…Superpositively charged mutants of green fluorescent protein (GFP) demonstrated a dramatically improved chemical exchange saturation transfer (CEST) MRI…”
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Vaginal Delivery of Paclitaxel via Nanoparticles with Non-Mucoadhesive Surfaces Suppresses Cervical Tumor Growth
Published in Advanced healthcare materials (01-07-2014)“…Local delivery of chemotherapeutics in the cervicovaginal tract using nanoparticles may reduce adverse side effects associated with systemic chemotherapy,…”
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Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI
Published in Magnetic resonance in medicine (01-12-2013)“…Purpose To develop a noninvasive MRI method for determining the germination and infection of tumor‐homing bacteria in bacteriolytic cancer therapy using…”
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Non-invasive temperature mapping using temperature-responsive water saturation shift referencing (T-WASSR) MRI
Published in NMR in biomedicine (01-03-2014)“…We present a non‐invasive MRI approach for assessing the water proton resonance frequency (PRF) shifts associated with changes in temperature. This method is…”
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Microencapsulated cell tracking
Published in NMR in biomedicine (01-07-2013)“…Microencapsulation of therapeutic cells has been widely pursued to achieve cellular immunoprotection following transplantation. Initial clinical studies have…”
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Journal Article