Search Results - "Chambaz, E."

Regulation of Protein Phosphatase 2A by Direct Interaction with Casein Kinase 2α by Hériché, Jean-Karim, Lebrin, Franck, Rabilloud, Thierry, Leroy, Didier, Chambaz, Edmond M., Goldberg, Yves

“…Timely deactivation of kinase cascades is crucial to the normal control of cell signaling and is partly accomplished by protein phosphatase 2A (PP2A). The…”
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Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization by Chantalat, Laurent, Leroy, Didier, Filhol, Odile, Nueda, Arsenio, Benitez, Maria Jose, Chambaz, Edmond M., Cochet, Claude, Dideberg, Otto

“…Protein kinase CK2 is a tetramer composed of two α catalytic subunits and two β regulatory subunits. The structure of a C‐terminal truncated form of the human…”
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Expression of the angiogenesis markers vascular endothelial growth factor-A, thrombospondin-1, and platelet-derived endothelial cell growth factor in human sporadic adrenocortical tumors : Correlation with genotypic alterations by DE FRAIPONT, F, EL ATIFI, M, GICQUEL, C, BERTAGNA, X, CHAMBAZ, E. M, FEIGE, J. J

“…Several studies have supported the hypothesis that adrenocortical tumor formation is the result of a multistep process. The angiogenic switch has been proposed…”
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Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: phosphorylation and activation by cAMP-dependent protein kinase by Rocchi, S, Gaillard, I, van Obberghen, E, Chambaz, E M, Vilgrain, I

“…During activation of adrenocortical cells by adrenocorticotrophic hormone (ACTH), tyrosine dephosphorylation of paxillin is stimulated and this correlates with…”
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Cushing's syndrome due to a gastric inhibitory polypeptide-dependent adrenal adenoma : Insights into hormonal control of adrenocortical tumorigenesis by CHABRE, O, LIAKOS, P, FEIGE, J.-J, VIVIER, J, CHAFFANJON, P, LABAT-MOLEUR, F, MARTINIE, M, BOTTARI, S. P, BACHELOT, I, CHAMBAZ, E. M, DEFAYE, G

“…We studied a patient with food-induced, ACTH-independent, Cushing's syndrome and a unilateral adrenocortical adenoma. In vivo cortisol secretion was stimulated…”
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Bovine adrenocortical cells in culture synthesize an ouabain-like compound by Perrin, A, Brasmes, B, Chambaz, E.M, Defaye, G

“…Ouabain or a closely related isomer, an `ouabain-like compound' (OLC), has been identified in plasma, by Hamlyn et al., using several physico-chemical and…”
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Demonstration of epidermal growth factor-induced receptor dimerization in living cells using a chemical covalent cross-linking agent by Cochet, C, Kashles, O, Chambaz, E M, Borrello, I, King, C R, Schlessinger, J

“…We have used the soluble covalent cross-linking agent 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDAC) to examine the capacity of epidermal growth factor…”
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Protein kinase CK2α is a target for the Abl and Bcr-Abl tyrosine kinases by HERICHE, J.-K, CHAMBAZ, E. M

“…Protein kinase CK2 is a ubiquitous serine-threonine kinase in which a catalytic alpha subunit often associates with a beta subunit. CK2 alpha is required for…”
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Casein kinase II and the tumor suppressor protein P53 associate in a molecular complex that is negatively regulated upon P53 phosphorylation by FILHOL, O, BAUDIER, J, DELPHIN, C, LOUE-MACKENBACH, P, CHAMBAZ, E. M, COCHET, C

“…Selective immunoisolation of P53 from Sf9 cells coexpressing wild-type P53 and casein kinase II yielded a preparation containing casein kinase II, thus…”
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F(ab) secondary antibodies: a general method for double immunolabeling with primary antisera from the same species. Efficiency control by chemiluminescence by Negoescu, A, Labat-Moleur, F, Lorimier, P, Lamarcq, L, Guillermet, C, Chambaz, E, Brambilla, E

“…We propose a general solution to the problem of using antibodies originating in the same species for double immunohistochemical labeling. It relies on the use…”
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DNA topoisomerase II and casein kinase II associate in a molecular complex that is catalytically active by Bojanowski, K, Filhol, O, Cochet, C, Chambaz, E.M., Larsen, A.K.

“…Immunoprecipitation of DNA topoisomerase II from yeast results in a preparation that contains casein kinase II; this suggests that the two proteins may…”
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A role for protein kinase CK2 in cell proliferation: evidence using a kinase-inactive mutant of CK2 catalytic subunit alpha by Lebrin, F, Chambaz, E M, Bianchini, L

“…Protein kinase CK2 is an ubiquitous and pleiotropic Ser/Thr protein kinase composed of two catalytic (alpha and/or alpha') and two regulatory (beta) subunits…”
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Cytoplasmic and nuclear distribution of casein kinase II: characterization of the enzyme uptake by bovine adrenocortical nuclear preparation by Filhol, O, Cochet, C, Chambaz, E. M

“…Casein kinase II (CK II) is a ubiquitous protein kinase that has been found in both nuclear and soluble subcellular fractions and whose precise cellular…”
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Long oligonucleotide arrays on nylon for large-scale gene expression analysis by El Atifi, M, Dupré, I, Rostaing, B, Chambaz, E M, Benabid, A L, Berger, F

“…To date, most studies of multigenic expression patterns by long DNA array have used DNA fragments as probes. These probes are usually obtained as PCR products,…”
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Hormonally regulated components of the adrenocortical cell environment and the control of adrenal cortex homeostasis by Feige, J J, Keramidas, M, Chambaz, E M

“…The extracellular matrix (ECM) strongly contributes to the regulation of cell proliferation and cell differentiation, and thereby of embryonic development and…”
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Organization of 3β-hydroxysteroid dehydrogenase/isomerase and cytochrome P450scc into a catalytically active molecular complex in bovine adrenocortical mitochondria by CHERRADI, N, CHAMBAZ, E. M, DEFAYE, G

“…We have previously reported the co-localization [Cherradi et al., Endocrinology 134 (1994) 1358-1364] of 3 beta-hydroxysteroid dehydrogenase/isomerase (3…”
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Smad3 Is Involved in the Intracellular Signaling Pathways That Mediate the Inhibitory Effects of Transforming Growth Factor-β on StAR Expression by Brand, C., Souchelnytskiy, S., Chambaz, E.M., Feige, J-J., Bailly, S.

“…Transforming growth factor βs (TGFβs) constitute a family of dimeric proteins that regulate growth and differentiation of many cell types. TGFβ1 is also a…”
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Coexpression of both .alpha. and .beta. subunits is required for assembly of regulated casein kinase II by Filhol, O, Cochet, C, Wedegaertner, P, Gill, G. N, Chambaz, E. M

“…Casein kinase II is an ubiquitous serine-threonine kinase whose functional significance and regulation in the living cell are not clearly understood. The…”
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Microarray RNA quantification assay for large-scale nanosamples analysis by Dupré, I, Atifi, M E, Rostaing, B, Chambaz, E M, Benabid, A L, Berger, F

“…We have developed a convenient and sensitive method for the quantification of RNA in samples from microbiopsies. This procedure is especially suitable for…”
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Binding of polyamines to an autonomous domain of the regulatory subunit of protein kinase CK2 induces a conformational change in the holoenzyme. A proposed role for the kinase stimulation by Leroy, D, Heriché, J K, Filhol, O, Chambaz, E M, Cochet, C

“…The means by which the cell regulates protein kinase CK2 remain obscure. However, natural polyamines, cellular compounds required for cell proliferation, have…”
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