Search Results - "Chamulitrat, Waleé"

Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors by Tiwari-Heckler, Shilpa, Gan-Schreier, Hongying, Stremmel, Wolfgang, Chamulitrat, Walee, Pathil, Anita

“…Non-alcoholic fatty liver disease (NAFLD) is associated with inefficient macro- and micronutrient metabolism, and alteration of circulating phospholipid…”
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iPLA2β-Null Mice Show HCC Protection by an Induction of Cell-Cycle Arrest after Diethylnitrosamine Treatment by Andrade, Adriana, Poth, Tanja, Brobeil, Alexander, Merle, Uta, Chamulitrat, Walee

“…Group VIA phospholipase A2 (iPLA2β) play diverse biological functions in epithelial cells and macrophages. Global deletion in iPLA2β-null (KO) mice leads to…”
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Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor by Carazo, Alejandro, Hyrsova, Lucie, Dusek, Jan, Chodounska, Hana, Horvatova, Alzbeta, Berka, Karel, Bazgier, Vaclav, Gan-Schreier, Hongying, Chamulitrat, Waleé, Kudova, Eva, Pavek, Petr

“…[Display omitted] •Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of PXR.•Acetylated DCA and CA enhance PXR target genes…”
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Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury by Ludwig, Johannes Maximilian, Zhang, Yuling, Chamulitrat, Walee, Stremmel, Wolfgang, Pathil, Anita

“…Endotoxin-mediated liver inflammation is a key component of many acute and chronic liver diseases contributing to liver damage, fibrosis and eventually organ…”
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Rescue of Hepatic Phospholipid Remodeling Defect in iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver by Chamulitrat, Walee, Jansakun, Chutima, Li, Huili, Liebisch, Gerhard

“…Polymorphisms of group VIA calcium-independent phospholipase A2 (iPLA2β or PLA2G6) are positively associated with adiposity, blood lipids, and Type-2 diabetes…”
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Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization by Su, Jie, Gan-Schreier, Hongying, Goeppert, Benjamin, Chamulitrat, Walee, Stremmel, Wolfgang, Pathil, Anita

“…Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) is a synthetic bile acid-phospholipid conjugate with profound hepatoprotective and anti-fibrogenic…”
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Role of gp91phox homolog nox1 in induction of premalignant spindle phenotypes of HPV 16 E6/E7-immortalized human keratinocytes by Chamulitrat, Walee

“…The NADPH oxidase (Nox) family of superoxide- and hydrogen peroxide-producing proteins has been recognized as important for signal transduction that regulates…”
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Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis by Seeßle, Jessica, Gan-Schreier, Hongying, Kirchner, Marietta, Stremmel, Wolfgang, Chamulitrat, Walee, Merle, Uta

“…Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption and therefore iron Overload. iron overload…”
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SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player by Zakrzewicz, Anna, Richter, Katrin, Zakrzewicz, Dariusz, Siebers, Kathrin, Damm, Jelena, Agné, Alisa, Hecker, Andreas, McIntosh, J Michael, Chamulitrat, Walee, Krasteva-Christ, Gabriela, Manzini, Ivan, Tikkanen, Ritva, Padberg, Winfried, Janciauskiene, Sabina, Grau, Veronika

“…Interleukin-1β (IL-1β) is a potent, pro-inflammatory cytokine of the innate immune system that plays an essential role in host defense against infection…”
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Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors by Siebers, Kathrin, Fink, Bijan, Zakrzewicz, Anna, Agné, Alisa, Richter, Katrin, Konzok, Sebastian, Hecker, Andreas, Zukunft, Sven, Küllmar, Mira, Klein, Jochen, McIntosh, J Michael, Timm, Thomas, Sewald, Katherina, Padberg, Winfried, Aggarwal, Nupur, Chamulitrat, Walee, Santoso, Sentot, Xia, Wendy, Janciauskiene, Sabina, Grau, Veronika

“…While interleukin (IL)-1β is a potent pro-inflammatory cytokine involved in host defense, high levels can cause life-threatening sterile inflammation including…”
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Adipocyte-specific Inactivation of Acyl-CoA Synthetase Fatty Acid Transport Protein 4 (Fatp4) in Mice Causes Adipose Hypertrophy and Alterations in Metabolism of Complex Lipids under High Fat Diet by Lenz, Lena-Solveig, Marx, Jana, Chamulitrat, Walee, Kaiser, Iris, Gröne, Hermann-Josef, Liebisch, Gerhard, Schmitz, Gerd, Elsing, Christoph, Straub, Beate K., Füllekrug, Joachim, Stremmel, Wolfgang, Herrmann, Thomas

“…Fatp4 exhibits acyl-CoA synthetase activity and is thereby able to catalyze the activation of fatty acids for further metabolism. However, its actual function…”
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iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation by Ming, Yanan, Zhu, Xingya, Tuma-Kellner, Sabine, Ganzha, Alexandra, Liebisch, Gerhard, Gan-Schreier, Hongying, Chamulitrat, Walee

“…: Group VIA calcium-independent phospholipase A2 (iPla2β) regulates homeostasis and remodeling of phospholipids (PL). We previously showed that iPla2β mice fed…”
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Study designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cells by Sattayakhom, Apsorn, Chunglok, Warangkana, Ittarat, Wanida, Chamulitrat, Walee

“…To investigate the role of NADPH oxidase homolog Nox1 at an early step of cell transformation, we utilized human gingival mucosal keratinocytes immortalized by…”
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Association of gp91phox homolog Nox1 with anchorage-independent growth and MAP kinase-activation of transformed human keratinocytes by CHAMULITRAT, Walee, SCHMIDT, Rainer, TOMAKIDI, Pascal, STREMMEL, Wolfgang, CHUNGLOK, Warangkana, KAWAHARA, Tsukasa, ROKUTAN, Kazuhito

“…Among five members of the NADPH oxidase (Nox) family, Nox1 confers mitogenic properties and is implicated to participate in the process of cell transformation…”
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Characterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolism by Armstrong, Jeffrey S, Rajasekaran, Mahadevan, Chamulitrat, Walee, Gatti, Paul, Hellstrom, Wayne.J, Sikka, Suresh C

“…Reactive oxygen species (ROS) inhibit sperm movement and have been implicated in male infertility. In this study, we determined the effects of specific ROS…”
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Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω-O-acylceramide by Yamamoto, Haruka, Hattori, Miku, Chamulitrat, Walee, Ohno, Yusuke, Kihara, Akio

“…The epidermis-specific lipid acylceramide plays a pivotal role in the formation of the permeability barrier in the skin; abrogation of its synthesis causes the…”
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FATP4 deletion in liver cells induces elevation of extracellular lipids via metabolic channeling towards triglycerides and lipolysis by Li, Huili, Seessle, Jessica, Staffer, Simone, Tuma-Kellner, Sabine, Poschet, Gernot, Herrmann, Thomas, Chamulitrat, Walee

“…Evidence from mice with global deletion of fatty-acid transport protein4 (FATP4) indicates its role on β-oxidation and triglycerides (TG) metabolism. We…”
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Role of fatty acid transport protein 4 in metabolic tissues: insights into obesity and fatty liver disease by Li, Huili, Herrmann, Thomas, Seeßle, Jessica, Liebisch, Gerhard, Merle, Uta, Stremmel, Wolfgang, Chamulitrat, Walee

“…Fatty acid (FA) metabolism is a series of processes that provide structural substances, signalling molecules and energy. Ample evidence has shown that FA…”
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Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease by Pathil, Anita, Mueller, Jan, Warth, Arne, Chamulitrat, Walee, Stremmel, Wolfgang

“…Hepatic fat accumulation and changes in lipid composition are hallmarks of nonalcoholic fatty liver disease (NAFLD). As an experimental approach for treatment…”
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Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation by Klement, Lukas, Jansakun, Chutima, Yan, Bin, Staffer, Simone, Tuma-Kellner, Sabine, Altamura, Sandro, Muckenthaler, Martina, Merle, Uta, Chamulitrat, Walee

“…Polymorphisms of group VIA calcium-independent phospholipase A2 (PLA2G6) are associated with blood C-reactive protein suggesting its role in inflammation. We…”
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