Search Results - "Chambert, Kimberly"

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    Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia by Pocklington, Andrew J., Rees, Elliott, Walters, James T.R., Han, Jun, Kavanagh, David H., Chambert, Kimberly D., Holmans, Peter, Moran, Jennifer L., McCarroll, Steven A., Kirov, George, O’Donovan, Michael C., Owen, Michael J.

    Published in Neuron (Cambridge, Mass.) (03-06-2015)
    “…We sought to obtain novel insights into schizophrenia pathogenesis by exploiting the association between the disorder and chromosomal copy number (CNV) burden…”
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    Analysis of copy number variations at 15 schizophrenia-associated loci by REES, Elliott, WALTERS, James T. R, O'DONOVAN, Michael C, OWEN, Michael J, KIROV, George, GEORGIEVA, Lyudmila, ISLES, Anthony R, CHAMBERT, Kimberly D, RICHARDS, Alexander L, MAHONEY-DAVIES, Gerwyn, LEGGE, Sophie E, MORAN, Jennifer L, MCCARROLL, Steven A

    Published in British journal of psychiatry (01-02-2014)
    “…A number of copy number variants (CNVs) have been suggested as susceptibility factors for schizophrenia. For some of these the data remain equivocal, and the…”
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    Evidence of Common Genetic Overlap Between Schizophrenia and Cognition by Hubbard, Leon, Tansey, Katherine E, Rai, Dheeraj, Jones, Peter, Ripke, Stephan, Chambert, Kimberly D, Moran, Jennifer L, McCarroll, Steven A, Linden, David E J, Owen, Michael J, O'Donovan, Michael C, Walters, James T R, Zammit, Stanley

    Published in Schizophrenia bulletin (01-05-2016)
    “…Cognitive impairment is a core feature of schizophrenia but there is limited understanding of the genetic relationship between cognition in the general…”
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    De novo CNVs in bipolar affective disorder and schizophrenia by Georgieva, Lyudmila, Rees, Elliott, Moran, Jennifer L, Chambert, Kimberly D, Milanova, Vihra, Craddock, Nicholas, Purcell, Shaun, Sklar, Pamela, McCarroll, Steven, Holmans, Peter, O'Donovan, Michael C, Owen, Michael J, Kirov, George

    Published in Human molecular genetics (15-12-2014)
    “…An increased rate of de novo copy number variants (CNVs) has been found in schizophrenia (SZ), autism and developmental delay. An increased rate has also been…”
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    Using population admixture to help complete maps of the human genome by Genovese, Giulio, Handsaker, Robert E, Li, Heng, Altemose, Nicolas, Lindgren, Amelia M, Chambert, Kimberly, Pasaniuc, Bogdan, Price, Alkes L, Reich, David, Morton, Cynthia C, Pollak, Martin R, Wilson, James G, McCarroll, Steven A

    Published in Nature genetics (01-04-2013)
    “…Steven McCarroll, Giulio Genovese and colleagues report a new approach to help complete maps of the human genome reference sequence. They use a…”
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    LD Score regression distinguishes confounding from polygenicity in genome-wide association studies by Bulik-Sullivan, Brendan K, Loh, Po-Ru, Finucane, Hilary K, Ripke, Stephan, Yang, Jian, Patterson, Nick, Daly, Mark J, Price, Alkes L, Neale, Benjamin M

    Published in Nature genetics (01-03-2015)
    “…Benjamin Neale and colleagues report the LD Score regression method, used to distinguish the relative contributions of confounding bias and polygenicity to…”
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    Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia by Genovese, Giulio, Fromer, Menachem, Stahl, Eli A, Ruderfer, Douglas M, Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L, Purcell, Shaun M, Sklar, Pamela, Sullivan, Patrick F, Hultman, Christina M, McCarroll, Steven A

    Published in Nature neuroscience (01-11-2016)
    “…Using whole-exome sequencing, the authors identified 244,246 coding-sequence and splice-site ultra-rare variants (URVs) and found that gene-disruptive and…”
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    Differential Bile Acid Detection in Refractory GERD Patient Saliva Using a Simple and Sensitive Liquid Chromatography Tandem Mass Spectrometry Approach by Perez, Nisha, Chambert, Kimberly, Ribadeneira, Maria, Currie, Mark G., Chen, Yan, Kessler, Marco M.

    Published in Journal of clinical gastroenterology (01-03-2022)
    “…The aim was to measure bile acids in human saliva using a sensitive ultraperformance liquid chromatography tandem mass spectrometry analysis method to…”
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    Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia by Pardiñas, Antonio F, Smart, Sophie E, Willcocks, Isabella R, Holmans, Peter A, Dennison, Charlotte A, Lynham, Amy J, Legge, Sophie E, Baune, Bernhard T, Bigdeli, Tim B, Cairns, Murray J, Corvin, Aiden, Fanous, Ayman H, Frank, Josef, Kelly, Brian, McQuillin, Andrew, Melle, Ingrid, Mortensen, Preben B, Mowry, Bryan J, Pato, Carlos N, Periyasamy, Sathish, Rietschel, Marcella, Rujescu, Dan, Simonsen, Carmen, St Clair, David, Tooney, Paul, Wu, Jing Qin, Andreassen, Ole A, Kowalec, Kaarina, Sullivan, Patrick F, Murray, Robin M, Owen, Michael J, MacCabe, James H, O'Donovan, Michael C, Walters, James T R, Ajnakina, Olesya, Alameda, Luis, Barnes, Thomas R E, Berardi, Domenico, Bonora, Elena, Camporesi, Sara, Cleusix, Martine, Conus, Philippe, Crespo-Facorro, Benedicto, D'Andrea, Giuseppe, Demjaha, Arsime, Do, Kim Q, Doody, Gillian A, Eap, Chin B, Ferchiou, Aziz, Di Forti, Marta, Guidi, Lorenzo, Homman, Lina, Jenni, Raoul, Joyce, Eileen M, Kassoumeri, Laura, Khadimallah, Inès, Lastrina, Ornella, Muratori, Roberto, Noyan, Handan, O'Neill, Francis A, Pignon, Baptiste, Restellini, Romeo, Richard, Jean-Romain, Schürhoff, Franck, Španiel, Filip, Szöke, Andrei, Tarricone, Ilaria, Tortelli, Andrea, Üçok, Alp, Vázquez-Bourgon, Javier

    Published in JAMA psychiatry (Chicago, Ill.) (01-03-2022)
    “…About 20% to 30% of people with schizophrenia have psychotic symptoms that do not respond adequately to first-line antipsychotic treatment. This clinical…”
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