Search Results - "Chamberland, Suzanne"
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Effective Treatment of Staphylococcus aureus Intramammary Infection in a Murine Model Using the Bacteriophage Cocktail StaphLyse
Published in Viruses (30-03-2023)“…causes intramammary infections (IMIs), which are refractory to antibiotic treatment and frequently result in chronic mastitis. IMIs are the leading cause of…”
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2
Bactericidal Activity of the Bacterial ATP Synthase Inhibitor Tomatidine and the Combination of Tomatidine and Aminoglycoside Against Persistent and Virulent Forms of Staphylococcus aureus
Published in Frontiers in microbiology (05-05-2020)“…Tomatidine (TO), a steroid alkaloid, exerts a strong bactericidal activity on the infection-persistent phenotype of , the small-colony variant (SCV), with a…”
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3
Staphylococcus aureus Small-Colony Variants from Airways of Adult Cystic Fibrosis Patients as Precursors of Adaptive Antibiotic-Resistant Mutations
Published in Antibiotics (Basel) (17-06-2023)“…Prototypic and their small-colony variants (SCVs) are predominant in cystic fibrosis (CF), but the interdependence of these phenotypes is poorly understood. We…”
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4
Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa: Novel Agents for Combination Therapy
Published in Antimicrobial Agents and Chemotherapy (01-01-2001)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5
Inhibitors of Efflux Pumps in Pseudomonas aeruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin
Published in Journal of medicinal chemistry (02-12-1999)Get full text
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Use of a Genetic Approach To Evaluate the Consequences of Inhibition of Efflux Pumps in Pseudomonas aeruginosa
Published in Antimicrobial Agents and Chemotherapy (01-06-1999)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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7
Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa
Published in Bioorganic & medicinal chemistry letters (11-03-2002)“…Several classes of peptidomimetics of the efflux pump inhibitor d-ornithine- d-homophenylalanine-3-aminoquinoline (MC-02,595) have been prepared and evaluated…”
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RWJ-54428 (MC-02,479), a New Cephalosporin with High Affinity for Penicillin-Binding Proteins, Including PBP 2a, and Stability to Staphylococcal Beta-Lactamases
Published in Antimicrobial Agents and Chemotherapy (01-02-2003)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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9
Secondary Staphylococcus aureus intramammary colonization is reduced by non-aureus staphylococci exoproducts
Published in Microbes and infection (01-02-2022)“…Non-aureus staphylococci (NAS) and Staphylococcus aureus are pathogens that cause bovine mastitis, a costly disease for dairy farmers, however; many NAS are…”
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10
Stereochemical Elucidation and Total Synthesis of Dihydropacidamycin D, a Semisynthetic Pacidamycin
Published in Journal of the American Chemical Society (07-02-2001)“…Hydrogenation of the C(4‘) exocyclic olefin of the pacidamycins has been shown to produce a series of semisynthetic compounds, the dihydropacidamycins, with…”
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11
In Vitro Activities of RWJ-54428 (MC-02,479) against Multiresistant Gram-Positive Bacteria
Published in Antimicrobial Agents and Chemotherapy (01-05-2001)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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12
From garden to lab: C-3 chemical modifications of tomatidine unveil broad-spectrum ATP synthase inhibitors to combat bacterial resistance
Published in European journal of medicinal chemistry (15-12-2023)“…Antibiotic resistance is escalating alarmingly worldwide. Bacterial resistance mechanisms are surfacing and proliferating across the globe, jeopardizing our…”
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13
Effective Treatment of IStaphylococcus aureus/I Intramammary Infection in a Murine Model Using the Bacteriophage Cocktail StaphLyse
Published in Viruses (01-03-2023)“…Staphylococcus aureus causes intramammary infections (IMIs), which are refractory to antibiotic treatment and frequently result in chronic mastitis. IMIs are…”
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14
IStaphylococcus aureus/I Small-Colony Variants from Airways of Adult Cystic Fibrosis Patients as Precursors of Adaptive Antibiotic-Resistant Mutations
Published in Antibiotics (Basel) (01-06-2023)“…Prototypic Staphylococcus aureus and their small-colony variants (SCVs) are predominant in cystic fibrosis (CF), but the interdependence of these phenotypes is…”
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15
Antibiotic Susceptibility Profiles of 941 Gram-Negative Bacteria Isolated from Septicemic Patients Throughout Canada
Published in Clinical infectious diseases (01-10-1992)“…The choice of antimicrobial therapy for the treatment of bacteremia is often empirical and based on the knowledge of antibiotic susceptibility profiles of the…”
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Azithromycin uptake and intracellular accumulation by Toxoplasma gondii-infected macrophages
Published in Journal of antimicrobial chemotherapy (01-09-1994)“…The uptake of azithromycin and erythromycin was measured in RAW 264.7 mouse macrophages infected with Toxoplasma gondii to determine whether the activity of…”
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17
Synthesis and antimicrobial evaluation of TAN-1057A/B analogs
Published in Journal of antibiotics (01-02-1998)“…TAN-1057A-D, dipeptides isolated from bacteria Flexibacter sp. PK-74 and PK-176, are new antibiotics with potent antibacterial activity against…”
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Discovery of RWJ-54428 (MC-02,479), a new cephalosporin active against resistant gram-positive bacteria
Published in Journal of antibiotics (2000)“…The discovery of RWJ-54428 (MC-02,479), a new cephalosporin displaying promising activity against sensitive and resistant Gram-positive bacteria, is described…”
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Discovery of MC-02,331, a new cephalosporin exhibiting potent activity against methicillin-resistant Staphylococcus aureus
Published in Journal of antibiotics (1998)“…A systematic approach toward building activity against methicillin-resistant staphylococci into the cephalosporin class of beta-lactam antibiotics is…”
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Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa
Published in Bioorganic & medicinal chemistry letters (18-08-2003)“…Conformational restriction of the ornithine residue of the efflux pump inhibitor d-ornithine- d-homophenylalanine-3-aminoquinoline (MC-02,595, 2) furnished…”
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