Search Results - "Chan, B P"

Maturation of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) in 3D collagen matrix: Effects of niche cell supplementation and mechanical stimulation by Zhang, W., Kong, C.W., Tong, M.H., Chooi, W.H., Huang, N., Li, R.A., Chan, B.P.

“…[Display omitted] Cardiomyocytes derived from human embryonic stem cells (hESC-CMs) are regarded as a promising source for regenerative medicine, drug testing…”
Get full text

Scaffolding in tissue engineering: general approaches and tissue-specific considerations by Chan, B. P., Leong, K. W.

“…Scaffolds represent important components for tissue engineering. However, researchers often encounter an enormous variety of choices when selecting scaffolds…”
Get full text

Fabrication of nano-fibrous collagen microspheres for protein delivery and effects of photochemical crosslinking on release kinetics by Chan, O.C.M., So, K.-F., Chan, B.P.

“…Protein compatibility is important for protein drug delivery using microsphere-based devices. Collagen has excellent protein compatibility but has poor…”
Get full text

Supplementation-time dependence of growth factors in promoting tendon healing by Chan, B P, Fu, S C, Qin, L, Rolf, C, Chan, K M

“…Growth factors potentially promote tendon healing. Understanding the right time to administer growth factors and the dosage of growth factors are prerequisites…”
Get more information

Compression-induced alignment and elongation of human mesenchymal stem cell (hMSC) in 3D collagen constructs is collagen concentration dependent by Kwok, C. B., Ho, F. C., Li, C. W., Ngan, A. H. W., Chan, D., Chan, B. P.

“…Controlling cell organization is important in tissue engineering. Guidance by aligned features on scaffolds or stimulation by physical signals can be used to…”
Get full text

Neuropsychiatric lupus and reversible posterior leucoencephalopathy syndrome: a challenging clinical dilemma by Mak, A., Chan, B. P. L., Yeh, I. B., Ho, R. C. M., Boey, M. L., Feng, P. H., Koh, D. R., Ong, B. K. C.

“…Reversible posterior leucoencephalopathy syndrome (RPLS) has been increasingly recognized and reported in the literature. While the condition has been well…”
Get full text

Photochemical crosslinking improves the physicochemical properties of collagen scaffolds by Chan, B. P., So, K.-F.

“…Collagen is a natural biomaterial with excellent biocompatibility. However, unprocessed collagen has low stability and weak mechanical strength, which limits…”
Get full text

Collagen microsphere based 3D culture system for human osteoarthritis chondrocytes (hOACs) by Yeung, P., Cheng, K. H., Yan, C. H., Chan, B. P.

“…The current study aims to evaluate collagen microencapsulation as an in vitro 3D culture platform for human osteoarthritic chondrocytes (hOACs), and to…”
Get full text

Assessment of intracranial collaterals on CT angiography in anterior circulation acute ischemic stroke by Yeo, L L L, Paliwal, P, Teoh, H L, Seet, R C, Chan, B P, Ting, E, Venketasubramanian, N, Leow, W K, Wakerley, B, Kusama, Y, Rathakrishnan, R, Sharma, V K

“…Intracranial collaterals influence the prognosis of patients treated with intravenous tissue plasminogen activator in acute anterior circulation ischemic…”
Get full text

Mesenchymal stem cell-collagen microspheres for articular cartilage repair: Cell density and differentiation status by Li, Y.Y., Cheng, H.W., Cheung, K.M.C., Chan, D., Chan, B.P.

“…Mesenchymal stem cells (MSC) hold promise for cartilage repair. A microencapsulation technique was previously established to entrap MSC in collagen…”
Get full text

A human osteoarthritis osteochondral organ culture model for cartilage tissue engineering by Yeung, P., Zhang, W., Wang, X.N., Yan, C.H., Chan, B.P.

“…In vitro human osteoarthritis (OA)-mimicking models enabling pathophysiological studies and evaluation of emerging therapies such as cartilage tissue…”
Get full text

Knocking out or pharmaceutical inhibition of fatty acid binding protein 4 (FABP4) alleviates osteoarthritis induced by high-fat diet in mice by Zhang, C., Chiu, K.Y., Chan, B.P.M., Li, T., Wen, C., Xu, A., Yan, C.H.

“…Adipokines play roles in the pathogenesis of osteoarthritis (OA). Fatty acid binding protein 4 (FABP4) is a novel adipokine that is closely associated with…”
Get full text

In vitro chondrogenic differentiation of human mesenchymal stem cells in collagen microspheres: Influence of cell seeding density and collagen concentration by Hui, T.Y, Cheung, K.M.C, Cheung, W.L, Chan, D, Chan, B.P

“…Abstract Given the inadequacies of existing repair strategies for cartilage injuries, tissue engineering approach using biomaterials and stem cells offers new…”
Get full text

Cell-derived matrices (CDM)-Methods, challenges and applications by Cheng, H W, Yuan, M T, Li, C W, Chan, B P

“…Extracellular matrix (ECM) provides both physical support and bioactive signals such as growth factors and cytokines to cells at their microenvironment or…”
Get full text

Iron supplement in pregnancy and development of gestational diabetes—a randomised placebo‐controlled trial by Chan, KKL, Chan, BCP, Lam, KF, Tam, S, Lao, TT

“…Objective  To test the hypothesis that iron supplement from early pregnancy would increase the risk of gestational diabetes mellitus (GDM). Design  Randomised…”
Get full text

Reconstitution of bone-like matrix in osteogenically differentiated mesenchymal stem cell–collagen constructs: A three-dimensional in vitro model to study hematopoietic stem cell niche by Lai, WY, Li, YY, Mak, SK, Ho, FC, Chow, ST, Chooi, WH, Chow, CH, Leung, AY, Chan, BP

“…Mesenchymal stem/stromal cells (MSCs) and osteoblasts are important niche cells for hematopoietic stem cells (HSCs) in bone marrow osteoblastic niche. Here, we…”
Get full text

Brain attack: needing resuscitation by Venketasubramanian, N, Chan, B P L, Chang, H M, Chua, H C, Gan, R N, Hui, F, Lee, W, Ng, I, Sharma, V K, Singh, R, Teoh, H L, Wang, E, Chen, C L H

“…The brain is extremely susceptible to focal ischaemia. Following vascular occlusion, a core of severely damaged brain tissue develops, surrounded by an…”
Get more information

Assessing current genetic status of the Hainan gibbon using historical and demographic baselines: implications for conservation management of species of extreme rarity by Bryant, J. V., Gottelli, D., Zeng, X., Hong, X., Chan, B. P. L., Fellowes, J. R., Zhang, Y., Luo, J., Durrant, C., Geissmann, T., Chatterjee, H. J., Turvey, S. T.

“…Evidence‐based conservation planning is crucial for informing management decisions for species of extreme rarity, but collection of robust data on genetic…”
Get full text

Effect of basic fibroblast growth factor. An in vitro study of tendon healing by Chan, B P, Chan, K M, Maffulli, N, Webb, S, Lee, K K

“…The effect of basic fibroblast growth factor on the proliferative and chemotactic response of cultured rat patellar tendon fibroblasts was studied in an in…”
Get more information

Drug carrier systems based on collagen–alginate composite structures for improving the performance of GDNF-secreting HEK293 cells by Lee, M, Lo, A.C, Cheung, P.T, Wong, D, Chan, B.P

“…Abstract Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor. Development of drug delivery technologies facilitating controlled…”
Get full text