Search Results - "Chan, Judy Yuet‐Wa"
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1
Evaluating Efficacy and Safety of Combination Medication of Atorvastatin and a Herbal Formula Containing Salvia miltiorrhiza and Pueraria lobata on Hyperlipidemia
Published in Phytotherapy research (01-10-2017)“…Despite being a potent hypolipidemic drug, atorvastatin (AS) possesses certain adverse effects. Using AS and an herbal formula (Danshen and Gegen, DG) in…”
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2
Evaluation in zebrafish model of the toxicity of rhodamine B‐conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics
Published in Journal of biochemical and molecular toxicology (01-11-2017)“…Crotamine is defensin‐like cationic peptide from rattlesnake venom that possesses anticancer, antimicrobial, and antifungal properties. Despite these promising…”
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3
Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo
Published in Journal of ethnopharmacology (01-09-2011)“…Angiogenesis, the process of blood vessel formation, is critical to tumour growth. The importance of angiogenesis in tumour development has lead to the…”
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4
Antihyperglycemic and antioxidative effects of a herbal formulation of Radix Astragali, Radix Codonopsis and Cortex Lycii in a mouse model of type 2 diabetes mellitus
Published in Phytotherapy research (01-05-2009)“…There is emerging evidence that the generation of reactive oxygen species (ROS), which leads to dysfunction of pancreatic β-cells, is a major factor in the…”
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5
Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis
Published in European journal of pharmacology (05-10-2012)“…Venenum Bufonis, a traditional Chinese medicine, is widely used in the treatment of liver cancer in modern Chinese medical practices. In our search for…”
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6
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells
Published in Journal of cellular biochemistry (01-01-2016)“…ABSTRACT Doxorubicin (Dox) is an anthracycline antibiotic widely used in clinics as an anticancer agent. However, the use of Dox is limited by its…”
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7
Altered Gut Microbiome and Environmental Factors Associated with Development of Eczema in Hong Kong Infants: A 4-Month Pilot Study
Published in International journal of environmental research and public health (20-10-2020)“…Eczema is a multifactorial skin disease that affects 20% of children worldwide and has a complex relationship with microbial, nutritional, parental and…”
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Structural characterization and immunomodulatory effect of a polysaccharide HCP-2 from Houttuynia cordata
Published in Carbohydrate polymers (15-03-2014)“…•A pure pectic polysaccharide (named HCP-2) was obtained from the water extract of Houttuynia cordata.•HCP-2 was chemically characterized using acid…”
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9
Hypericin and Pheophorbide a Mediated Photodynamic Therapy Fighting MRSA Wound Infections: A Translational Study from In Vitro to In Vivo
Published in Pharmaceutics (03-09-2021)“…High prevalence rates of methicillin-resistant Staphylococcus aureus (MRSA) and lack of effective antibacterial treatments urge discovery of alternative…”
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10
Isolation of Anti-Inflammatory Fractions and Compounds from the Root of Astragalus membranaceus
Published in Phytotherapy research (01-04-2013)“…Foot ulceration, if not treated properly, will eventually result in amputation. Inflammation may impede the wound healing process if not properly controlled…”
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11
Anti‐inflammatory Activities of an Active Fraction Isolated from the root of Astragalus membranaceus in RAW 264.7 Macrophages
Published in Phytotherapy research (01-03-2014)“…The root of Astragalus membranaceus (AR), which has been widely used in Traditional Chinese herbal formulae for treating foot ulcer, was found to exhibit…”
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12
Effects of polyphyllin D, a steroidal saponin in Paris Polyphylla, in growth inhibition of human breast cancer cells and in xenograft
Published in Cancer biology & therapy (01-11-2005)“…Paris Polyphylla is a traditional Chinese Medical herb that has been used in treating cancer for thousands of year. Without studies on the anticancer effects…”
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13
New perspective on the dual functions of indirubins in cancer therapy and neuroprotection
Published in Anti-cancer agents in medicinal chemistry (01-01-2014)“…Indirubin is an active ingredient mainly used to treat leukemia in China and is reported to be a leading inhibitor of cyclindependent kinases (CDKs) and…”
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14
Photodynamic Therapy of Pheophorbide a Inhibits the Proliferation of Human Breast Tumour via Both Caspase‐dependent and ‐independent Apoptotic Pathways in In Vitro and In Vivo Models
Published in Phytotherapy research (01-05-2012)“…Breast cancer is conventionally treated by surgery and radiotherapy, with adjuvant chemotherapy and hormonotherapy as supplementary treatments. However, such…”
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15
Antidiabetic Effect of Schisandrae Chinensis Fructus Involves Inhibition of the Sodium Glucose Cotransporter
Published in Drug development research (01-02-2015)“…Preclinical Research Schisandrae Chinensis Fructus (SCF), the fruit of Schisandra chinensis (Turcz.) Baill. (family Schisandraceae) is traditionally used as a…”
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Pheophorbide a, an active compound isolated from Scutellaria barbata, possesses photodynamic activities by inducing apoptosis in human hepatocellular carcinoma
Published in Cancer biology & therapy (01-09-2006)“…Photodynamic therapy (PDT) is an effective treatment for cancer by inducing apoptosis or necrosis in the target cells. Pheophorbide a (Pa), a chlorophyll…”
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17
Protective effects of an herbal formulation of Radix Astragali, Radix Codonopsis and Cortex Lycii on streptozotocin-induced apoptosis in pancreatic β-cells: an implication for its treatment of diabetes mellitus
Published in Phytotherapy research (01-02-2008)“…Hyperglycemia is one of the main causes of oxidative stress in type 2 diabetes mellitus. During hyperglycemia, the increased level of various reducing sugars…”
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18
Transcriptional analysis of doxorubicin-induced cytotoxicity and resistance in human hepatocellular carcinoma cell lines
Published in Liver international (01-10-2009)“…Background/Aims: Hepatoma is either intrinsically resistant to chemotherapy or response to it but later develop resistance. The aim of this study was to…”
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Complexation of clofazimine by macrocyclic cucurbit[7]uril reduced its cardiotoxicity without affecting the antimycobacterial efficacy
Published in Organic & biomolecular chemistry (01-01-2016)“…Cucurbit[7]uril (CB[7]) has recently attracted increasing attention in pharmaceutical sciences due to its great potential in improving the physicochemical…”
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20
Angiogenic effects of danshen and gegen decoction on human endothelial cells and zebrafish embryos
Published in The American journal of Chinese medicine (1979) (2013)“…Coronary artery diseases (CAD) are the most common diseases worldwide. Despite improvements in standard heart surgeries, many patients still progress to…”
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