Search Results - "Chakradeo, Shweta"

Is Senescence Reversible? by Chakradeo, Shweta, Elmore, Lynne W, Gewirtz, David A

“…Senescence was originally identified by the finite lifespan of normal cells that is a consequence of telomere shortening with each cycle of DNA replication…”
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Autophagy inhibition for chemosensitization and radiosensitization in cancer: do the preclinical data support this therapeutic strategy? by Bristol, Molly L, Emery, Sean M, Maycotte, Paola, Thorburn, Andrew, Chakradeo, Shweta, Gewirtz, David A

“…Recognition of the cytoprotective functions of autophagy that occur in tumor cells exposed to various forms of chemotherapy or radiation has generated intense…”
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Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy by Chakradeo, Shweta, Sharma, Khushboo, Alhaddad, Aisha, Bakhshwin, Duaa, Le, Ngoc, Harada, Hisashi, Nakajima, Wataru, Yeudall, W Andrew, Torti, Suzy V, Torti, Frank M, Gewirtz, David A

“…The influence of autophagy inhibition on radiation sensitivity was studied in human breast, head and neck, and non-small cell lung cancer cell lines, in cell…”
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Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy by Chakradeo, Shweta, Sharma, Khushboo, Alhaddad, Aisha, Bakhshwin, Duaa, Le, Ngoc, Harada, Hisashi, Yeudall, W. Andrew, Torti, Suzy, Torti, Frank, Gewirtz, David

“…Abstract Our laboratory has previously described the four functional forms of autophagy, specifically cytoprotective, cytotoxic, cytostatic and nonprotective…”
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