Search Results - "Chamberlain, M Dean"

Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis by Zhang, Boyang, Montgomery, Miles, Chamberlain, M. Dean, Ogawa, Shinichiro, Korolj, Anastasia, Pahnke, Aric, Wells, Laura A., Massé, Stéphane, Kim, Jihye, Reis, Lewis, Momen, Abdul, Nunes, Sara S., Wheeler, Aaron R., Nanthakumar, Kumaraswamy, Keller, Gordon, Sefton, Michael V., Radisic, Milica

“…We report the fabrication of a scaffold (hereafter referred to as AngioChip) that supports the assembly of parenchymal cells on a mechanically tunable matrix…”
Get full text

Digital microfluidic immunocytochemistry in single cells by Ng, Alphonsus H. C., Chamberlain, M. Dean, Situ, Haozhong, Lee, Victor, Wheeler, Aaron R.

“…We report a new technique called Digital microfluidic Immunocytochemistry in Single Cells (DISC). DISC automates protocols for cell culture, stimulation and…”
Get full text

Digital microfluidic isolation of single cells for -Omics by Lamanna, Julian, Scott, Erica Y., Edwards, Harrison S., Chamberlain, M. Dean, Dryden, Michael D. M., Peng, Jiaxi, Mair, Barbara, Lee, Adam, Chan, Calvin, Sklavounos, Alexandros A., Heffernan, Austin, Abbas, Farhana, Lam, Charis, Olson, Maxwell E., Moffat, Jason, Wheeler, Aaron R.

“…We introduce Digital microfluidic Isolation of Single Cells for -Omics (DISCO), a platform that allows users to select particular cells of interest from a…”
Get full text

The optoelectronic microrobot: A versatile toolbox for micromanipulation by Zhang, Shuailong, Scott, Erica Y., Singh, Jastaranpreet, Chen, Yujie, Zhang, Yanfeng, Elsayed, Mohamed, Chamberlain, M. Dean, Shakiba, Nika, Adams, Kelsey, Yu, Siyuan, Morshead, Cindi M., Zandstra, Peter W., Wheeler, Aaron R.

“…Microrobotics extends the reach of human-controlled machines to submillimeter dimensions. We introduce a microrobot that relies on optoelectronic tweezers…”
Get full text

Reconfigurable multi-component micromachines driven by optoelectronic tweezers by Zhang, Shuailong, Elsayed, Mohamed, Peng, Ran, Chen, Yujie, Zhang, Yanfeng, Peng, Jiaxi, Li, Weizhen, Chamberlain, M. Dean, Nikitina, Adele, Yu, Siyuan, Liu, Xinyu, Neale, Steven L., Wheeler, Aaron R.

“…There is great interest in the development of micromotors which can convert energy to motion in sub-millimeter dimensions. Micromachines take the micromotor…”
Get full text

Electrochemiluminescence on digital microfluidics for microRNA analysis by Shamsi, Mohtashim H., Choi, Kihwan, Ng, Alphonsus H.C., Chamberlain, M. Dean, Wheeler, Aaron R.

“…Electrochemiluminescence (ECL) is a sensitive analytical technique with great promise for biological applications, especially when combined with microfluidics…”
Get full text

Hepatic organoids for microfluidic drug screening by Au, Sam H, Chamberlain, M Dean, Mahesh, Shruthi, Sefton, Michael V, Wheeler, Aaron R

“…We introduce the microfluidic organoids for drug screening (MODS) platform, a digital microfluidic system that is capable of generating arrays of individually…”
Get more information

Towards a personalized approach to aromatase inhibitor therapy: a digital microfluidic platform for rapid analysis of estradiol in core-needle-biopsies by Abdulwahab, Sara, Ng, Alphonsus H C, Chamberlain, M Dean, Ahmado, Hend, Behan, Lucy-Ann, Gomaa, Hala, Casper, Robert F, Wheeler, Aaron R

“…Despite advances in breast cancer prevention and treatment, variability in patient-response has revealed the need for a more "personalized" approach to…”
Get more information

Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells by Zhang, Shuailong, Shakiba, Nika, Chen, Yujie, Zhang, Yanfeng, Tian, Pengfei, Singh, Jastaranpreet, Chamberlain, M. Dean, Satkauskas, Monika, Flood, Andrew G., Kherani, Nazir P., Yu, Siyuan, Zandstra, Peter W., Wheeler, Aaron R.

“…Optical micromanipulation has become popular for a wide range of applications. In this work, a new type of optical micromanipulation platform, patterned…”
Get full text

Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase by Chagpar, Ryaz B, Links, Philip H, Pastor, M. Chris, Furber, Levi A, Hawrysh, Andrea D, Chamberlain, M. Dean, Anderson, Deborah H

“…The phosphatidylinositol 3-kinase (PI3K) signaling pathway is deregulated in many human diseases including cancer, diabetes, obesity, and autoimmunity. PI3K…”
Get full text

Pre-concentration by liquid intake by paper (P-CLIP): a new technique for large volumes and digital microfluidics by Rackus, Darius G, de Campos, Richard P S, Chan, Calvin, Karcz, Maria M, Seale, Brendon, Narahari, Tanya, Dixon, Christopher, Chamberlain, M Dean, Wheeler, Aaron R

“…Microfluidic platforms are an attractive option for incorporating complex fluid handling into low-cost and rapid diagnostic tests. A persistent challenge for…”
Get more information

Cell invasion in digital microfluidic microgel systems by Li, Bingyu B, Scott, Erica Y, Chamberlain, M Dean, Duong, Bill T V, Zhang, Shuailong, Done, Susan J, Wheeler, Aaron R

“…Microfluidic methods for studying cell invasion can be subdivided into those in which cells invade into free space and those in which cells invade into…”
Get full text

Commentary on: “In Vivo Remodelling of Vascularizing Engineered Tissues” by Dean Chamberlain, M., West, Michael E. D., Lam, Gabrielle C., Sefton, Michael V.

Get full text

Disrupted RabGAP Function of the p85 Subunit of Phosphatidylinositol 3-Kinase Results in Cell Transformation by Chamberlain, M. Dean, Chan, Tim, Oberg, Jennifer C., Hawrysh, Andrea D., James, Kristy M., Saxena, Anurag, Xiang, Jim, Anderson, Deborah H.

“…Rab proteins regulate vesicle fusion events during the endocytosis, recycling, and degradation of activated receptor tyrosine kinases. The p85α subunit of…”
Get full text

A digital microfluidic method for multiplexed cell-based apoptosis assays by Bogojevic, Dario, Chamberlain, M Dean, Barbulovic-Nad, Irena, Wheeler, Aaron R

“…Digital microfluidics (DMF), a fluid-handling technique in which picolitre-microlitre droplets are manipulated electrostatically on an array of electrodes, has…”
Get more information

All-in-One digital microfluidics pipeline for proteomic sample preparation and analysis by Peng, Jiaxi, Chan, Calvin, Zhang, Shuailong, Sklavounos, Alexandros A, Olson, Maxwell E, Scott, Erica Y, Hu, Yechen, Rajesh, Vigneshwar, Li, Bingyu B, Chamberlain, M. Dean, Zhang, Shen, Peng, Hui, Wheeler, Aaron R

“…Highly sensitive and reproducible analysis of samples containing low amounts of protein is restricted by sample loss and the introduction of contaminants…”
Get full text

Digital Microfluidics for Immunoprecipitation by Seale, Brendon, Lam, Charis, Rackus, Darius G, Chamberlain, M. Dean, Liu, Chang, Wheeler, Aaron R

“…Immunoprecipitation (IP) is a common method for isolating a targeted protein from a complex sample such as blood, serum, or cell lysate. In particular, IP is…”
Get full text

Digital Microfluidic Cell Culture by Ng, Alphonsus H.C, Li, Bingyu Betty, Chamberlain, M. Dean, Wheeler, Aaron R

“…Digital microfluidics (DMF) is a droplet-based liquid-handling technology that has recently become popular for cell culture and analysis. In DMF, picoliter- to…”
Get full text

Escape from an Optoelectronic Tweezer Trap: experimental results and simulations by Zhang, Shuailong, Nikitina, Adele, Chen, Yujie, Zhang, Yanfeng, Liu, Lin, Flood, Andrew G, Juvert, Joan, Chamberlain, M Dean, Kherani, Nazir P, Neale, Steven L, Wheeler, Aaron R

“…Optoelectronic tweezers (OET) are a microsystem actuation technology capable of moving microparticles at mm s velocities with nN forces. In this work, we…”
Get full text

Fabrication of micro-tissues using modules of collagen gel containing cells by Chamberlain, M Dean, Butler, Mark J, Ciucurel, Ema C, Fitzpatrick, Lindsay E, Khan, Omar F, Leung, Brendan M, Lo, Chuen, Patel, Ritesh, Velchinskaya, Alexandra, Voice, Derek N, Sefton, Michael V

“…This protocol describes the fabrication of a type of micro-tissues called modules. The module approach generates uniform, scalable and vascularized tissues…”
Get full text