Search Results - "Champagne, Frances"

Early-life experience, epigenetics, and the developing brain by Kundakovic, Marija, Champagne, Frances A

“…Development is a dynamic process that involves interplay between genes and the environment. In mammals, the quality of the postnatal environment is shaped by…”
Get full text

Epigenetic mechanisms and the transgenerational effects of maternal care by Champagne, Frances A

“…Abstract The transmission of traits across generations has typically been attributed to the inheritance by offspring of genomic information from parental…”
Get full text

Epigenetic effects of prenatal stress on 11β-hydroxysteroid dehydrogenase-2 in the placenta and fetal brain by Jensen Peña, Catherine, Monk, Catherine, Champagne, Frances A

“…Maternal exposure to stress during pregnancy is associated with significant alterations in offspring neurodevelopment and elevated maternal glucocorticoids…”
Get full text

The neural mechanisms and consequences of paternal caregiving by Feldman, Ruth, Braun, Katharina, Champagne, Frances A.

“…In recent decades, human sociocultural changes have increased the numbers of fathers that are involved in direct caregiving in Western societies. This trend…”
Get full text

Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior by Monk, Catherine, Feng, Tianshu, Lee, Seonjoo, Krupska, Izabela, Champagne, Frances A., Tycko, Benjamin

“…Objective:Increased risk of psychopathology is observed in children exposed to maternal prenatal distress, and elevated maternal cortisol and epigenetic…”
Get full text

Environmental influence in the brain, human welfare and mental health by Tost, Heike, Champagne, Frances A, Meyer-Lindenberg, Andreas

“…Environmental influences affect the brain and mental health and often are social or have social components, even the more complex societal or area-level…”
Get full text

Beyond DNA: integrating inclusive inheritance into an extended theory of evolution by Danchin, Étienne, Charmantier, Anne, Champagne, Frances A, Mesoudi, Alex, Pujol, Benoit, Blanchet, Simon

“…Key Points An emerging idea in evolutionary biology is that inheritance implies more than the sole transmission of the DNA sequence across generations…”
Get full text

Epigenetic influence of social experiences across the lifespan by Champagne, Frances A.

“…The critical role of social interactions in driving phenotypic variation has long been inferred from the association between early social deprivation and…”
Get full text

Influence of maternal care on the developing brain: Mechanisms, temporal dynamics and sensitive periods by Curley, James P, Champagne, Frances A

“…Highlights • Variation in maternal care induces both short- and long-term neurobiological effects. • Maternal care predicts brain area-specific gene-specific…”
Get full text

Epigenetic perspective on the developmental effects of bisphenol A by Kundakovic, Marija, Champagne, Frances A

“…Abstract Bisphenol A (BPA) is an estrogenic environmental toxin widely used in the production of plastics and ubiquitous human exposure to this chemical has…”
Get full text

DNA methylation of BDNF as a biomarker of early-life adversity by Kundakovic, Marija, Gudsnuk, Kathryn, Herbstman, Julie B., Tang, Deliang, Perera, Frederica P., Champagne, Frances A.

“…Early-life adversity increases the risk for psychopathology in later life. The underlying mechanism(s) is unknown, but epigenetic variation represents a…”
Get full text

Epigenetic legacy of parental experiences: Dynamic and interactive pathways to inheritance by Champagne, Frances A

“…The quality of the environment experienced by an individual across his or her lifespan can result in a unique developmental trajectory with consequences for…”
Get more information

Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways by Monk, Catherine, Spicer, Julie, Champagne, Frances A

“…Prenatal exposure to maternal stress, anxiety, and depression can have lasting effects on infant development with risk of psychopathology. Although the impact…”
Get more information

Beyond the maternal epigenetic legacy by Champagne, Frances A.

“…In 2004, Weaver et al. published evidence in Nature Neuroscience for the lasting epigenetic impact of maternal care within the hippocampus of rat offspring…”
Get full text

Epigenetic mechanisms mediating the long-term effects of maternal care on development by Champagne, Frances A., Curley, James P.

“…The long-term consequences of early environmental experiences for development have been explored extensively in animal models to better understand the…”
Get full text

Early Environments, Glucocorticoid Receptors, and Behavioral Epigenetics by Champagne, Frances A

“…In 1985, a brief report published in Behavioral Neuroscience established the link between neonatal handling and concentrations of hippocampal glucocorticoid…”
Get full text

Interplay between paternal germline and maternal effects in shaping development: The overlooked importance of behavioural ecology by Champagne, Frances A., Joly, Dominque

“…Environmental conditions can have a lasting epigenetic impact on development, and there is increasing evidence that these effects can be transmitted across…”
Get full text

Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure by Kundakovic, Marija, Gudsnuk, Kathryn, Franks, Becca, Madrid, Jesus, Miller, Rachel L., Perera, Frederica P., Champagne, Frances A.

“…Bisphenol A (BPA) is an estrogenic endocrine disruptor widely used in the production of plastics. Increasing evidence indicates that in utero BPA exposure…”
Get full text

Epigenetics and the origins of paternal effects by Curley, James P., Mashoodh, Rahia, Champagne, Frances A.

“…Though there are multiple routes through which parents can influence their offspring, recent studies of environmentally induced epigenetic variation have…”
Get full text

Hormonal and non-hormonal bases of maternal behavior: The role of experience and epigenetic mechanisms by Stolzenberg, Danielle S., Champagne, Frances A.

“…This article is part of a Special Issue “Parental Care”. Though hormonal changes occurring throughout pregnancy and at the time of parturition have been…”
Get full text