Search Results - "Chan, I. S. F."

Persistence of the Efficacy of Zoster Vaccine in the Shingles Prevention Study and the Short-Term Persistence Substudy by Schmader, K. E., Oxman, M. N., Levin, M. J., Johnson, G., Zhang, J. H., Betts, R., Morrison, V. A., Gelb, L., Guatelli, J. C., Harbecke, R., Pachucki, C., Keay, S., Menzies, B., Griffin, M. R., Kauffman, C., Marques, A., Toney, J., Keller, P. M., Li, X., Chan, I. S. F., Annunziato, P.

“…Background. The Shingles Prevention Study (SPS; Department of Veterans Affairs Cooperative Study 403) demonstrated that zoster vaccine was efficacious through…”
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Varicella-Zoster Virus–Specific Immune Responses in Elderly Recipients of a Herpes Zoster Vaccine by Levin, M. J., Oxman, M. N., J. H. Zhang, Johnson, G. R., Stanley, H., Hayward, A. R., Caulfield, M. J., Irwin, M. R., Smith, J. G., Clair, J., Chan, I. S. F., Williams, H., Harbecke, R., Marchese, R., Straus, S. E., Gershon, A., Weinberg, A.

“…BackgroundA double-blind, placebo-controlled trial that involved 38,546 subjects ⩾60 years old demonstrated efficacy of a high-potency live-attenuated…”
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Efficacy, Safety, and Tolerability of Herpes Zoster Vaccine in Persons Aged 50—59 Years by Schmader, Kenneth E., Levin, Myron J., Gnann, John W., McNeil, Shelly A., Vesikari, Timo, Betts, Robert F., Keay, Susan, Stek, Jon E., Bundick, Nickoya D., Su, Shu-Chih, Zhao, Yanli, Li, Xiaoming, Chan, Ivan S. F., Annunziato, Paula W., Parrino, Janie

“…Background. Herpes zoster (HZ) adversely affects individuals aged 50—59, but vaccine efficacy has not been assessed in this population. This study was designed…”
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Statistical Considerations for NonInferiority/Equivalence Trials in Vaccine Development by Wang, W. W. B., Mehrotra, D. V., Chan, I. S. F., Heyse, J. F.

“…Noninferiority/equivalence designs are often used in vaccine clinical trials. The goal of these designs is to demonstrate that a new vaccine, or new…”
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Proving non-inferiority or equivalence of two treatments with dichotomous endpoints using exact methods by Chan, I SF

“…Since the early work of RA Fisher, exact methods have been recognized as important tools in data analysis because they provide valid statistical inference even…”
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A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women by Joura, Elmar A, Giuliano, Anna R, Iversen, Ole-Erik, Bouchard, Celine, Mao, Constance, Mehlsen, Jesper, Moreira, Edson D, Ngan, Yuen, Petersen, Lone Kjeld, Lazcano-Ponce, Eduardo, Pitisuttithum, Punnee, Restrepo, Jaime Alberto, Stuart, Gavin, Woelber, Linn, Yang, Yuh Cheng, Cuzick, Jack, Garland, Suzanne M, Huh, Warner, Kjaer, Susanne K, Bautista, Oliver M, Chan, Ivan S.F, Chen, Joshua, Gesser, Richard, Moeller, Erin, Ritter, Michael, Vuocolo, Scott, Luxembourg, Alain

“…The quadrivalent human papillomavirus vaccine is effective in preventing infection and disease related to HPV types 6, 11, 16, and 18. This phase 3 trial…”
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A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults by Oxman, M.N, Levin, M.J, Johnson, G.R, Schmader, K.E, Straus, S.E, Gelb, L.D, Arbeit, R.D, Simberkoff, M.S, Gershon, A.A, Davis, L.E, Weinberg, A, Boardman, K.D, Williams, H.M, Zhang, J. Hongyuan, Peduzzi, P.N, Beisel, C.E, Morrison, V.A, Guatelli, J.C, Brooks, P.A, Kauffman, C.A, Pachucki, C.T, Neuzil, K.M, Betts, R.F, Wright, P.F, Griffin, M.R, Brunell, P, Soto, N.E, Marques, A.R, Keay, S.K, Goodman, R.P, Cotton, D.J, Gnann, J.W, Loutit, J, Holodniy, M, Keitel, W.A, Crawford, G.E, Yeh, S.-S, Lobo, Z, Toney, J.F, Greenberg, R.N, Keller, P.M, Harbecke, R, Hayward, A.R, Irwin, M.R, Kyriakides, T.C, Chan, I.S.F, Chan, C.Y, Wang, W.W.B, Annunziato, P.W, Silber, J.L

“…Herpes zoster and postherpetic neuralgia occur more often with increasing age. In this controlled trial among 38,546 adults 60 years of age or older,…”
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Varicella Zoster Virus—Specific Immune Responses to a Herpes Zoster Vaccine in Elderly Recipients With Major Depression and the Impact of Antidepressant Medications by Irwin, Michael R., Levin, Myron J., Laudenslager, Mark L., Olmstead, Richard, Lucko, Anne, Lang, Nancy, Carrillo, Carmen, Stanley, Harold A., Caulfield, Michael J., Weinberg, Adriana, Chan, Ivan S. F., Clair, Jim, Smith, Jeff G., Marchese, R. D., Williams, Heather M., Beck, Danielle J., McCook, Patricia T., Zhang, Jane H., Johnson, Gary, Oxman, Michael N.

“…Background. The Depression Substudy of the Shingles Prevention Study (SPS) was designed to evaluate the association between major depression and immune…”
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Treatment comparisons with screenable endpoints by Chan, I.S.F., Hillman, D., Louis, T.A.

“…This paper proposes a method for treatment whmparison when the disease endpoint can be discovered by either screening or clinical surfacing. Assuming a zero…”
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Reply to Arroyo by Schmader, K. E., Levin, M. J., Keay, S., Chan, I. S. F., Annunziato, P. W., Parrino, J.

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Exact tests of equivalence and efficacy with a non-zero lower bound for comparative studies by Chan, Ivan S. F.

“…Exact tests of equivalence and efficacy with a non‐zero lower bound based on two independent binomial proportions for comparative trials are proposed. These…”
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Exact power and sample size for vaccine efficacy studies by Chan, Ivan S.F., Bohidar, Norman R.

“…In vaccine efficacy studies the goal is to show that the vaccine reduces the incidence of the disease compared to placebo. In this report we describe two…”
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A Dose Response Study of Hepatitis A Vaccine in Healthy Adults Who Are ≥30 Years Old and Weigh ≥77 kg by Bertino, Joseph S., Thoelen, Stefan, VanDamme, Pierre, Bryan, Joe P., Becherer, Paul R., Frey, Sharon, Hayden, Fredrick G., Marcus, Leonard C., Parenti, David M., Sperling, Malcolm, Chan, Ivan S. F., Brown, Leora, Nalin, David

“…The dose response relationship of 25-, 50-, and 100-U doses of an inactivated hepatitis A vaccine was examined in 358-seronegative volunteers in a 2-dose…”
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