Search Results - "Chamaillard, M"

A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation by Radulovic, K, Normand, S, Rehman, A, Delanoye-Crespin, A, Chatagnon, J, Delacre, M, Waldschmitt, N, Poulin, L F, Iovanna, J, Ryffel, B, Rosenstiel, P, Chamaillard, M

“…Flavones represent a class of polyphenols that are found in many plant-derived food sources. Herein, we provide evidence that the anti-inflammatory and…”
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PPARγ as a new therapeutic target in inflammatory bowel diseases by Dubuquoy, L, Rousseaux, C, Thuru, X, Peyrin-Biroulet, L, Romano, O, Chavatte, P, Chamaillard, M, Desreumaux, P

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Mesenteric fat in Crohn’s disease: a pathogenetic hallmark or an innocent bystander? by Peyrin-Biroulet, Laurent, Chamaillard, Mathias, Gonzalez, Florent, Beclin, Elodie, Decourcelle, Cecilia, Antunes, Laurent, Gay, Jérôme, Neut, Christel, Colombel, Jean-Frédéric, Desreumaux, Pierre

“…[...]other mediators such as angiotensinogen, plasminogen activator inhibitor-1 (PAI-1), visfatin, adisin and vaspin are produced by adipocytes. Local…”
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Gut microbiome and anticancer immune response: really hot Sht by Viaud, S, Daillère, R, Boneca, I G, Lepage, P, Langella, P, Chamaillard, M, Pittet, M J, Ghiringhelli, F, Trinchieri, G, Goldszmid, R, Zitvogel, L

“…The impact of gut microbiota in eliciting innate and adaptive immune responses beneficial for the host in the context of effective therapies against cancer has…”
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Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation by Couturier-Maillard, A, Froux, N, Piotet-Morin, J, Michaudel, C, Brault, L, Le Bérichel, J, Sénéchal, A, Robinet, P, Chenuet, P, Jejou, S, Dumoutier, L, Renauld, J C, Iovanna, J, Huber, S, Chamaillard, M, Quesniaux, VFJ, Sokol, H, Chamaillard, M, Ryffel, B

“…Upon oral infection with Toxoplasma gondii cysts (76 K strain) tachyzoites are released into the intestinal lumen and cross the epithelial barrier causing…”
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Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis by Dessein, R, Gironella, M, Vignal, C, Peyrin-Biroulet, L, Sokol, H, Secher, T, Lacas-Gervais, S, Gratadoux, J-J, Lafont, F, Dagorn, J-C, Ryffel, B, Akira, S, Langella, P, Nùñez, G, Sirard, J-C, Iovanna, J, Simonet, M, Chamaillard, M

“…Yersinia pseudotuberculosis causes ileitis and mesenteric lymphadenitis by mainly invading the Peyer's patches that are positioned in the terminal ileum…”
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Correction: Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation by Couturier-Maillard, A, Froux, N, Piotet-Morin, J, Michaudel, C, Brault, L, Le Bérichel, J, Sénéchal, A, Robinet, P, Chenuet, P, Jejou, S, Dumoutier, L, Renauld, J C, Iovanna, J, Huber, S, Chamaillard, M, Quesniaux, V F J, Sokol, H, Ryffel, B

“…The original version of this Article omitted the author Dr Mathias Chamaillard from the l’Institut de Pasteur, Lille, France. This has been corrected in both…”
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Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation by Philippe, D, Chakass, D, Thuru, X, Zerbib, P, Tsicopoulos, A, Geboes, K, Bulois, P, Breisse, M, Vorng, H, Gay, J, Colombel, J-F, Desreumaux, P, Chamaillard, M

“…Background and aims: Recent studies with μ opioid receptor (MOR) deficient mice support a physiological anti-inflammatory effect of MOR at the colon interface…”
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Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn’s disease colon by Berrebi, D, Maudinas, R, Hugot, J-P, Chamaillard, M, Chareyre, F, De Lagausie, P, Yang, C, Desreumaux, P, Giovannini, M, Cézard, J-P, Zouali, H, Emilie, D, Peuchmaur, M

“…Background: Crohn’s disease is one of the principal human chronic inflammatory bowel diseases. Although its aetiology is still unknown, its complex…”
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Microbial induction of CARD15 expression in intestinal epithelial cells via toll-like receptor 5 triggers an antibacterial response loop by Begue, B., Dumant, C., Bambou, J.C., Beaulieu, J.F., Chamaillard, M., Hugot, J.P., Goulet, O., Schmitz, J., Philpott, D.J., Cerf-Bensussan, N., Ruemmele, F.M.

“…With the discovery of CARD15 as susceptibility gene for Crohn's disease (CD) a first link to a potential defect in the innate immune system was made. In this…”
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P095 Neutralizing responsiveness to Interleukin-33 abrogat1es experimental colitis through enhanced mucosal wound healing by Sedhom, M.A., Pichery, M., Ortega, N., Foligné, B., Grandjean, T., Normand, S., Brault, L., Lefrancais, E., Fallon, P.G., Le Bert, M., Quesniaux, V., Chamaillard, M., Girard, J.-P., Bernhard, R.

“…Novel therapeutic principles are urgently needed to cure inflammatory bowel diseases (IBD) that have been intrinsically linked to a deregulated inflammatory…”
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Debugging the intestinal microbiota in IBD by Dessein, R., Rosenstiel, P., Chamaillard, M.

“…Besides its role in repelling enteropathogenic infections, the gastrointestinal tract is in intimate contact with commensal microbiota. Tremendous advances…”
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CARD4/NOD1 is not involved in inflammatory bowel disease by Zouali, H, Lesage, S, Merlin, F, Cézard, J-P, Colombel, J-F, Belaiche, J, Almer, S, Tysk, C, O’Morain, C, Gassull, M, Christensen, S, Finkel, Y, Modigliani, R, Gower-Rousseau, C, Macry, J, Chamaillard, M, Thomas, G, Hugot, J-P

“…Background and aims: Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are complex genetic disorders. CARD15/NOD2,…”
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Metronidazole: alternative treatment for ocular and cutaneous rosacea in the pediatric population by Léoni, S, Mesplié, N, Aitali, F, Chamaillard, M, Boralevi, F, Marques da Costa, C, Taïeb, A, Léauté-Labrèze, C, Colin, J, Mortemousque, B

“…To assess the effectiveness and tolerance of systemic metronidazole in the treatment of childhood ocular and cutaneous rosacea. Single-center multidisciplinary…”
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Early-onset sarcoidosis gets the nod by Chamaillard, Mathias, McDonald, Christine, Nuñez, Gabriel

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Treatment of moderate-to-severe psoriasis in adults: An expert consensus statement using a Delphi method to produce a decision-making algorithm by Poizeau, F., Leducq, S., Fardet, L., Beylot-Barry, M., Chaby, Guillaume, Chastagner, M., Corgibet, F., Gouillon, L., Jouan, N., Jullien, D., Acher, A., Amatore, F., Amici, J.-M., Aubert, H., Aubin, F., Beneton, N., Bouilly, D, Bursztejn, A.-C., Buzenet, C., Chamaillard-Pujol, M., Charles, J., Cottencin-Charriere, A.-C., Duval Modeste, B., Fauconneau, A., Fougerousse, A.-C., Girard, C., Goujon, C., Khemis, A., Le Ru, Y., Lepelley-Dupont, C., Mahé, E., Marcellin, X., Nicolas, C., Pallure, V., Parier, J., Quiles, N., Stoebner, P.-E., Tauber, M., Vermersch, A., Viguier, M., Villani, A.P., Chosidow, O., Guillot, B.

“…New highly effective drugs for moderate-to-severe cutaneous psoriasis are regularly marketed, and the hierarchy of treatments thus requires frequent review. A…”
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Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors by Pitt, Jonathan M., Vétizou, Marie, Daillère, Romain, Roberti, María Paula, Yamazaki, Takahiro, Routy, Bertrand, Lepage, Patricia, Boneca, Ivo Gomperts, Chamaillard, Mathias, Kroemer, Guido, Zitvogel, Laurence

“…Inhibition of immune regulatory checkpoints, such as CTLA-4 and the PD-1-PD-L1 axis, is at the forefront of immunotherapy for cancers of various histological…”
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[30] INVOLVEMENT OF NOD SIGNALLING IN HEPATOCYTE AND IMMUNE CELLS DURING HEPATITIS by Dubuquoy, L, Body-Malapel, M, Hugot, J.P, Giovannini, M, Chareyre, F, Gamier, E, Louvet, A, Chamaillard, M, Desreumaux, P, Dharancy, S, Mathurin, P

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Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility by Patsopoulos, Nikolaos A., Baranzini, Sergio E., Santaniello, Adam, Shoostari, Parisa, Cotsapas, Chris, Wong, Garrett, Beecham, Ashley H., James, Tojo, Replogle, Joseph, Vlachos, Ioannis S., McCabe, Cristin, Pers, Tune H., Brandes, Aaron, White, Charles, Keenan, Brendan, Cimpean, Maria, Winn, Phoebe, Panteliadis, Ioannis-Pavlos, Robbins, Allison, Andlauer, Till F. M., Zarzycki, Onigiusz, Dubois, Bénédicte, Goris, An, Søndergaard, Helle Bach, Sellebjerg, Finn, Sorensen, Per Soelberg, Ullum, Henrik, Thørner, Lise Wegner, Saarela, Janna, Cournu-Rebeix, Isabelle, Damotte, Vincent, Fontaine, Bertrand, Guillot-Noel, Lena, Lathrop, Mark, Vukusic, Sandra, Berthele, Achim, Pongratz, Viola, Buck, Dorothea, Gasperi, Christiane, Graetz, Christiane, Grummel, Verena, Hemmer, Bernhard, Hoshi, Muni, Knier, Benjamin, Korn, Thomas, Lill, Christina M., Luessi, Felix, Mühlau, Mark, Zipp, Frauke, Dardiotis, Efthimios, Agliardi, Cristina, Amoroso, Antonio, Barizzone, Nadia, Benedetti, Maria D., Bernardinelli, Luisa, Cavalla, Paola, Clarelli, Ferdinando, Comi, Giancarlo, Cusi, Daniele, Esposito, Federica, Ferrè, Laura, Galimberti, Daniela, Guaschino, Clara, Leone, Maurizio A., Martinelli, Vittorio, Moiola, Lucia, Salvetti, Marco, Sorosina, Melissa, Vecchio, Domizia, Zauli, Andrea, Santoro, Silvia, Mancini, Nicasio, Zuccalà, Miriam, Mescheriakova, Julia, van Duijn, Cornelia, Bos, Steffan D., Celius, Elisabeth G., Spurkland, Anne, Comabella, Manuel, Montalban, Xavier, Alfredsson, Lars, Bomfim, Izaura L., Gomez-Cabrero, David, Hillert, Jan, Jagodic, Maja, Lindén, Magdalena, Piehl, Fredrik, Jelčić, Ilijas, Martin, Roland, Sospedra, Mirela, Baker, Amie, Ban, Maria, Hawkins, Clive, Hysi, Pirro, Kalra, Seema, Karpe, Fredrik, Khadake, Jyoti, Lachance, Genevieve, Molyneux, Paul, Neville, Matthew

“…We analyzed genetic data of 47,429 multiple sclerosis (MS) and 68,374 control subjects and established a reference map of the genetic architecture of MS that…”
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Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects by Daillère, Romain, Vétizou, Marie, Waldschmitt, Nadine, Yamazaki, Takahiro, Isnard, Christophe, Poirier-Colame, Vichnou, Duong, Connie P.M., Flament, Caroline, Lepage, Patricia, Roberti, Maria Paula, Routy, Bertrand, Jacquelot, Nicolas, Apetoh, Lionel, Becharef, Sonia, Rusakiewicz, Sylvie, Langella, Philippe, Sokol, Harry, Kroemer, Guido, Enot, David, Roux, Antoine, Eggermont, Alexander, Tartour, Eric, Johannes, Ludger, Woerther, Paul-Louis, Chachaty, Elisabeth, Soria, Jean-Charles, Golden, Encouse, Formenti, Silvia, Plebanski, Magdalena, Madondo, Mutsa, Rosenstiel, Philip, Raoult, Didier, Cattoir, Vincent, Boneca, Ivo Gomperts, Chamaillard, Mathias, Zitvogel, Laurence

“…The efficacy of the anti-cancer immunomodulatory agent cyclophosphamide (CTX) relies on intestinal bacteria. How and which relevant bacterial species are…”
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