Search Results - "Chambers, Adam P"

The Role of Gut Adaptation in the Potent Effects of Multiple Bariatric Surgeries on Obesity and Diabetes by Seeley, Randy J., Chambers, Adam P., Sandoval, Darleen A.

“…Bariatric surgical procedures such as vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) are the most potent treatments available to produce…”
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The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice by Chambers, Adam P., Sorrell, Joyce E., Haller, April, Roelofs, Karen, Hutch, Chelsea R., Kim, Ki-Suk, Gutierrez-Aguilar, Ruth, Li, Bailing, Drucker, Daniel J., D’Alessio, David A., Seeley, Randy J., Sandoval, Darleen A.

“…Glucagon-like peptide 1 (GLP-1) is necessary for normal gluco-regulation, and it has been widely presumed that this function reflects the actions of GLP-1…”
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Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency by WILSON-PÉREZ, Hilary E, CHAMBERS, Adam P, RYAN, Karen K, BAILING LI, SANDOVAL, Darleen A, STOFFERS, Doris, DRUCKER, Daniel J, PÉREZ-TILVE, Diego, SEELEY, Randy J

“…Glucagon-like peptide 1 (GLP-1) is a peptide hormone that is released from the gut in response to nutrient ingestion and that has a range of metabolic effects,…”
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Integration of Satiety Signals by the Central Nervous System by Chambers, Adam P., Sandoval, Darleen A., Seeley, Randy J.

“…Individual meals are products of a complex interaction of signals related to both short-term and long-term availability of energy stores. In addition to…”
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Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight by Sisley, Stephanie R, Arble, Deanna M, Chambers, Adam P, Gutierrez-Aguilar, Ruth, He, Yanlin, Xu, Yong, Gardner, David, Moore, David D, Seeley, Randy J, Sandoval, Darleen A

“…Despite clear associations between vitamin D deficiency and obesity and/or type 2 diabetes, a causal relationship is not established. Vitamin D receptors…”
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The Effects of Vertical Sleeve Gastrectomy in Rodents Are Ghrelin Independent by Chambers, Adam P, Kirchner, Henriette, Wilson–Perez, Hilary E, Willency, Jill A, Hale, John E, Gaylinn, Bruce D, Thorner, Michael O, Pfluger, Paul T, Gutierrez, Jesus A, Tschöp, Matthias H, Sandoval, Darleen A, Seeley, Randy J

“…Reductions in levels of the hunger-stimulating hormone ghrelin have been proposed to mediate part of the effects of vertical sleeve gastrectomy (VSG) and…”
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Effect of vertical sleeve gastrectomy on food selection and satiation in rats by Chambers, Adam P, Wilson-Perez, Hilary E, McGrath, Sean, Grayson, Bernadette E, Ryan, Karen K, D'Alessio, David A, Woods, Stephen C, Sandoval, Darleen A, Seeley, Randy J

“…Vertical sleeve gastrectomy (VSG) is a restrictive procedure that reduces food intake to produce weight loss. Here we assess volume and nutrient effects on the…”
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All Bariatric Surgeries Are Not Created Equal: Insights from Mechanistic Comparisons by Stefater, Margaret A, Wilson-Pérez, Hilary E, Chambers, Adam P, Sandoval, Darleen A, Seeley, Randy J

“…Despite considerable scientific progress on the biological systems that regulate energy balance, we have made precious little headway in providing new…”
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Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy by Chambers, Adam P, Smith, Eric P, Begg, Denovan P, Grayson, Bernadette E, Sisley, Stephanie, Greer, Todd, Sorrell, Joyce, Lemmen, Lisa, LaSance, Kati, Woods, Stephen C, Seeley, Randy J, D'Alessio, David A, Sandoval, Darleen A

“…Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) are effective weight loss surgeries that also improve glucose metabolism. Rapid, early…”
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Modified Peptide YY Molecule Attenuates the Activity of NPY/AgRP Neurons and Reduces Food Intake in Male Mice by Jones, Edward S, Nunn, Nicolas, Chambers, Adam P, Østergaard, Søren, Wulff, Birgitte S, Luckman, Simon M

“…To study the effects of an analog of the gut-produced hormone peptide YY (PYY3-36), which has increased selectivity for the Y2 receptor; specifically, to…”
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Weight-Independent Changes in Blood Glucose Homeostasis After Gastric Bypass or Vertical Sleeve Gastrectomy in Rats by Chambers, Adam P, Jessen, Lene, Ryan, Karen K, Sisley, Stephanie, Wilson–Pérez, Hilary E, Stefater, Margaret A, Gaitonde, Shrawan G, Sorrell, Joyce E, Toure, Mouhamadoul, Berger, Jose, D'Alessio, David A, Woods, Stephen C, Seeley, Randy J, Sandoval, Darleen A

“…Background & Aims Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) reduce weight and improve glucose metabolism in obese patients,…”
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Sleeve Gastrectomy Induces Loss of Weight and Fat Mass in Obese Rats, but Does Not Affect Leptin Sensitivity by Stefater, Margaret A, Pérez–Tilve, Diego, Chambers, Adam P, Wilson–Pérez, Hilary E, Sandoval, Darleen A, Berger, José, Toure, Mouhamadoul, Tschöp, Matthias, Woods, Stephen C, Seeley, Randy J

“…Background & Aims Surgical intervention produces sustainable weight loss and metabolic improvement in obese individuals. Vertical sleeve gastrectomy (VSG)…”
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Roux-en-Y Gastric Bypass Surgery But Not Vertical Sleeve Gastrectomy Decreases Bone Mass in Male Rats by Stemmer, Kerstin, Bielohuby, Maximilian, Grayson, Bernadette E, Begg, Denovan P, Chambers, Adam P, Neff, Christina, Woods, Stephen C, Erben, Reinhold G, Tschöp, Matthias H, Bidlingmaier, Martin, Clemens, Thomas L, Seeley, Randy J

“…The most effective treatment for obesity is bariatric surgery. However, there is increasing concern that bariatric surgery can cause nutrient deficiencies that…”
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Sleeve Gastrectomy in Rats Improves Postprandial Lipid Clearance by Reducing Intestinal Triglyceride Secretion by Stefater, Margaret A, Sandoval, Darleen A, Chambers, Adam P, Wilson–Pérez, Hilary E, Hofmann, Susanna M, Jandacek, Ronald, Tso, Patrick, Woods, Stephen C, Seeley, Randy J

“…Background & Aims Postprandial hyperlipidemia is a risk factor for atherosclerotic heart disease and is associated with the consumption of high-fat diets and…”
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Cannabinoid 1 receptors are critical for the innate immune response to TLR4 stimulation by Duncan, Marnie, Galic, Michael A, Wang, Arthur, Chambers, Adam P, McCafferty, Donna-Marie, McKay, Derek M, Sharkey, Keith A, Pittman, Quentin J

“…Sickness behaviors are host defense adaptations that arise from integrated autonomic outputs in response to activation of the innate immune system. These…”
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Effect of guanylate cyclase-C activity on energy and glucose homeostasis by Begg, Denovan P, Steinbrecher, Kris A, Mul, Joram D, Chambers, Adam P, Kohli, Rohit, Haller, April, Cohen, Mitchell B, Woods, Stephen C, Seeley, Randy J

“…Uroguanylin is a gastrointestinal hormone primarily involved in fluid and electrolyte handling. It has recently been reported that prouroguanylin, secreted…”
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Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats by Chambers, Adam P, Stefater, Margaret A, Wilson-Perez, Hilary E, Jessen, Lene, Sisley, Stephanie, Ryan, Karen K, Gaitonde, Shrawan, Sorrell, Joyce E, Toure, Mouhamadoul, Berger, José, D'Alessio, David A, Sandoval, Darleen A, Seeley, Randy J, Woods, Stephen C

“…Abstract Bariatric surgery is the most efficacious procedure for eliciting weight loss in humans, and many patients undergoing the procedure experience…”
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The role of neuropeptide Y in energy homeostasis by Chambers, Adam P, Woods, Stephen C

“…When administered into the brain, NPY acts at Y1 and Y5 receptors to increase food intake. The response occurs with a short latency and is quite robust, such…”
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A neutral CB1 receptor antagonist reduces weight gain in rat by Chambers, Adam P, Vemuri, V Kiran, Peng, Yan, Wood, Jodianne T, Olszewska, Teresa, Pittman, Quentin J, Makriyannis, Alexandros, Sharkey, Keith A

“…Cannabinoid (CB)1 receptor inverse agonists inhibit food intake in animals and humans but also potentiate emesis. It is not clear whether these effects result…”
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The neutral cannabinoid CB1 receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat by Cluny, Nina L., Chambers, Adam P., Vemuri, V. Kiran, Wood, JodiAnne T., Eller, Lindsay K., Freni, Carmelina, Reimer, Raylene A., Makriyannis, Alexandros, Sharkey, Keith A.

“…The aim of this study was to determine if the neutral cannabinoid CB1 receptor antagonist, AM4113, regulates body weight in the rat via changes in food intake…”
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