Search Results - "Chan, Alex Siu Wing"
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Smad3 Promotes Cancer‐Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition
Published in Advanced science (01-01-2022)“…Cancer‐associated fibroblasts (CAFs) are important in tumor microenvironment (TME) driven cancer progression. However, CAFs are heterogeneous and still largely…”
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AANG: A natural compound formula for overcoming multidrug resistance via synergistic rebalancing the TGF‐β/Smad signalling in hepatocellular carcinoma
Published in Journal of cellular and molecular medicine (01-10-2021)“…Cancer cells are high in heterogeneity and versatility, which can easily adapt to the external stresses via both primary and secondary resistance. Targeting of…”
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Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage-Myofibroblast Transition in Non-Small-Cell Lung Carcinoma
Published in Advanced science (01-01-2024)“…Macrophage-myofibroblast transition (MMT) is a newly discovered pathway for mass production of pro-tumoral cancer-associated fibroblasts (CAFs) in non-small…”
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TGF-β Signaling: From Tissue Fibrosis to Tumor Microenvironment
Published in International journal of molecular sciences (15-07-2021)“…Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic…”
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TGF-β signaling networks in the tumor microenvironment
Published in Cancer letters (01-12-2022)“…Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology and pathology, especially in the progression of inflammatory diseases…”
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Health and Social Inclusion: The Impact of Psychological Well-Being and Suicide Attempts Among Older Men Who Have Sex With Men
Published in American journal of men's health (01-09-2022)“…Older adults’ mental health and suicidal tendencies have garnered much attention because of their vulnerability. Few studies have examined the impact of…”
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Letter to the Editor: Advocating Worldwide Social Inclusion and Anti-Discrimination Among LGBT Community
Published in Journal of homosexuality (16-04-2023)Get full text
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Tumour-associated macrophages: versatile players in the tumour microenvironment
Published in Frontiers in cell and developmental biology (26-10-2023)“…Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour microenvironment. Their roles in the cancer immunity are complicated, both…”
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Perceived Well-Being among Adults with Diabetes and Hypertension: A National Study
Published in Healthcare (Basel) (01-04-2024)“…Perceived health and distresses are associated with the practice of lifestyle modifications, which increases the risk of diabetes and hypertension-related…”
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Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy
Published in Exploration of targeted anti-tumor therapy (2023)“…Transforming growth factor-β (TGF-β) signaling is an important pathway for promoting the pathogenesis of inflammatory diseases, including cancer. The roles of…”
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Protocol to study immunodynamics in the tumor microenvironment using a tyramide signal amplification-based immunofluorescent multiplex panel
Published in STAR protocols (15-03-2024)“…Immunodynamics in the tumor microenvironment can be precisely examined by using multiple antigen identification approaches. Here, we present a protocol for…”
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Interprofessional Team-Based Learning: A Qualitative Study on the Experiences of Nursing and Physiotherapy Students
Published in Frontiers in public health (31-01-2022)“…Traditional discipline-specific training has limitations in facilitating inter-professional communication and collaboration. To address this issue, two local…”
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TGF-β1 Signaling: Immune Dynamics of Chronic Kidney Diseases
Published in Frontiers in medicine (25-02-2021)“…Chronic kidney disease (CKD) is a major cause of morbidity and mortality worldwide, imposing a great burden on the healthcare system. Regrettably, effective…”
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USMB-shMincle: a virus-free gene therapy for blocking M1/M2 polarization of tumor-associated macrophages
Published in Molecular therapy. Oncolytics (17-12-2021)“…Mincle is essential for tumor-associated macrophage (TAM)-driven cancer progression and represents a potential immunotherapeutic target for cancer…”
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RuPaul's Drag Race: A Cultural Phenomenon That Challenges Gender Norms and Sparks Conversations Across Borders
Published in Journal of homosexuality (02-07-2024)Get full text
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Promoting Social Equality and Psychological Well-Being: Addressing Discrimination Among Older Men Who Have Sex With Men
Published in American journal of men's health (01-07-2023)Get full text
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Exploring discrimination, social acceptance, and its impact on the psychological well-being of older men who have sex with men: A cross-sectional study
Published in BMC public health (02-01-2024)“…The exploration of discrimination, social acceptance, and their impact on the psychological well-being of older men who have sex with men (MSM) is a critical…”
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Application of Novel Psychoactive Substances: Chemsex and HIV/AIDS Policies Among Men Who Have Sex With Men in Hong Kong
Published in Frontiers in psychiatry (14-07-2021)Get full text
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Diversity and Inclusion: Impacts on Psychological Wellbeing Among Lesbian, Gay, Bisexual, Transgender, and Queer Communities
Published in Frontiers in psychology (29-04-2022)“…For scholars, practitioners, and legislators concerned about sexual minority adolescents, one of the main goals is to create more positive and inclusive…”
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