Search Results - "Chan, Adelyne S. L."

Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence by Olan, Ioana, Parry, Aled J., Schoenfelder, Stefan, Narita, Masako, Ito, Yoko, Chan, Adelyne S. L., Slater, Guy St.C., Bihary, Dóra, Bando, Masashige, Shirahige, Katsuhiko, Kimura, Hiroshi, Samarajiwa, Shamith A., Fraser, Peter, Narita, Masashi

“…Senescence is a state of stable proliferative arrest, generally accompanied by the senescence-associated secretory phenotype, which modulates tissue…”
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Locus-specific induction of gene expression from heterochromatin loci during cellular senescence by Tomimatsu, Kosuke, Bihary, Dóra, Olan, Ioana, Parry, Aled J, Schoenfelder, Stefan, Chan, Adelyne S L, Slater, Guy St C, Ito, Yoko, Rugg-Gunn, Peter J, Kirschner, Kristina, Bermejo-Rodriguez, Camino, Seko, Tomomi, Kugoh, Hiroyuki, Shiraishi, Ken, Sayama, Koji, Kimura, Hiroshi, Fraser, Peter, Narita, Masako, Samarajiwa, Shamith A, Narita, Masashi

“…Senescence is a fate-determined state, accompanied by reorganization of heterochromatin. Although lineage-appropriate genes can be temporarily repressed…”
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Tumour suppressors and cellular senescence by Chan, Adelyne S. L., Mowla, Sophia N., Arora, Parineeta, Jat, Parmjit S.

“…Cellular senescence is a stable cell cycle arrest that normal cells undergo in response to a variety of intrinsic and extrinsic stimuli, including progressive…”
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Titration of RAS alters senescent state and influences tumour initiation by Chan, Adelyne S. L., Zhu, Haoran, Narita, Masako, Cassidy, Liam D., Young, Andrew R. J., Bermejo-Rodriguez, Camino, Janowska, Aleksandra T., Chen, Hung-Chang, Gough, Sarah, Oshimori, Naoki, Zender, Lars, Aitken, Sarah J., Hoare, Matthew, Narita, Masashi

“…Oncogenic RAS-induced senescence (OIS) is an autonomous tumour suppressor mechanism associated with premalignancy 1 , 2 . Achieving this phenotype typically…”
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