Search Results - "Chan, Gina"
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Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (01-11-2006)“…Using in vitro drug sensitivity data coupled with Affymetrix microarray data, we developed gene expression signatures that predict sensitivity to individual…”
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Journal Article -
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An Integrated Genomic-Based Approach to Individualized Treatment of Patients With Advanced-Stage Ovarian Cancer
Published in Journal of clinical oncology (10-02-2007)“…The purpose of this study was to develop an integrated genomic-based approach to personalized treatment of patients with advanced-stage ovarian cancer. We have…”
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Journal Article -
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'My Parents told us that they will always Treat my Brother Differently Because he is Autistic' - Are Siblings of Autistic Children the Forgotten Ones?
Published in Journal of social work practice (03-04-2014)“…Autism spectrum disorder (ASD) does not only affect the child alone, but the family unit as well. This qualitative study explored the impacts of ASD on the…”
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Epigenetic Blocking of an Enhancer Region Controls Irradiation-Induced Proapoptotic Gene Expression in Drosophila Embryos
Published in Developmental cell (01-04-2008)“…Drosophila embryos are highly sensitive to γ-ray-induced apoptosis at early but not later, more differentiated stages during development. Two proapoptotic…”
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Journal Article -
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MicroRNAs and their target messenger RNAs associated with ovarian cancer response to chemotherapy
Published in Gynecologic oncology (01-05-2009)“…Abstract Objective Few successful therapeutic options exist for patients with recurrent ovarian cancer (OVCA). This is due in part to an incomplete…”
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Patient reported outcomes (PROs) in patients with human papilloma virus (HPV) positive versus negative head and neck cancer (HNC)
Published in Journal of clinical oncology (09-10-2016)“…Abstract only 87 Background: HNC caused by HPV has become an epidemic. Treatment for HNC results in a tremendous symptom burden. The impact of HPV-status on…”
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A two-group study to evaluate the impact of an educational handbook in the care of patients with head and neck cancer (HNC)
Published in Journal of clinical oncology (09-10-2016)“…Abstract only 228 Background: Patients undergoing chemoradiotherapy for HNC have a significant symptom burden, psychological distress, and educational needs…”
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Retraction: Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (01-01-2011)Get full text
Journal Article -
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The role of epithelial mesenchymal transition transcription factors on dna damage response
Published 01-01-2016“…The role of epithelial mesenchymal transition (EMT) has been identified to influence many processes associated with cancer development; malignant…”
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Dissertation -
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Retraction Note: Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (07-01-2011)“…The authors wish to retract this article because they have been unable to reproduce certain crucial experiments showing validation of signatures for predicting…”
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Journal Article -
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Michelob_x is the missing inhibitor of apoptosis protein antagonist in mosquito genomes
Published in EMBO reports (01-08-2005)“…Apoptosis is implicated in the life cycle of the malaria parasite in mosquitoes. The genome project for the primary malaria vector Anopheles gambiae showed a…”
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Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (01-08-2008)Get full text
Journal Article -
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Corrigendum: Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (01-08-2008)Get full text
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Erratum: Corrigendum: Genomic signatures to guide the use of chemotherapeutics
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Journal Article -
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Correction: Corrigendum: Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (2008)“…Nat. Med. 12, 1294–1300 (2006); published online 22 October 2006; corrected after print 10 May and 10 October 2007 and 18 July 2008 In the version of this…”
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Corrigenda: Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (01-11-2007)Get full text
Journal Article -
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Erratum: Corrigenda: Genomic signatures to guide the use of chemotherapeutics
Published in Nature medicine (01-11-2007)Get full text
Journal Article -
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Do Enzymes Change the Nature of Transition States? Mapping the Transition State for General Acid−Base Catalysis of a Serine Protease
Published in Biochemistry (Easton) (16-09-2003)“…The properties of the transition state for serine protease-catalyzed hydrolysis of an amide bond were determined for a series of subtilisin variants from…”
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Journal Article -
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Cyber insecurity
Published in The Financial times (London ed.) (15-07-2015)“…This first article of a series on the challenges facing the US government agencies' cyber security. The large number of breaches by hackers points to the lack…”
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Newspaper Article