Search Results - "Chain, BM"

Immunization with a Lentiviral Vector Stimulates both CD4 and CD8 T Cell Responses to an Ovalbumin Transgene by Rowe, Helen M, Lopes, Luciene, Ikeda, Yasuhiro, Bailey, Ranbir, Barde, Isabelle, Zenke, Martin, Chain, Benjamin M, Collins, Mary K

“…Lentiviral vectors encoding antigens are promising vaccine candidates because they transduce dendritic cells (DC) in vivo and prime CTL responses. Here we…”
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The Expression and Function of Cathepsin E in Dendritic Cells by Chain, Benjamin M, Free, Paul, Medd, Patrick, Swetman, Claire, Tabor, Alethea B, Terrazzini, Nadia

“…Cathepsin E is an aspartic proteinase that has been implicated in Ag processing within the class II MHC pathway. In this study, we document the presence of…”
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Is hepatitis C virus infection of dendritic cells a mechanism facilitating viral persistence? by Pachiadakis, Ioannis, Pollara, Gabriele, Chain, Benjamin M, Naoumov, Nikolai V

“…More than 170 million people worldwide are chronically infected with hepatitis C virus (HCV), which is a major cause of chronic hepatitis, cirrhosis, and…”
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Reactive oxygen species activate human peripheral blood dendritic cells by Rutault, Karine, Alderman, Charles, Chain, Benjamin M., Katz, David R.

“…This study investigates the effects of hydrogen peroxide, a potent oxygen free radical donor, on the phenotype and function of dendritic cells differentiated…”
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The role of advanced oxidation protein products in regulation of dendritic cell function by Alderman, Charles J.J, Shah, Sachit, Foreman, John C, Chain, Benjamin M, Katz, David R

“…The basis for this study was the “injury hypothesis,” which holds that release of micro-environmental constituents, such as reactive oxygen species and…”
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Variability and conservation in hepatitis B virus core protein by Chain, Benjamin M, Myers, Richard

“…Hepatitis B core protein (HBVc) has been extensively studied from both a structural and immunological point of view, but the evolutionary forces driving…”
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Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment? by ALDERMAN, Charles J. J, BUNYARD, Peter R, CHAIN, Benjamin M, FOREMAN, John C, LEAKE, David S, KATZ, David R

“…The objective of this study was to explore the relationship between low density lipoprotein (LDL) and dendritic cell (DC) activation, based upon the hypothesis…”
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JNK activation limits dendritic cell maturation in response to reactive oxygen species by the induction of apoptosis by Handley, Matthew E., Thakker, Manish, Pollara, Gabriele, Chain, Benjamin M., Katz, David R.

“…Dendritic cells (DC) sense infection in their local microenvironment and respond appropriately in order to induce T cell immunity. This response is mediated in…”
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Extension, retraction and contraction in the formation of a dendritic cell dendrite: distinct roles for Rho GTPases by Swetman, Claire A., Leverrier, Yann, Garg, Ritu, Gan, Chih H. V., Ridley, Anne J., Katz, David R., Chain, Benjamin M.

“…The morphology of antigen‐presenting dendritic cells (DC) is characterized by the possession of numerous long arborizing processes known as dendrites. The…”
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The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells by Tatla, Sangeeta, Woodhead, Vanessa, Foreman, John C, Chain, Benjamin M

“…This paper examines the hypothesis that reactive oxygen species (ROS) play an important role as second messengers in T cell activation. Activation of T cells…”
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LIGHTing up dendritic cell activation: Immune regulation and viral exploitation by Pollara, Gabriele, Katz, David R., Chain, Benjamin M.

“…The maturation state of dendritic cells (DC) is regulated by a variety of factors. These include ligands expressed by T cells, such as members of the TNF…”
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The host response to herpes simplex virus infection by Pollara, Gabriele, Katz, David R, Chain, Benjamin M

“…PURPOSE OF REVIEWInfection with herpes simplex virus remains a significant cause of disease. The host immune system plays an important role in containing viral…”
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Mannose-pepstatin conjugates as targeted inhibitors of antigen processing by Free, Paul, Hurley, Christopher A, Kageyama, Takashi, Chain, Benjamin M, Tabor, Alethea B

“…The molecular details of antigen processing, including the identity of the enzymes involved, their intracellular location and their substrate specificity, are…”
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Dendritic cells in viral pathogenesis: protective or defective? by Pollara, Gabriele, Kwan, Antonia, Newton, Philippa J., Handley, Matthew E., Chain, Benjamin M., Katz, David R.

“…Summary Dendritic cells (DC) are potent antigen‐presenting cells that are critical in the initiation of immune responses to control and/or eliminate viral…”
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Structural Relationships and Cellular Tropism of Staphylococcal Superantigen-Like Proteins by AL-SHANGITI, Ali M, NAYLOR, Claire E, NAIR, Sean P, BRIGGS, David C, HENDERSON, Brian, CHAIN, Benjamin M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Regulation of CD43-induced U937 homotypic aggregation by Cho, Jae Youl, Chain, Benjamin M, Vives, Jordi, Horejsi, Vaclav, Katz, David R

“…CD43 (leukosialin, sialophorin), a prominent component of the hemopoietic cell surface, has an enigmatic role in cell–cell interaction. The observation that…”
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CD98-dependent homotypic aggregation is associated with translocation of protein kinase cδ and activation of mitogen-activated protein kinases by Cho, Jae Youl, Skubitz, Keith M, Katz, David R, Chain, Benjamin M

“…CD98 is a protein found on the surface of many activated cell types, and is implicated in the regulation of cellular differentiation, adhesion, growth, and…”
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Cynaropicrin, a sesquiterpene lactone, as a new strong regulator of CD29 and CD98 functions by Cho, Jae Youl, Kim, Ae Ra, Joo, Hong-Gu, Kim, Byung-hun, Rhee, Man Hee, Yoo, Eun Sook, Katz, David R, Chain, Benjamin M, Jung, Jee H

“…Cynaropicrin is a sesquiterpene lactone displaying immunomodulatory effects on the production of cytokine and nitric oxide from macrophages/monocytes. In this…”
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A defect in bone marrow derived dendritic cell maturation in the nonobesediabetic mouse by Strid, J., Lopes, L., Marcinkiewicz, J., Petrovska, L., Nowak, B., Chain, B. M., Lund, T.

“…The pathogenesis of diabetes in the nonobese diabetic (NOD) mouse is characterized by a selective destruction of the insulin‐producing β‐cells in the islets of…”
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Placentally derived prostaglandin E(2) acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells by Kvirkvelia, N, Vojnovic, I, Warner, T D, Athie-Morales, V

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