Search Results - "Chakrabarti, Mrinmay"
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Synergistic anti-tumor actions of luteolin and silibinin prevented cell migration and invasion and induced apoptosis in glioblastoma SNB19 cells and glioblastoma stem cells
Published in Brain research (10-12-2015)“…Abstract Glioblastoma is the most lethal brain tumor. Failure of conventional chemotherapies prompted the search for natural compounds for treatment of…”
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Broad targeting of resistance to apoptosis in cancer
Published in Seminars in cancer biology (01-12-2015)“…Abstract Apoptosis or programmed cell death is natural way of removing aged cells from the body. Most of the anti-cancer therapies trigger apoptosis induction…”
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Effects of the isothiocyanate sulforaphane on TGF‐β1‐induced rat cardiac fibroblast activation and extracellular matrix interactions
Published in Journal of cellular physiology (01-08-2019)“…An important step in many pathological conditions, particularly tissue and organ fibrosis, is the conversion of relatively quiescent cells into active…”
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Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration
Published in Brain research bulletin (01-10-2014)“…Highlights • Estrogen receptor (ER) agonists play crucial roles in the immune system and the CNS. • Cell signaling pathways are modulated by ER agonists via…”
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miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo
Published in Experimental cell research (10-06-2013)“…Decrease in expression of the tumor suppressor microRNA-138 (miR-138) correlates well with an increase in telomerase activity in many human cancers. The…”
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miR-30e Blocks Autophagy and Acts Synergistically with Proanthocyanidin for Inhibition of AVEN and BIRC6 to Increase Apoptosis in Glioblastoma Stem Cells and Glioblastoma SNB19 Cells
Published in PloS one (07-07-2016)“…Glioblastoma is the most common and malignant brain tumor in humans. It is a heterogeneous tumor harboring glioblastoma stem cells (GSC) and other glioblastoma…”
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Photofrin based photodynamic therapy and miR-99a transfection inhibited FGFR3 and PI3K/Akt signaling mechanisms to control growth of human glioblastoma In vitro and in vivo
Published in PloS one (07-02-2013)“…Glioblastoma is the most common malignant brain tumor in humans. We explored the molecular mechanisms how the efficacy of photofrin based photodynamic therapy…”
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Alterations in expression of specific microRNAs by combination of 4-HPR and EGCG inhibited growth of human malignant neuroblastoma cells
Published in Brain research (15-05-2012)“…Abstract Malignant neuroblastomas are childhood tumors that remain mostly incurable. We explored efficacy of N-(4-hydroxyphenyl) retinamide (4-HPR) and…”
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Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells
Published in Neurochemical research (01-02-2013)“…Neuroblastoma is an extracranial solid tumor that usually occurs in infants and children. Malignant neuroblastomas remain mostly refractory to currently…”
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Molecular Signaling Mechanisms of Natural and Synthetic Retinoids for Inhibition of Pathogenesis in Alzheimer's Disease
Published in Journal of Alzheimer's disease (22-01-2016)“…Retinoids, which are vitamin A derivatives, interact through retinoic acid receptors (RARs) and retinoid X receptors (RXRs) and have profound effects on…”
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Combination of LC3 shRNA plasmid transfection and genistein treatment inhibited autophagy and increased apoptosis in malignant neuroblastoma in cell culture and animal models
Published in PloS one (18-10-2013)“…Malignant neuroblastoma is an extracranial solid tumor that usually occurs in children. Autophagy, which is a survival mechanism in many solid tumors including…”
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Hippo Signaling Mediates TGFβ-Dependent Transcriptional Inputs in Cardiac Cushion Mesenchymal Cells to Regulate Extracellular Matrix Remodeling
Published in Journal of cardiovascular development and disease (01-12-2023)“…The transforming growth factor beta (TGFβ) and Hippo signaling pathways are evolutionarily conserved pathways that play a critical role in cardiac fibroblasts…”
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KLF4 overexpression and apigenin treatment down regulated anti-apoptotic Bcl-2 proteins and matrix metalloproteinases to control growth of human malignant neuroblastoma SK-N-DZ and IMR-32 cells
Published in Molecular oncology (01-06-2013)“…Neuroblastoma is a childhood tumor that arises from immature neuroblasts of the sympathetic nervous system. Krüpple-like factor 4 (KLF4) is a transcription…”
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Increased TGFβ1 and SMAD3 Contribute to Age-Related Aortic Valve Calcification
Published in Frontiers in cardiovascular medicine (19-07-2022)“…Aims Calcific aortic valve disease (CAVD) is a progressive heart disease that is particularly prevalent in elderly patients. The current treatment of CAVD is…”
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Transforming Growth Factor Beta3 is Required for Cardiovascular Development
Published in Journal of cardiovascular development and disease (01-06-2020)“…Transforming growth factor beta3 ( ) gene mutations in patients of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD1) and Loeys-Dietz syndrome-5…”
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Molecular characterization of genome segments 1 and 3 encoding two capsid proteins of Antheraea mylitta cytoplasmic polyhedrosis virus
Published in Virology journal (04-08-2010)“…Antheraea mylitta cytoplasmic polyhedrosis virus (AmCPV), a cypovirus of Reoviridae family, infects Indian non-mulberry silkworm, Antheraea mylitta, and…”
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Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo
Published in Apoptosis (London) (01-03-2016)“…Glioblastoma is the deadliest brain tumor in humans. High systemic toxicity of conventional chemotherapies prompted the search for natural compounds for…”
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Molecular Cloning, Expression and Analysis of Antheraea mylitta Cypovirus Genome Segments 8 and 11
Published in International journal of virology (2010)“…The genome segments 8 (S8) and 11 (S11) of the 11 double-stranded segmented RNA genome of Antheraea mylitta cypovirus (AmCPV) were converted to cDNA, cloned…”
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Effects of emodin, a plant‐derived anthraquinone, on TGF‐β1‐induced cardiac fibroblast activation and function
Published in Journal of cellular physiology (01-11-2021)“…Cardiac fibrosis accompanies a number of pathological conditions and results in altered myocardial structure, biomechanical properties and function. The…”
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