Search Results - "Chambers, Robert J"

Ultra Rate‐Dependent Pressure Sensitive Adhesives Enabled by Soft Elasticity of Liquid Crystal Elastomers by Annapooranan, Raja, Suresh Jeyakumar, Sunil, J. Chambers, Robert, Long, Rong, Cai, Shengqiang

“…The fabrication of pressure sensitive adhesives (PSAs) using liquid crystal elastomers (LCEs), which are known for their excellent dissipation properties, is…”
Get full text

Soft elasticity enabled adhesion enhancement of liquid crystal elastomers on rough surfaces by Annapooranan, Raja, Yeerella, Ram Hemanth, Chambers, Robert J, Li, Chenghai, Cai, Shengqiang

“…The fabrication of pressure-sensitive adhesives (PSA) using liquid crystal elastomers (LCE) that are tolerant to substrate roughness is explored in this work…”
Get full text

Gripping Aerial Topology Optimized Robot (GATOR) by Guibert, Alexandre T., Chambers, Robert J., Cao, Pengcheng, Kim, H. Alicia, Cai, Shengqiang, Kuester, Falko

“…This paper introduces the design, modeling, manufacturing, and testing of a Gripping Aerial Topology Optimized Robot (GATOR). The airframe of this unmanned…”
Get full text

Mechanically Robust and Biodegradable Electrospun Membranes Made from Bioderived Thermoplastic Polyurethane and Polylactic Acid by Chambers, Robert J., Rajput, Bhausaheb S., Scofield, Gordon B., Reindel, Jaysen, O’Shea, Katherine, Li, Richey Jiang, Simkovsky, Ryan, Mayfield, Stephen P., Burkart, Michael D., Cai, Shengqiang

“…Petroleum-based plastic waste plagues the natural environment, but plastics solve many high-performance solutions across industries. For example, porous…”
Get full text

Pharmacokinetics and Metabolism of a Cysteinyl Leukotriene-1 Receptor Antagonist from the Heterocyclic Chromanol Series in Rats: In Vitro-In Vivo Correlation, Gender-Related Differences, Isoform Identification, and Comparison with Metabolism in Human Hepatic Tissue by KUPERMAN, Alexander V, KALGUTKAR, Amit S, MARFAT, Anthony, CHAMBERS, Robert J, LISTON, Theodore E

“…CP-199,331 is a potent antagonist of the cysteinyl leukotriene-1 (LT 1 ) receptor, targeted for the treatment of asthma. The pharmacokinetic/metabolism…”
Get full text

A new chemical tool for exploring the physiological function of the PDE2 isozyme by Chambers, Robert J., Abrams, Kristin, Garceau, Norman Y., Kamath, Ajith V., Manley, Christopher M., Lilley, Susan C., Otte, Douglas A., Scott, Dennis O., Sheils, Alissa L., Tess, David A., Vellekoop, A. Samuel, Zhang, Yan, Lam, Kelvin T.

“…Oxindole ( 2) is a potent and selective PDE2 inhibitor with a favorable ADME, physiochemical and pharmacokinetic profile to allow for use as a chemical tool in…”
Get full text

Biarylcarboxylic Acids and -amides:  Inhibition of Phosphodiesterase Type IV versus [3H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret by Duplantier, Allen J, Biggers, Michael S, Chambers, Robert J, Cheng, John B, Cooper, Kelvin, Damon, David B, Eggler, James F, Kraus, Kenneth G, Marfat, Anthony, Masamune, Hiroko, Pillar, Joann S, Shirley, John T, Umland, John P, Watson, John W

“…In addition to having desirable inhibitory effects on inflammation, anaphylaxis, and smooth muscle contraction, PDE-IV inhibitors also produce undesirable side…”
Get full text

A new chemical tool for exploring the role of the PDE4D isozyme in leukocyte function by Chambers, Robert J., Abrams, Kristin, Castleberry, Tessa A., Cheng, John B., Fisher, Douglas A., Kamath, Ajith V., Marfat, Anthony, Nettleton, David O., Pillar, Joann D., Salter, Eben D., Sheils, Alissa L., Shirley, John T., Turner, Claudia R., Umland, John P., Lam, Kelvin T.

“…Nicotinamide ( 2) is a potent and selective inhibitor of the PDE4D isozyme and as a chemical tool selectively blocks eosinophil mediator release and chemotaxis…”
Get full text

Investigation of the Influence of Nanoscale Porosity in the Interfacial Layers on the Mechanical Properties of Helium Plasma-Exposed Tungsten by Cheng, Li, Patino, Marlene, Chambers, Robert J., Cai, Shengqiang, Baldwin, Matthew, Bandaru, Prabhakar

Get full text

Isoxazolyl, oxazolyl, and thiazolylpropionic acid derivatives as potent α4β1 integrin antagonists by DUPLANTIER, Allen J, BECKIUS, Gretchen E, WHITNEY, Carrie A, MILICI, Anthony J, CHAMBERS, Robert J, CHUPAK, Louis S, JENKINSON, Teresa H, KLEIN, Anne S, KRAUS, Kenneth G, KUDLACZ, Elizabeth M, MCKECHNEY, Michael W, PETTERSSON, Martin

Get full text

An Improved Synthesis of 5-Fluorothiophene-2-Carboxylic Acid by Chambers, Robert J., Marfat, Anthony

“…A new and efficient route to 5-fluorothiophene-2-carboxylic acid 1 was secured in two steps and 62% yield overall…”
Get full text

Correction to “Tailoring High Hardness and Rigidity in Biodegradable Thermoplastic Polyurethanes” by Jaisingh, Aanchal, Halloran, Matthew W., Rajput, Bhausaheb S., Chambers, Robert J., Reindel, Jaysen, O’Shea, Katherine A., Cai, Shengqiang, Burkart, Michael D.

Get full text

Dominance and Decomposition Heuristics for Single Machine Scheduling by Chambers, Robert J, Carraway, Robert L, Lowe, Timothy J, Morin, Thomas L

“…New heuristic dominance rules and a flexible decomposition heuristic are developed for the problem of minimizing weighted tardiness on a single processor…”
Get full text

Stereospecific synthesis of secondary allylic alcohols: selenoxide chemistry by Zoretic, Phillip A, Chambers, Robert J, Marbury, Gordon, Riebiro, Anthony A

Get full text

trans-3-benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor by REITER, L. A, KOCH, K, DIBRINO, J. N, DOMINY, B. W, FARRELL, C. A, HINGORANI, G. P, MARTINELLI, G. J, RAMCHANDANI, M, WRIGHT, K. F, PISCOPIO, A. D, SHOWELL, H. J, ALPERT, R, BIGGERS, M. S, CHAMBERS, R. J, CONKLYN, M. J, COOPER, K, CORTINA, S. R

Get full text

Isoxazolyl, oxazolyl, and thiazolylpropionic acid derivatives as potent α 4β 1 integrin antagonists by Duplantier, Allen J, Beckius, Gretchen E, Chambers, Robert J, Chupak, Louis S, Jenkinson, Teresa H, Klein, Anne S, Kraus, Kenneth G, Kudlacz, Elizabeth M, McKechney, Michael W, Pettersson, Martin, Whitney, Carrie A, Milici, Anthony J

“…A series of isoxazolyl, oxazolyl, and thiazolylpropionic acid derivatives derived from LDV was found to be a potent antagonist of the α 4β 1 integrin. The…”
Get full text

trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor by Reiter, L A, Koch, K, Piscopio, A D, Showell, H J, Alpert, R, Biggers, M S, Chambers, R J, Conklyn, M J, Cooper, K, Cortina, S R, Dibrino, J N, Dominy, B W, Farrell, C A, Hingorani, G P, Martinelli, G J, Ramchandani, M, Wright, K F

“…The SAR of a series of 2-(7-chromanyl)benzoic acids has been investigated with the aim of identifying potent and selective LTB4 receptor antagonists that…”
Get full text

trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B 4 (LTB 4) receptor by Reiter, Lawrence A., Koch, Kevin, Piscopio, Anthony D., Showell, Henry J., Alpert, Robbin, Biggers, Michael S., Chambers, Robert J., Conklyn, Maryrose J., Cooper, Kelvin, Cortina, Santo R., Dibrino, Joseph N., Dominy, Beryl W., Farrell, Cathy A., Hingorani, Gary P., Martinelli, Gary J., Ramchandani, Mukesh, Wright, Kathyrn F.

“…The SAR of a series of 2-(7-chromanyl)benzoic acids has been investigated with the aim of identifying potent and selective LTB 4 receptor antagonists that…”
Get full text

N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D 4 by Brown, Matthew F., Marfat, Anthony, Antognoli, Gerard, Chambers, Robert J., Cheng, John B., Damon, David B., Liston, Theodore E., McGlynn, Molly A., O'Sullivan, Stacie P., Owens, Brian S., Pillar, Joann S., Shirley, John T., Watson, John W.

“…Exploration of the indole nitrogen region of Zafirlukast ( 1) has uncovered a potent series of cysteinyl leukotriene D 4 (LTD 4) antagonists. These studies…”
Get full text

N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D4 by BROWN, M. F, MARFAT, A, PILLAR, J. S, SHIRLEY, J. T, WATSON, J. W, ANTOGNOLI, G, CHAMBERS, R. J, CHENG, J. B, DAMON, D. B, LISTON, T. E, MCGLYNN, M. A, O'SULLIVAN, S. P, OWENS, B. S

“…Exploration of the indole nitrogen region of Zafirlukast (1) has uncovered a potent series of cysteinyl leukotriene D4 (LTD4) antagonists. These studies showed…”
Get full text