Search Results - "Chamorro‐Arenas, Delfino"
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Transition‐Metal‐Free Multiple Functionalization of Piperidines to 4‐Substituted and 3,4‐Disubstituted 2‐Piperidinones
Published in Chemistry : a European journal (09-04-2020)“…Remote and multiple functionalization of piperidines without the use of transition‐metal catalysts and elaborate directing groups is one of the major…”
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Diastereoconvergent Synthesis of (–)‐Paroxetine
Published in European journal of organic chemistry (02-08-2017)“…A diastereoconvergent approach to (–)‐paroxetine from diastereomeric 3,4‐epoxy‐2‐piperidones is reported. For this synthesis, a regioselective and…”
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3
Stereoselective Synthesis and Antiallodynic Activity of 3‐Hydroxylated Paroxetines
Published in ChemMedChem (04-02-2021)“…The design, stereoselective synthesis and in vivo antiallodynic activity of four novel paroxetine analogs, named 3‐hydroxy paroxetines (3HPXs), is reported…”
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Selective, Catalytic, and Dual C(sp3)–H Oxidation of Piperazines and Morpholines under Transition-Metal-Free Conditions
Published in Journal of organic chemistry (21-12-2018)“…By using cheap and innocuous reagents, such as NaClO2, NaOCl, and catalytic amounts of TEMPO, a new environmentally friendly protocol for the selective and…”
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Frontispiece: Transition‐Metal‐Free Multiple Functionalization of Piperidines to 4‐Substituted and 3,4‐Disubstituted 2‐Piperidinones
Published in Chemistry : a European journal (09-04-2020)“…The C−H functionalization of unreactive sp3 carbon atoms under transition‐metal‐free conditions contribute, not only to the invention of novel methodologies…”
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6
Transition Metal-Free Selective Double sp3 C–H Oxidation of Cyclic Amines to 3‑Alkoxyamine Lactams
Published in Journal of organic chemistry (16-09-2016)“…The first chemical method for selective dual sp3 C–H functionalization at the alpha-and beta positions of cyclic amines to their corresponding 3-alkoxyamine…”
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7
Transition Metal-Free Selective Double sp(3) C-H Oxidation of Cyclic Amines to 3-Alkoxyamine Lactams
Published in Journal of organic chemistry (16-09-2016)“…The first chemical method for selective dual sp(3) C-H functionalization at the alpha-and beta positions of cyclic amines to their corresponding 3-alkoxyamine…”
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8
Antidepressant and Neuroprotective Effects of 3-Hydroxy Paroxetine, an Analog of Paroxetine in Rats
Published in The international journal of neuropsychopharmacology (22-03-2023)“…Abstract Background Paroxetine (PX) is a widely used antidepressant with side effects such as weakness, dizziness, and trouble sleeping. In search of novel…”
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9
Transition Metal-Free Selective Double sp 3 C–H Oxidation of Cyclic Amines to 3-Alkoxyamine Lactams
Published in Journal of organic chemistry (16-09-2016)Get full text
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