Search Results - "Chamoin, Sylvie"

Facile and Mild Synthesis of Linear and Cyclic Peptides via Thioesters by Agrigento, Paola, Albericio, Fernando, Chamoin, Sylvie, Dacquignies, Isabelle, Koc, Halil, Eberle, Martin

“…Thioester-mediated peptide bond formation has recently garnered a lot of attention, most notably in its relevance to condensation of large peptide fragments…”
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Automated Parallel Synthesis of N-Alkylated-?-Amino Methyl Esters in Gram Quantities by Sylvie Chamoin, Hans-Jörg Roth, Carsten Borek, Aline Jary, Hugues Maillot

“…N-alkylated-?-amino acids and methyl esters are a special class of building blocks used for the production of combinatorial libraries. They have two reactive…”
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The Stille cross coupling reactions on solid support. Link to solution phase directed ortho metalation. An ester linker approach to styryl, biaryl and heterobiaryl car☐ylic acids by Chamoin, Sylvie, Houldsworth, Stephen, Snieckus, Victor

“…The synthesis of the titled compounds by Stille cross coupling on Merrifield resin — linked halo benzoates with stannanes followed by LiOH hydrolysis is…”
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Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension by Shaw, Duncan E, Baig, Ferheen, Bruce, Ian, Chamoin, Sylvie, Collingwood, Stephen P, Cross, Sarah, Dayal, Satish, Drückes, Peter, Furet, Pascal, Furminger, Vikki, Haggart, Deborah, Hussey, Martin, Konstantinova, Irena, Loren, Jon C, Molteni, Valentina, Roberts, Sonia, Reilly, John, Saunders, Alex M, Stringer, Rowan, Sviridenko, Lilya, Thomas, Matthew, Thomson, Christopher G, Tomlins, Christine, Wen, Ben, Yeh, Vince, Pearce, Andrew C

“…A series of potent PDGFR inhibitors has been identified. The series was optimized for duration of action in the lung. A novel kinase occupancy assay was used…”
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Discovery of Potent and Selective Antibody–Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization by Karpov, Alexei S, Nieto-Oberhuber, Cristina M, Abrams, Tinya, Beng-Louka, Edwige, Blanco, Enrique, Chamoin, Sylvie, Chene, Patrick, Dacquignies, Isabelle, Daniel, Dylan, Dillon, Michael P, Doumampouom-Metoul, Lionel, Drosos, Nikolaos, Fedoseev, Pavel, Furegati, Markus, Granda, Brian, Grotzfeld, Robert M, Hess Clark, Suzanna, Joly, Emilie, Jones, Darryl, Lacaud-Baumlin, Marion, Lagasse-Guerro, Stephanie, Lorenzana, Edward G, Mallet, William, Martyniuk, Piotr, Marzinzik, Andreas L, Mesrouze, Yannick, Nocito, Sandro, Oei, Yoko, Perruccio, Francesca, Piizzi, Grazia, Richard, Etienne, Rudewicz, Patrick J, Schindler, Patrick, Velay, Mélanie, Venstrom, Kristine, Wang, Peiyin, Zurini, Mauro, Lafrance, Marc

“…Targeted antimitotic agents are a promising class of anticancer therapies. Herein, we describe the development of a potent and selective antimitotic Eg5…”
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Aryl-aryl Stille and Suzuki-Miyaura cross-coupling reactions on solid support by Chamoin, Sylvie Laurence Helene

“…The Stille and Suzuki-Miyaura cross coupling reactions in solution phase have proven to be effective methods for the formation of new carbon-carbon bonds. The…”
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Aryl -aryl Stille and Suzuki -Miyaura cross -coupling reactions on solid support by Chamoin, Sylvie Laurence Helene

“…The Stille and Suzuki-Miyaura cross coupling reactions in solution phase have proven to be effective methods for the formation of new carbon-carbon bonds. The…”
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