Search Results - "Challagulla, Arjun"

The swan genome and transcriptome, it is not all black and white by Karawita, Anjana C, Cheng, Yuanyuan, Chew, Keng Yih, Challagulla, Arjun, Kraus, Robert, Mueller, Ralf C, Tong, Marcus Z W, Hulme, Katina D, Bielefeldt-Ohmann, Helle, Steele, Lauren E, Wu, Melanie, Sng, Julian, Noye, Ellesandra, Bruxner, Timothy J, Au, Gough G, Lowther, Suzanne, Blommaert, Julie, Suh, Alexander, McCauley, Alexander J, Kaur, Parwinder, Dudchenko, Olga, Aiden, Erez, Fedrigo, Olivier, Formenti, Giulio, Mountcastle, Jacquelyn, Chow, William, Martin, Fergal J, Ogeh, Denye N, Thiaud-Nissen, Françoise, Howe, Kerstin, Tracey, Alan, Smith, Jacqueline, Kuo, Richard I, Renfree, Marilyn B, Kimura, Takashi, Sakoda, Yoshihiro, McDougall, Mathew, Spencer, Hamish G, Pyne, Michael, Tolf, Conny, Waldenström, Jonas, Jarvis, Erich D, Baker, Michelle L, Burt, David W, Short, Kirsty R

“…The Australian black swan (Cygnus atratus) is an iconic species with contrasting plumage to that of the closely related northern hemisphere white swans. The…”
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In Vitro Inhibition of Influenza Virus Using CRISPR/Cas13a in Chicken Cells by Challagulla, Arjun, Schat, Karel A, Doran, Timothy J

“…Advances in the field of CRISPR/Cas systems are expanding our ability to modulate cellular genomes and transcriptomes precisely and efficiently. Here, we…”
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Harnessing Intronic microRNA Structures to Improve Tolerance and Expression of shRNAs in Animal Cells by Challagulla, Arjun, Tizard, Mark L, Doran, Timothy J, Cahill, David M, Jenkins, Kristie A

“…Exogenous RNA polymerase III (pol III) promoters are commonly used to express short hairpin RNA (shRNA). Previous studies have indicated that expression of…”
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In Vivo Inhibition of Marek's Disease Virus in Transgenic Chickens Expressing Cas9 and gRNA against ICP4 by Challagulla, Arjun, Jenkins, Kristie A, O'Neil, Terri E, Shi, Shunning, Morris, Kirsten R, Wise, Terry G, Paradkar, Prasad N, Tizard, Mark L, Doran, Timothy J, Schat, Karel A

“…Marek's disease (MD), caused by MD herpesvirus (MDV), is an economically important disease in chickens. The efficacy of the existing vaccines against evolving…”
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Innovative approaches to genome editing in avian species by Cooper, Caitlin A, Doran, Timothy J, Challagulla, Arjun, Tizard, Mark L V, Jenkins, Kristie A

“…The tools available for genome engineering have significantly improved over the last 5 years, allowing scientist to make precise edits to the genome. Along…”
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Potential benefits of gene editing for the future of poultry farming by Tizard, Mark L., Jenkins, Kristie A., Cooper, Caitlin A., Woodcock, Mark E., Challagulla, Arjun, Doran, Timothy J.

“…The chicken is an exemplar of efficient intensive animal agriculture and provides two valuable food products, chicken meat and eggs. Only aquaculture is…”
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Germline engineering of the chicken genome using CRISPR/Cas9 by in vivo transfection of PGCs by Challagulla, Arjun, Jenkins, Kristie A., O'Neil, Terri E., Morris, Kirsten R., Wise, Terry G., Tizard, Mark L., Bean, Andrew G. D., Schat, Karel A., Doran, Timothy J.

“…Development of simple and readily adoptable methods to mediate germline engineering of the chicken genome will have many applications in research, agriculture…”
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Generation of gene edited birds in one generation using sperm transfection assisted gene editing (STAGE) by Cooper, Caitlin A., Challagulla, Arjun, Jenkins, Kristie A., Wise, Terry G., O’Neil, Terri E., Morris, Kirsten R., Tizard, Mark L., Doran, Timothy J.

“…Generating transgenic and gene edited mammals involves in vitro manipulation of oocytes or single cell embryos. Due to the comparative inaccessibility of avian…”
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Marker counter-selection via CRISPR/Cas9 co-targeting for efficient generation of genome edited avian cell lines and germ cells by Challagulla, Arjun, Shi, Shunning, Nair, Kiran, O'Neil, Terri E., Morris, Kirsten R., Wise, Terry G., Cahill, David M., Tizard, Mark L., Doran, Timothy J., Jenkins, Kristie A.

“…Efficient isolation of genetically modified cells that are phenotypically indistinguishable from the unmodified cells remains a major technical barrier for the…”
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Primary Chicken and Duck Endothelial Cells Display a Differential Response to Infection with Highly Pathogenic Avian Influenza Virus by Tong, Zhen Wei Marcus, Karawita, Anjana C., Kern, Colin, Zhou, Huaijun, Sinclair, Jane E., Yan, Limin, Chew, Keng Yih, Lowther, Sue, Trinidad, Lee, Challagulla, Arjun, Schat, Karel A., Baker, Michelle L., Short, Kirsty R.

“…Highly pathogenic avian influenza viruses (HPAIVs) in gallinaceous poultry are associated with viral infection of the endothelium, the induction of a ‘cytokine…”
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Inhibition of influenza virus in vivo by siRNA delivered using ABA triblock copolymer synthesized by reversible addition-fragmentation chain-transfer polymerization by Hinton, Tracey M, Challagulla, Arjun, Stewart, Cameron R, Guerrero-Sanchez, Carlos, Grusche, Felix A, Shi, Shuning, Bean, Andrew G, Monaghan, Paul, Gunatillake, Pathiraja A, Thang, San H, Tizard, Mark L

“…Influenza virus remains a major threat, with outbreaks continuing to occur. Few treatment options are available and drug resistance can emerge rapidly. New…”
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RAFT polymer delivered siRNA therapeutics to inhibit influenza virus replication by Thilak, Gunatillake, Tracey, Hinton, San, Thang, Shunning, Shi, Julian, Rosselgong, Carlos, Guerrero-Sanchez, Peter, Cass, Warren, Knower, Tam, Le, Megan, Dearnley, Paul, Monaghan, Mark, Tizard, Arjun, Challagulla, Camron, Stewart, Aa, Mohammed

“…Abstract only…”
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