Search Results - "Chambers, Jenny"

Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States During COVID-19 Pandemic by Garcia, Santiago, Albaghdadi, Mazen S., Meraj, Perwaiz M., Schmidt, Christian, Garberich, Ross, Jaffer, Farouc A., Dixon, Simon, Rade, Jeffrey J., Tannenbaum, Mark, Chambers, Jenny, Huang, Paul P., Henry, Timothy D.

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Porphyromonas gingivalis and Treponema denticola exhibit metabolic symbioses by Tan, Kheng H, Seers, Christine A, Dashper, Stuart G, Mitchell, Helen L, Pyke, James S, Meuric, Vincent, Slakeski, Nada, Cleal, Steven M, Chambers, Jenny L, McConville, Malcolm J, Reynolds, Eric C

“…Porphyromonas gingivalis and Treponema denticola are strongly associated with chronic periodontitis. These bacteria have been co-localized in subgingival…”
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Impact of COVID‐19 pandemic on STEMI care: An expanded analysis from the United States by Garcia, Santiago, Stanberry, Larissa, Schmidt, Christian, Sharkey, Scott, Megaly, Michael, Albaghdadi, Mazen S., Meraj, Perwaiz M., Garberich, Ross, Jaffer, Farouc A., Stefanescu Schmidt, Ada C., Dixon, Simon R., Rade, Jeffrey J., Smith, Timothy, Tannenbaum, Mark, Chambers, Jenny, Aguirre, Frank, Huang, Paul P., Kumbhani, Dharam J., Koshy, Thomas, Feldman, Dmitriy N., Giri, Jay, Kaul, Prashant, Thompson, Craig, Khalili, Houman, Maini, Brij, Nayak, Keshav R., Cohen, Mauricio G., Bangalore, Sripal, Shah, Binita, Henry, Timothy D.

“…Objective To evaluate the impact of COVID‐19 pandemic migitation measures on of ST‐elevation myocardial infarction (STEMI) care. Background We previously…”
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Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype by Abu‐Hayyeh, Shadi, Papacleovoulou, Georgia, Lövgren‐Sandblom, Anita, Tahir, Mehreen, Oduwole, Olayiwola, Jamaludin, Nurul Akmal, Ravat, Sabiha, Nikolova, Vanya, Chambers, Jenny, Selden, Clare, Rees, Myrddin, Marschall, Hanns‐Ulrich, Parker, Malcolm G., Williamson, Catherine

“…Intrahepatic cholestasis of pregnancy (ICP) is the most prevalent pregnancy‐specific liver disease and is associated with an increased risk of adverse fetal…”
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Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy by Geenes, Victoria, Chambers, Jenny, Khurana, Rshmi, Shemer, Elisabeth Wikstrom, Sia, Winnie, Mandair, Dalvinder, Elias, Elwyn, Marschall, Hanns-Ulrich, Hague, William, Williamson, Catherine

“…Abstract Objective To describe the use of combined ursodeoxycholic acid (UDCA) and rifampicin treatment in intrahepatic cholestasis of pregnancy (ICP). Study…”
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The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acid by Geenes, Victoria, Lövgren-Sandblom, Anita, Benthin, Lisbet, Lawrance, Dominic, Chambers, Jenny, Gurung, Vinita, Thornton, Jim, Chappell, Lucy, Khan, Erum, Dixon, Peter, Marschall, Hanns-Ulrich, Williamson, Catherine

“…Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disorder associated with an increased risk of adverse fetal outcomes. It is…”
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Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy by Kremer, Andreas E, Bolier, Ruth, Dixon, Peter H, Geenes, Victoria, Chambers, Jenny, Tolenaars, Dagmar, Ris-Stalpers, Carrie, Kaess, Bernhard M, Rust, Christian, van der Post, Joris A, Williamson, Catherine, Beuers, Ulrich, Oude Elferink, Ronald P.J

“…Background & Aims Intrahepatic cholestasis of pregnancy (ICP) is defined by pruritus, elevated total fasting serum bile salts (TBS) and transaminases, and an…”
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Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size by Papacleovoulou, Georgia, Nikolova, Vanya, Oduwole, Olayiwola, Chambers, Jenny, Vazquez‐Lopez, Marta, Jansen, Eugene, Nicolaides, Kypros, Parker, Malcolm, Williamson, Catherine

“…Maternal metabolic adaptations are essential for successful pregnancy outcomes. We investigated how metabolic gestational processes are coordinated, whether…”
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Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES) by Chappell, Lucy C, Chambers, Jenny, Dixon, Peter H, Dorling, Jon, Hunter, Rachael, Bell, Jennifer L, Bowler, Ursula, Hardy, Pollyanna, Juszczak, Edmund, Linsell, Louise, Rounding, Catherine, Smith, Anne, Williamson, Catherine, Thornton, Jim G

“…Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder specific to pregnancy and presents with maternal pruritus, raised concentrations…”
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Central carbon metabolism of Leishmania parasites by Saunders, Eleanor C, DE Souza, David P, Naderer, Thomas, Sernee, Marijke F, Ralton, Julie E, Doyle, Maria A, Macrae, James I, Chambers, Jenny L, Heng, Joanne, Nahid, Amsha, Likic, Vladimir A, McConville, Malcolm J

“…Leishmania spp. are sandfly-transmitted protozoa parasites that cause a spectrum of diseases in humans. Many enzymes involved in Leishmania central carbon…”
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Extensive Metabolic Remodeling Differentiates Non-pathogenic and Pathogenic Growth Forms of the Dimorphic Pathogen Talaromyces marneffei by Pasricha, Shivani, MacRae, James I, Chua, Hwa H, Chambers, Jenny, Boyce, Kylie J, McConville, Malcolm J, Andrianopoulos, Alex

“…Fungal infections are an increasing public health problem, particularly in immunocompromised individuals. While these pathogenic fungi show polyphyletic…”
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Ursodeoxycholic acid to reduce adverse perinatal outcomes for intrahepatic cholestasis of pregnancy: the PITCHES RCT by Chappell, Lucy C, Bell, Jennifer L, Smith, Anne, Rounding, Catherine, Bowler, Ursula, Linsell, Louise, Juszczak, Edmund, Tohill, Sue, Redford, Amanda, Dixon, Peter H, Chambers, Jenny, Hunter, Rachael, Dorling, Jon, Williamson, Catherine, Thornton, Jim G

“…Background Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and raised serum bile acid concentrations, is associated with increased…”
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Why research is so important by Chambers, Jenny

“…Jenny Chambers discusses the developments in research about intrahepatic cholestasis of pregnancy in recent years, that has taken place with the help of the…”
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Ask, ‘could it be ICP?’ by Chambers, Jenny

“…Intrahepatic cholestasis of pregnancy (ICP) is a condition that can have devastating consequences for women and babies. Jenny Chambers explains what ICP is and…”
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Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis by Gurung, Vinita, Williamson, Catherine, Chappell, Lucy, Chambers, Jenny, Briley, Annette, Broughton Pipkin, Fiona, Thornton, Jim

“…Obstetric cholestasis (OC) is a serious problem in pregnancy. It affects about 4500 women per year in the UK. Affected women develop itching and occasionally…”
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ELECTROCARDIOGRAM PATTERNS TO IDENTIFY LEFT MAIN DISEASE IN PATIENTS WITH ACUTE CORONARY SYNDROME by Bhandari, Amit, Murthy, Avinash M.A., Sharkey, Scott W., Henry, Timothy D., Garberich, Ross, Chambers, Jenny, Aguirre, Frank V.

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Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial by Chappell, Lucy C, Bell, Jennifer L, Smith, Anne, Linsell, Louise, Juszczak, Edmund, Dixon, Peter H, Chambers, Jenny, Hunter, Rachael, Dorling, Jon, Williamson, Catherine, Thornton, Jim G, Ahmed, Irshad, Arya, Rita, Beckett, Virginia, Bhide, Amarnath, Brown, Heather, Bugg, George, Cameron, Helen, Deole, Nishigandh, Dey, Madhuchanda, Dwyer, James, Fahel, Leila, Gada, Ruta, Girling, Joanna, Haestier, Anna, Hughes, Sean, Indusekhar, Radha, Jones, Bryony, Khan, Rahila, Kirkpatrick, Alison, Knox, Ellen, Lincoln, Karen, MacDougall, Malcolm, Majoko, Franz, McIntyre, Karen, Noori, Muna, Oakley, Wendy, Preston, Jane, Ranka, Poornima, Rashid, Mumtaz, Salloum, Marwan, Samyraju, Manjula, Schram, Catharina, Sen, Seema, Stone, Sophia, Tan, Bee

“…Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and increased serum bile acid concentrations, is associated with increased rates of…”
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Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses by Ovadia, Caroline, Seed, Paul T, Sklavounos, Alexandros, Geenes, Victoria, Di Ilio, Chiara, Chambers, Jenny, Kohari, Katherine, Bacq, Yannick, Bozkurt, Nuray, Brun-Furrer, Romana, Bull, Laura, Estiú, Maria C, Grymowicz, Monika, Gunaydin, Berrin, Hague, William M, Haslinger, Christian, Hu, Yayi, Kawakita, Tetsuya, Kebapcilar, Ayse G, Kebapcilar, Levent, Kondrackienė, Jūratė, Koster, Maria P H, Kowalska-Kańka, Aneta, Kupčinskas, Limas, Lee, Richard H, Locatelli, Anna, Macias, Rocio I R, Marschall, Hanns-Ulrich, Oudijk, Martijn A, Raz, Yael, Rimon, Eli, Shan, Dan, Shao, Yong, Tribe, Rachel, Tripodi, Valeria, Yayla Abide, Cigdem, Yenidede, Ilter, Thornton, Jim G, Chappell, Lucy C, Williamson, Catherine

“…Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers…”
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Whole-genome sequencing of a sporadic primary immunodeficiency cohort by Thaventhiran, James E. D., Lango Allen, Hana, Burren, Oliver S., Rae, William, Greene, Daniel, Staples, Emily, Zhang, Zinan, Farmery, James H. R., Simeoni, Ilenia, Rivers, Elizabeth, Maimaris, Jesmeen, Penkett, Christopher J., Stephens, Jonathan, Deevi, Sri V. V., Sanchis-Juan, Alba, Gleadall, Nicholas S., Thomas, Moira J., Sargur, Ravishankar B., Gordins, Pavels, Baxendale, Helen E., Brown, Matthew, Tuijnenburg, Paul, Worth, Austen, Hanson, Steven, Linger, Rachel J., Buckland, Matthew S., Rayner-Matthews, Paula J., Gilmour, Kimberly C., Samarghitean, Crina, Seneviratne, Suranjith L., Sansom, David M., Lynch, Andy G., Megy, Karyn, Ellinghaus, Eva, Ellinghaus, David, Jorgensen, Silje F., Karlsen, Tom H., Stirrups, Kathleen E., Cutler, Antony J., Kumararatne, Dinakantha S., Chandra, Anita, Edgar, J. David M., Herwadkar, Archana, Cooper, Nichola, Grigoriadou, Sofia, Huissoon, Aarnoud P., Goddard, Sarah, Jolles, Stephen, Schuetz, Catharina, Boschann, Felix, Lyons, Paul A., Hurles, Matthew E., Savic, Sinisa, Burns, Siobhan O., Kuijpers, Taco W., Turro, Ernest, Ouwehand, Willem H., Thrasher, Adrian J., Smith, Kenneth G. C.

“…Primary immunodeficiency (PID) is characterized by recurrent and often life-threatening infections, autoimmunity and cancer, and it poses major diagnostic and…”
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Does ursodeoxycholic acid improve perinatal outcomes in women with intrahepatic cholestasis of pregnancy? by Chappell, Lucy C, Chambers, Jenny, Thornton, Jim G, Williamson, Catherine

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