Search Results - "Chan, Barbara Pui"

Parallel, Multi‐Material Electrohydrodynamic 3D Nanoprinting by Chen, Mojun, Lee, Heekwon, Yang, Jihyuk, Xu, Zhaoyi, Huang, Nan, Chan, Barbara Pui, Kim, Ji Tae

“…Direct mass‐transfer via liquid nanodroplets is one of the most powerful approaches for additive micro/nanofabrication. Electrohydrodynamic (EHD) dispensing…”
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A Structurally and Functionally Biomimetic Biphasic Scaffold for Intervertebral Disc Tissue Engineering by Choy, Andrew Tsz Hang, Chan, Barbara Pui

“…Tissue engineering offers high hopes for the treatment of intervertebral disc (IVD) degeneration. Whereas scaffolds of the disc nucleus and annulus have been…”
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Scaffold composition affects cytoskeleton organization, cell–matrix interaction and the cellular fate of human mesenchymal stem cells upon chondrogenic differentiation by Li, Yuk Yin, Choy, Tze Hang, Ho, Fu Chak, Chan, Pui Barbara

“…Abstract The stem cell niche, or microenvironment, consists of soluble, matrix, cell and mechanical factors that together determine the cellular fates and/or…”
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Extracellular Protease Inhibition Alters the Phenotype of Chondrogenically Differentiating Human Mesenchymal Stem Cells (MSCs) in 3D Collagen Microspheres by Han, Sejin, Li, Yuk Yin, Chan, Barbara Pui

“…Matrix remodeling of cells is highly regulated by proteases and their inhibitors. Nevertheless, how would the chondrogenesis of mesenchymal stem cells (MSCs)…”
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Microencapsulation of Neuroblastoma Cells and Mesenchymal Stromal Cells in Collagen Microspheres: A 3D Model for Cancer Cell Niche Study by Yeung, Pan, Sin, Hoi Shun, Chan, Shing, Chan, Godfrey Chi Fung, Chan, Barbara Pui

“…There is a growing trend for researchers to use in vitro 3D models in cancer studies, as they can better recapitulate the complex in vivo situation. And the…”
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Stiffness‐Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory by Fan, Xingliang, Zhu, Lu, Wang, Ke, Wang, Bingjie, Wu, Yaozu, Xie, Wei, Huang, Chengyu, Chan, Barbara Pui, Du, Yanan

“…Most mechanobiological investigations focused on in situ mechanical regulation of cells on stiffness‐controlled substrates with few downstream applications, as…”
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Mechanoresponsive, omni-directional and local matrix-degrading actin protrusions in human mesenchymal stem cells microencapsulated in a 3D collagen matrix by Ho, Fu Chak, Zhang, Wei, Li, Yuk Yin, Chan, Barbara Pui

“…Abstract Cells are known to respond to multiple niche signals including extracellular matrix and mechanical loading. In others and our own studies, mechanical…”
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Physical Properties of Implanted Porous Bioscaffolds Regulate Skin Repair: Focusing on Mechanical and Structural Features by Jiang, Shumeng, Li, Sabrina Cloud, Huang, Chenyu, Chan, Barbara Pui, Du, Yanan

“…Porous bioscaffolds are applied to facilitate skin repair since the early 1990s, but a perfect regeneration outcome has yet to be achieved. Until now, most…”
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Correction: Loading-Induced Heat-Shock Response in Bovine Intervertebral Disc Organ Culture by Chooi, Wai Hon, Chan, Samantha Chun Wai, Gantenbein, Benjamin, Chan, Barbara Pui

“…[This corrects the article DOI: 10.1371/journal.pone.0161615.]…”
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Loading-Induced Heat-Shock Response in Bovine Intervertebral Disc Organ Culture by Chooi, Wai Hon, Chan, Samantha Chun Wai, Gantenbein, Benjamin, Chan, Barbara Pui

“…Mechanical loading has been shown to affect cell viability and matrix maintenance in the intervertebral disc (IVD) but there is no investigation on how cells…”
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Bioengineering a Multicomponent Spinal Motion Segment Construct-A 3D Model for Complex Tissue Engineering by Chik, Tsz Kit, Chooi, Wai Hon, Li, Yuk Yin, Ho, Fu Chak, Cheng, Hiu Wa, Choy, Tsz Hang, Sze, Kam Yim, Luk, Keith Kei Dip, Cheung, Kenneth Man Chi, Chan, Barbara Pui

“…Intervertebral disc degeneration is an important clinical problem but existing treatments have significant drawbacks. The ability to bioengineer the entire…”
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A 3D micro-printed single cell micro-niche with asymmetric niche signals – An in vitro model for asymmetric cell division study by Huang, Nan, Chan, Barbara Pui

“…Intricate microenvironment signals orchestrate to affect cell behavior and fate during tissue morphogenesis. However, the underlying mechanisms on how specific…”
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Effect of Dexamethasone on Cultured Human Tenocytes and Its Reversibility by Platelet-Derived Growth Factor by Wong, Margaret Wan Nar, Tang, Yvonne Yin Nei, Lee, Simon Kwong Man, Fu, Bruma Sai Chuen, Chan, Barbara Pui, Chan, Cavor Kai Ming

“…BackgroundMany cases of tendon rupture after glucocorticoid injections have been reported in the literature. Despite previous studies on the histological and…”
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A Bio‐Functional Wnt3a Gradient Microarray for Cell Niche Studies by Wang, Xinna, Ou, Wanjing, Feng, Di, Gao, Bo, Chan, Barbara Pui

“…The Wingless/Integrated (Wnt) signaling is a central player in regulating multiple cellular events ranging from developmental process, adult homeostasis to…”
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Both non-coated and polyelectrolytically-coated intraocular collagen-alginate composite gels enhanced photoreceptor survival in retinal degeneration by Wong, Francisca Siu Yin, Tsang, Ken Kin, Chan, Barbara Pui, Lo, Amy Cheuk Yin

“…Treatments of vision-threatening retinal diseases are often hampered by drug delivery difficulties. Polyelectrolytically-coated alginate encapsulated-cell…”
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Compression loading-induced stress responses in intervertebral disc cells encapsulated in 3D collagen constructs by Chooi, Wai Hon, Chan, Barbara Pui

“…Cells protect themselves from stresses through a cellular stress response. In the interverebral disc, such response was also demonstrated to be induced by…”
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Collagen microencapsulation recapitulates mesenchymal condensation and potentiates chondrogenesis of human mesenchymal stem cells – A matrix-driven in vitro model of early skeletogenesis by Li, Yuk Yin, Lam, Kwok Lim, Chen, Abigail Dee, Zhang, Wei, Chan, Barbara Pui

“…Mesenchymal condensation is a critical transitional stage that precedes cartilage or bone formation. A microencapsulation technique was previously established…”
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Multiphoton microfabrication and micropatternining (MMM)-based screening of multiplex cell niche factors for phenotype maintenance - Bovine nucleus pulposus cell as an example by Yip, Chi Hung, Chen, Abigail Dee, Wong, Yu Hin, Chan, Barbara Pui

“…Upon monolayer cultures on flat and rigid plastic dishes, many cells de-differentiate and lose their native phenotype. Technologies able to identify and…”
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Mechanically induced formation and maturation of 3D-matrix adhesions (3DMAs) in human mesenchymal stem cells by Li, Chuen Wai, Lau, Yu Ting, Lam, Kwok Lim, Chan, Barbara Pui

“…Mechanical signal is important for regulating stem cell fate, but the molecular mechanisms involved are unclear. Cell-matrix adhesions are important molecular…”
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Injectable cell-encapsulating composite alginate-collagen platform with inducible termination switch for safer ocular drug delivery by Wong, Francisca Siu Yin, Tsang, Ken Kin, Chu, Amy Man Wah, Chan, Barbara Pui, Yao, Kwok Ming, Lo, Amy Cheuk Yin

“…Effective retinal drug delivery remains a challenge for treating vision-threatening diseases. Encapsulated-cell therapy (ECT) can provide local drug delivery…”
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