Search Results - "Chakravarty, Shatadru"
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Tantalum oxide nanoparticles as versatile contrast agents for X-ray computed tomography
Published in Nanoscale (14-04-2020)“…Here, we describe the synthesis, characterization and in vitro and in vivo performance of a series of tantalum oxide (TaO ) based nanoparticles (NPs) for…”
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Discrete Nanomolecular Polyhedral Borane Scaffold Supporting Multiple Gadolinium(III) Complexes as a High Performance MRI Contrast Agent
Published in Inorganic chemistry (18-02-2013)“…An icosahedral closo-B12 2– scaffold supports 12 copies of Gd3+-chelate held in close proximity with each other by suitable linkers which employ azide–alkyne…”
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Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer
Published in Breast cancer research : BCR (28-11-2019)“…Prophylactic mastectomy is the most effective intervention to prevent breast cancer. However, this major surgery has life-changing consequences at the…”
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Abstract PS8-33: Image-guided intraductal ablation with refined ethanol solution for primary prevention of breast cancer
Published in Cancer research (Chicago, Ill.) (15-02-2021)“…Abstract Breast cancer (BC) is the most prevalent cancer and the second-leading cause of cancer-related death for women in the USA. For moderate-risk and,…”
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5
ANGI-12. MRI-BASED CELL TRACKING WITH INDIVIDUAL CELL SENSITIVITY FOR MEASURING CANCER CELL INVASION
Published in Neuro-oncology (Charlottesville, Va.) (05-11-2018)“…Abstract PURPOSE: GBM cell invasion is particularly aggressive and leads to poor prognosis. In vitro and in vivo cell tracking techniques for studying tumor…”
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Cobalt Telluride: A Highly Efficient Trifunctional Electrocatalyst for Water Splitting and Oxygen Reduction
Published in ACS applied energy materials (23-08-2021)“…Cobalt telluride has been identified as an efficient multifunctional electrocatalyst for oxygen and hydrogen evolution reactions and oxygen reduction reaction…”
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Abstract 26: Intraductal procedure with refined ethanol-containing ablative solution for primary prevention of breast cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Breast cancer (BC) is the second leading cause of cancer-related deaths in women. One in every eight women will develop BC during her lifetime. For…”
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Dynamic Contrast-Enhanced MRI of OATP Dysfunction in Diabetes
Published in Diabetes (New York, N.Y.) (01-02-2019)“…Diabetes is associated with hepatic metabolic dysfunction predisposing patients to drug-induced liver injury. Mouse models of type 2 diabetes (T2D) have…”
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X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models
Published in Journal of visualized experiments (09-12-2022)“…There are still a limited number of primary interventions for prevention of breast cancer. For women at a high risk of developing breast cancer, the most…”
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Fabrication of magnetic and fluorescent chitin and dibutyrylchitin sub-micron particles by oil-in-water emulsification
Published in Acta biomaterialia (01-11-2016)“…[Display omitted] Chitin is a carbohydrate polymer with unique pharmacological and immunological properties, however, because of its unwieldy chemistry, the…”
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Incorporating Tantalum Oxide Nanoparticles into Implantable Polymeric Biomedical Devices for Radiological Monitoring
Published in Advanced healthcare materials (01-07-2023)“…Longitudinal radiological monitoring of biomedical devices is increasingly important, driven by the risk of device failure following implantation. Polymeric…”
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Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models
Published in Journal of visualized experiments (01-04-2022)“…Breast cancer is the most prevalent cancer and the second-leading cause of cancer-related death for women in the USA. For high-risk women, prophylactic…”
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13
In vivo serial MRI of age-dependent neural progenitor cell migration in the rat brain
Published in NeuroImage (Orlando, Fla.) (01-10-2019)“…The subventricular zone (SVZ) is a neurogenic niche in the mammalian brain, giving rise to migratory neural progenitor cells (NPC). In rodents, it is…”
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Abstract 4247: Impact of 70% ethanol intraductal injections in MNU rat models for breast cancer prevention
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Breast cancer (BC) is the leading cancer diagnosis in women. While many BC treatment options exist, only two methods are approved for prevention…”
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Tantalum oxide nanoparticles as versatile and high-resolution X-ray contrast agent for intraductal image-guided ablative procedure in rodent models of breast cancer
Published in Npj imaging (2024)“…There are limited options for primary prevention of breast cancer (BC). Experimental procedures to locally prevent BC have shown therapeutic efficacy in animal…”
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Amphiphilic DTPA Multimer Assembled on Icosahedral Closo-Borane Motif as High-Performance MRI Blood Pool Contrast Agent
Published in ACS applied bio materials (20-09-2021)“…A multimeric MRI blood pool contrast agent based on the closo-borane motif is reported. Twelve copies of an amphiphilic DTPA chelate with amine end groups are…”
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Design Considerations to Facilitate Clinical Radiological Evaluation of Implantable Biomedical Structures
Published in ACS biomaterials science & engineering (08-02-2021)“…Clinical effectiveness of implantable medical devices would be improved with in situ monitoring to ensure device positioning, determine subsequent damage,…”
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Complex Relationship between Iron Oxide Nanoparticle Degradation and the Signal Intensity in Magnetic Particle Imaging
Published in ACS applied nano materials (22-05-2020)“…Magnetic particle imaging (MPI), using superparamagnetic nanoparticles as an imaging tracer, is touted as a quantitative biomedical imaging technology, but MPI…”
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Extensions of the Icosahedral Closomer Structure by Using Azide-Alkyne Click Reactions
Published in Angewandte Chemie International Edition (09-05-2011)“…Clusters with a click: The chemistry of icosahedral borane closomers has been combined with click chemistry for the first time. This approach provided a facile…”
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Extensions of the Icosahedral Closomer Structure by Using Azide-Alkyne Click Reactions
Published in Angewandte Chemie (09-05-2011)“…Cluster per Klick: Die Chemie der ikosaedrischen Boranclosomere wurde erstmals mit der Klickchemie kombiniert. Das Resultat war eine milde und effiziente…”
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