Search Results - "Chamberlain, Casey A."

Metabolomic profiling of oxalate-degrading probiotic Lactobacillus acidophilus and Lactobacillus gasseri by Chamberlain, Casey A, Hatch, Marguerite, Garrett, Timothy J

“…Oxalate, a ubiquitous compound in many plant-based foods, is absorbed through the intestine and precipitates with calcium in the kidneys to form stones. Over…”
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Metabolomic and lipidomic characterization of Oxalobacter formigenes strains HC1 and OxWR by UHPLC-HRMS by Chamberlain, Casey A., Hatch, Marguerite, Garrett, Timothy J.

“…Diseases of oxalate, such as nephrolithiasis and primary hyperoxaluria, affect a significant portion of the US population and have limited treatment options…”
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Impact of matrix effects and ionization efficiency in non-quantitative untargeted metabolomics by Chamberlain, Casey A., Rubio, Vanessa Y., Garrett, Timothy J.

“…Introduction LC–MS-based untargeted metabolomics has become increasingly popular due to the vast amount of information gained in a single analysis. Many…”
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The proteome of extracellular vesicles released by clastic cells differs based on their substrate by Rody, Jr, Wellington J, Chamberlain, Casey A, Emory-Carter, Alyssa K, McHugh, Kevin P, Wallet, Shannon M, Spicer, Victor, Krokhin, Oleg, Holliday, L Shannon

“…Extracellular vesicles (EVs) from osteoclasts are important regulators in intercellular communication. Here, we investigated the proteome of EVs from clastic…”
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A multidimensional metabolomics workflow to image biodistribution and evaluate pharmacodynamics in adult zebrafish by Jackstadt, Madelyn M, Chamberlain, Casey A, Doonan, Steven R, Shriver, Leah P, Patti, Gary J

“…An integrated evaluation of the tissue distribution and pharmacodynamic properties of a therapeutic is essential for successful translation to the clinic. To…”
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Extracellular Vesicle Analysis by Paper Spray Ionization Mass Spectrometry by Chamberlain, Casey A., Hatch, Marguerite, Garrett, Timothy J.

“…Paper spray ionization mass spectrometry (PSI-MS) is a direct MS analysis technique with several reported bacterial metabolomics applications. As with most…”
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Metabolomic Alteration in the Mouse Distal Colonic Mucosa after Oral Gavage with Oxalobacter formigenes by Chamberlain, Casey A., Hatch, Marguerite, Garrett, Timothy J.

“…Oxalobacter formigenes has been investigated for years due to its proposed ability to produce a secretagogue compound that initiates net intestinal oxalate…”
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Metabolomic and lipidomic characterization of an X-chromosome deletion disorder in neural progenitor cells by UHPLC-HRMS by Yazd, Hoda Safari, Rubio, Vanessa Y., Chamberlain, Casey A., Yost, Richard A., Garrett, Timothy J.

“…•LC-HRMS Metabolomics and lipidomics applied in X-chromosome deletion disorders.•Partial or complete deletion of the X chromosome is a very rare…”
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Strain-Level Differentiation of Bacteria by Paper Spray Ionization Mass Spectrometry by Chamberlain, Casey A, Rubio, Vanessa Y, Garrett, Timothy J

“…Paper spray ionization mass spectrometry (PSI-MS) is a relatively new analytical technique allowing for rapid mass spectrometric analysis of biological samples…”
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Oxalobacter formigenes produces metabolites and lipids undetectable in oxalotrophic Bifidobacterium animalis by Chamberlain, Casey A., Hatch, Marguerite, Garrett, Timothy J.

“…Introduction In the search for new potential therapies for pathologies of oxalate, such as kidney stone disease and primary hyperoxaluria, the intestinal…”
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195-LB: Metabolomic Characterization of Laron and Guevara-Rosenbloom Syndromes Using UHPLC-HRMS by RUBIO, VANESSA, CHAMBERLAIN, CASEY A., WASSERFALL, CLIVE, GUEVARA-AGUIRRE, JAIME, GUEVARA, ALEXANDRA, ROSENBLOOM, ARLAN L., ATKINSON, MARK A., YOST, RICHARD A., GARRETT, TIMOTHY J.

“…Laron syndrome (LS) is a rare autosomal recessive growth hormone (GH) insensitivity condition due to GH receptor mutation, and with phenotypic features likened…”
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Metabolomics by UHPLC-HRMS reveals the impact of heat stress on pathogen-elicited immunity in maize by Christensen, Shawn A., Santana, E’lysse A., Alborn, Hans T., Block, Anna K., Chamberlain, Casey A.

“…Introduction Studies investigating crop resistance to abiotic and biotic stress have largely focused on plant responses to singular forms of stress and…”
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Metabolomic and Lipidomic Characterization of Oxalobacter formigenes to Define Intestinal Oxalate Secretion by Chamberlain, Casey A, Hatch, Marguerite, Garrett, Timothy J

“…Kidney stone disease afflicts 1 in 11 people in the U.S. and burdens the economy with an annual treatment cost of over $10 billion. Nearly 80% of kidney stones…”
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Metabolomic Characterization of the Intestinal Bacterial Oxalobiome by Chamberlain, Casey A

“…The human intestinal microbiome is estimated to contain thousands of different species of bacteria, each which influences the health of the host in a unique…”
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