Search Results - "Chamkha, Imen"

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    Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose by Piel, Sarah, Chamkha, Imen, Dehlin, Adam Kozak, Ehinger, Johannes K, Sjövall, Fredrik, Elmér, Eskil, Hansson, Magnus J

    Published in PloS one (06-04-2020)
    “…Acetaminophen is one of the most common over-the-counter pain medications used worldwide and is considered safe at therapeutic dose. However, intentional and…”
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    Journal Article
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    Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity by Avram, Vlad F, Chamkha, Imen, Åsander-Frostner, Eleonor, Ehinger, Johannes K, Timar, Romulus Z, Hansson, Magnus J, Muntean, Danina M, Elmér, Eskil

    “…Statins are the cornerstone of lipid-lowering therapy. Although generally well tolerated, statin-associated muscle symptoms (SAMS) represent the main reason…”
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    Human papillomavirus-associated head and neck squamous cell carcinoma cells rely on glycolysis and display reduced oxidative phosphorylation by Li, Nora, Chamkha, Imen, Verma, Gaurav, Swoboda, Sabine, Lindstedt, Malin, Greiff, Lennart, Elmér, Eskil, Ehinger, Johannes

    Published in Frontiers in oncology (2023)
    “…Head and neck squamous cell carcinoma (HNSCC) constitutes a heterogeneous group of cancers. Human papilloma virus (HPV) is associated with a subtype of HNSCC…”
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    Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Amiodarone Toxicity by Bețiu, Alina M, Chamkha, Imen, Gustafsson, Ellen, Meijer, Elna, Avram, Vlad F, Åsander Frostner, Eleonor, Ehinger, Johannes K, Petrescu, Lucian, Muntean, Danina M, Elmér, Eskil

    “…Amiodarone is a potent antiarrhythmic drug and displays substantial liver toxicity in humans. It has previously been demonstrated that amiodarone and its…”
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    The relationship between mitochondrial respiration, resting metabolic rate and blood cell count in great tits by Thoral, Elisa, García-Díaz, Carmen C, Persson, Elin, Chamkha, Imen, Elmér, Eskil, Ruuskanen, Suvi, Nord, Andreas

    Published in Biology open (01-03-2024)
    “…Although mitochondrial respiration is believed to explain a substantial part of the variation in resting metabolic rate (RMR), few studies have empirically…”
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    Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production by Piel, Sarah, Ehinger, Johannes K., Chamkha, Imen, Frostner, Eleonor Åsander, Sjövall, Fredrik, Elmér, Eskil, Hansson, Magnus J.

    Published in Intensive care medicine experimental (01-08-2018)
    “…Background Metformin is the most common pharmacological treatment for type 2 diabetes. It is considered safe but has been associated with the development of…”
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    A whole blood approach improves speed and accuracy when measuring mitochondrial respiration in intact avian blood cells by Nord, Andreas, Chamkha, Imen, Elmér, Eskil

    Published in The FASEB journal (01-03-2023)
    “…Understanding mitochondrial biology and pathology is key to understanding the evolution of animal form and function. However, mitochondrial measurement often…”
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    Plasticity of mitochondrial function safeguards phosphorylating respiration during in vitro simulation of rest‐phase hypothermia by García‐Díaz, Carmen C., Chamkha, Imen, Elmér, Eskil, Nord, Andreas

    Published in The FASEB journal (01-04-2023)
    “…Many animals downregulate body temperature to save energy when resting (rest‐phase hypothermia). Small birds that winter at high latitudes have comparatively…”
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    Mitochondrial DNA triplication and punctual mutations in patients with mitochondrial neuromuscular disorders by Mkaouar-Rebai, Emna, Felhi, Rahma, Tabebi, Mouna, Alila-Fersi, Olfa, Chamkha, Imen, Maalej, Marwa, Ammar, Marwa, Kammoun, Fatma, Keskes, Leila, Hachicha, Mongia, Fakhfakh, Faiza

    “…Mitochondrial diseases are a heterogeneous group of disorders caused by the impairment of the mitochondrial oxidative phosphorylation system which have been…”
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    Do GSTM1 and GSTT1 polymorphisms influence the risk of developing mitochondrial diseases in a Tunisian population? by Ghorbel, Raouia, Ben Salah, Ghada, Ghorbel, Rania, Ben Mahmoud, Afif, Chamkha, Imen, Mkaouar-Rebai, Emna, Ammar-Keskes, Leila, Fakhfakh, Faiza

    “…Mitochondria play an essential role to supply the cell with metabolic energy in the form of adenosine triphosphate (ATP) through oxidative phosphorylation…”
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    A novel m.12908T>A mutation in the mitochondrial ND5 gene in patient with infantile-onset Pompe disease by Chamkha, Imen, Alila-Fersi, Olfa, Mkaouar-Rebai, Emna, Aloulou, Hajer, Kifagi, Chamseddine, Hachicha, Mongia, Fakhfakh, Faiza

    “…► A newborn boy with clinical features of Pompe disease was studied. ► A whole mitochondrial mutational analysis was performed. ► A novel mutation m.12908T>A…”
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    Molecular-Clinical Correlation in a Family With a Novel Heteroplasmic Leigh Syndrome Missense Mutation in the Mitochondrial Cytochrome c Oxidase III Gene by Mkaouar-Rebai, Emna, Ellouze, Emna, Chamkha, Imen, Kammoun, Fatma, Triki, Chahnez, Fakhfakh, Faiza

    Published in Journal of child neurology (01-01-2011)
    “…Cytochrome c oxidase is an essential component of the mitochondrial respiratory chain that catalyzes the reduction of molecular oxygen by reduced cytochrome c…”
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