Search Results - "Chan, Candace S.Y."

A survey of k-mer methods and applications in bioinformatics by Moeckel, Camille, Mareboina, Manvita, Konnaris, Maxwell A., Chan, Candace S.Y., Mouratidis, Ioannis, Montgomery, Austin, Chantzi, Nikol, Pavlopoulos, Georgios A., Georgakopoulos-Soares, Ilias

“…The rapid progression of genomics and proteomics has been driven by the advent of advanced sequencing technologies, large, diverse, and readily available omics…”
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kmerDB: A database encompassing the set of genomic and proteomic sequence information for each species by Mouratidis, Ioannis, Baltoumas, Fotis A., Chantzi, Nikol, Patsakis, Michail, Chan, Candace S.Y., Montgomery, Austin, Konnaris, Maxwell A., Aplakidou, Eleni, Georgakopoulos, George C., Das, Anshuman, Chartoumpekis, Dionysios V., Kovac, Jasna, Pavlopoulos, Georgios A., Georgakopoulos-Soares, Ilias

“…The decrease in sequencing expenses has facilitated the creation of reference genomes and proteomes for an expanding array of organisms. Nevertheless, no…”
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Peptide absent sequences emerging in human cancers by Tsiatsianis, Georgios Christos, Chan, Candace S Y, Mouratidis, Ioannis, Chantzi, Nikol, Tsiatsiani, Anna Maria, Yee, Nelson S, Zaravinos, Apostolos, Kantere, Verena, Georgakopoulos-Soares, Ilias

“…Early diagnosis of cancer can significantly improve survival of cancer patients; however sensitive and highly specific biomarkers for cancer detection are…”
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High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation by Georgakopoulos-Soares, Ilias, Chan, Candace S. Y., Ahituv, Nadav, Hemberg, Martin

“…The most stable structure of DNA is the canonical right-handed double helix termed B DNA. However, certain environments and sequence motifs favor alternative…”
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Transcription factor binding site orientation and order are major drivers of gene regulatory activity by Georgakopoulos-Soares, Ilias, Deng, Chengyu, Agarwal, Vikram, Chan, Candace S. Y., Zhao, Jingjing, Inoue, Fumitaka, Ahituv, Nadav

“…The gene regulatory code and grammar remain largely unknown, precluding our ability to link phenotype to genotype in regulatory sequences. Here, using a…”
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Functional characterization of Alzheimer’s disease genetic variants in microglia by Yang, Xiaoyu, Wen, Jia, Yang, Han, Jones, Ian R., Zhu, Xiaodong, Liu, Weifang, Li, Bingkun, Clelland, Claire D., Luo, Wenjie, Wong, Man Ying, Ren, Xingjie, Cui, Xiekui, Song, Michael, Liu, Hongjiang, Chen, Cady, Eng, Nicolas, Ravichandran, Mirunalini, Sun, Yang, Lee, David, Van Buren, Eric, Jiang, Min-Zhi, Chan, Candace S. Y., Ye, Chun Jimmie, Perera, Rushika M., Gan, Li, Li, Yun, Shen, Yin

“…Candidate cis -regulatory elements (cCREs) in microglia demonstrate the most substantial enrichment for Alzheimer’s disease (AD) heritability compared to other…”
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Cell type- and stage-specific expression of Otx2 is regulated by multiple transcription factors and cis -regulatory modules in the retina by Chan, Candace S Y, Lonfat, Nicolas, Zhao, Rong, Davis, Alexander E, Li, Liang, Wu, Man-Ru, Lin, Cheng-Hui, Ji, Zhe, Cepko, Constance L, Wang, Sui

“…Transcription factors (TFs) are often used repeatedly during development and homeostasis to control distinct processes in the same and/or different cellular…”
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Frequentmers - a novel way to look at metagenomic next generation sequencing data and an application in detecting liver cirrhosis by Mouratidis, Ioannis, Chantzi, Nikol, Khan, Umair, Konnaris, Maxwell A, Chan, Candace S Y, Mareboina, Manvita, Moeckel, Camille, Georgakopoulos-Soares, Ilias

“…Early detection of human disease is associated with improved clinical outcomes. However, many diseases are often detected at an advanced, symptomatic stage…”
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Utilizing nullomers in cell-free RNA for early cancer detection by Montgomery, Austin, Tsiatsianis, Georgios Christos, Mouratidis, Ioannis, Chan, Candace S. Y., Athanasiou, Maria, Papanastasiou, Anastasios D., Kantere, Verena, Syrigos, Nikos, Vathiotis, Ioannis, Syrigos, Konstantinos, Yee, Nelson S., Georgakopoulos-Soares, Ilias

“…Early detection of cancer can significantly improve patient outcomes; however, sensitive and highly specific biomarkers for cancer detection are currently…”
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Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain by Lin, Cheng-Hui, Sun, Yue, Chan, Candace S.Y., Wu, Man-Ru, Gu, Lei, Davis, Alexander E., Gu, Baokun, Zhang, Wenlin, Tanasa, Bogdan, Zhong, Lei R., Emerson, Mark M., Chen, Lu, Ding, Jun B., Wang, Sui

“…Adeno-associated viruses (AAVs) targeting specific cell types are powerful tools for studying distinct cell types in the central nervous system (CNS)…”
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Quasi-prime peptides: identification of the shortest peptide sequences unique to a species by Mouratidis, Ioannis, Chan, Candace S Y, Chantzi, Nikol, Tsiatsianis, Georgios Christos, Hemberg, Martin, Ahituv, Nadav, Georgakopoulos-Soares, Ilias

“…Abstract Determining the organisms present in a biosample has many important applications in agriculture, wildlife conservation, and healthcare. Here, we…”
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