Search Results - "Chaigneau, L."

Advanced chondrosarcomas: role of chemotherapy and survival by Italiano, A., Mir, O., Cioffi, A., Palmerini, E., Piperno-Neumann, S., Perrin, C., Chaigneau, L., Penel, N., Duffaud, F., Kurtz, J.E., Collard, O., Bertucci, F., Bompas, E., Le Cesne, A., Maki, R.G., Ray Coquard, I., Blay, J.Y.

“…There are limited data about the role of chemotherapy in patients with advanced chondrosarcomas. The medical charts of 180 patients with advanced…”
Get full text

Systemic high-dose intravenous methotrexate in patients with central nervous system metastatic breast cancer by Bazan, F, Dobi, E, Royer, B, Curtit, E, Mansi, L, Menneveau, N, Paillard, M J, Meynard, G, Villanueva, C, Pivot, X, Chaigneau, L

“…Infusion of high-dose intravenous methotrexate (MTX) has been demonstrating to penetrate the blood-brain barrier. The aim of this present study was to assess…”
Get full text

Metastatic angiosarcomas: doxorubicin-based regimens, weekly paclitaxel and metastasectomy significantly improve the outcome by Penel, N., Italiano, A., Ray-Coquard, I., Chaigneau, L., Delcambre, C., Robin, Y.M., Bui, B., Bertucci, F., Isambert, N., Cupissol, D., Bompas, E., Bay, J.O., Duffaud, F., Guillemet, C., Blay, J.Y.

“…Angiosarcomas are a rare but aggressive form of soft tissue sarcoma. At metastatic stage, the clinical benefit of therapeutic intervention remains debatable…”
Get full text

A randomized phase III trial comparing trabectedin to best supportive care in patients with pre-treated soft tissue sarcoma: T-SAR, a French Sarcoma Group trial by Le Cesne, A., Blay, J.-Y., Cupissol, D., Italiano, A., Delcambre, C., Penel, N., Isambert, N., Chevreau, C., Bompas, E., Bertucci, F., Chaigneau, L., Piperno-Neumann, S., Salas, S., Rios, M., Guillemet, C., Bay, J.-O., Ray-Coquard, I., Haddag, L., Bonastre, J., Kapso, R., Fraslin, A., Bouvet, N., Mir, O., Foulon, S.

“…The French Sarcoma Group assessed the efficacy, safety, and quality of life (QoL) of trabectedin versus best supportive care (BSC) in patients with advanced…”
Get full text

Masitinib in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib: A randomized controlled open-label trial by Adenis, A., Blay, J.-Y., Bui-Nguyen, B., Bouché, O., Bertucci, F., Isambert, N., Bompas, E., Chaigneau, L., Domont, J., Ray-Coquard, I., Blésius, A., Van Tine, B.A., Bulusu, V.R., Dubreuil, P., Mansfield, C.D., Acin, Y., Moussy, A., Hermine, O., Le Cesne, A.

“…Masitinib is a highly selective tyrosine kinase inhibitor with activity against the main oncogenic drivers of gastrointestinal stromal tumor (GIST). Masitinib…”
Get full text

Efficacy of trabectedin in malignant solitary fibrous tumors: a retrospective analysis from the French Sarcoma Group by Khalifa, J, Ouali, M, Chaltiel, L, Le Guellec, S, Le Cesne, A, Blay, J-Y, Cousin, P, Chaigneau, L, Bompas, E, Piperno-Neumann, S, Bui-Nguyen, B, Rios, M, Delord, J-P, Penel, N, Chevreau, C

“…Advanced malignant solitary fibrous tumors (SFTs) are rare soft-tissue sarcomas with a poor prognosis. Several treatment options have been reported, but with…”
Get full text

Epithelioid hemangio-endothelioma (EHE) in NETSARC: The nationwide series of 267 patients over 12 years by Blay, JY, Piperno-Neumann, S., Watson, S., Dufresne, A., Valentin, T., Duffaud, F., Toulmonde, M., Italiano, A., Bertucci, F., Tlemsani, C., Firmin, N., Bompas, E., Perrin, C., Ropars, M., Saada-Bouzid, E., Dubray-Longeras, P., Hervieu, A., Lebbe, C., Gantzer, J., Chaigneau, L., Fiorenza, F., Rios, M., Isambert, N., Soibinet, P., Boudou-Roquette, P., Verret, B., Ferron, G., Ryckewaert, T., Lebellec, L., Brahmi, M., Gouin, F., Meeus, P., Vaz, G., Le Loarer, F., Karanian, M., De Pinieux, G., Ducimetiere, F., Chemin, C., Morelle, M., Le Cesne, A., Penel, N.

“…Epithelioid hemangioendothelioma (EHE) is an ultrarare sarcoma whose natural history and treatment is not well defined. We report on the presentation and…”
Get full text

Surgery in reference centers improves survival of sarcoma patients: a nationwide study by Blay, J -Y, Honoré, C, Stoeckle, E, Meeus, P, Jafari, M, Gouin, F, Anract, P, Ferron, G, Rochwerger, A, Ropars, M, Carrere, S, Marchal, F, Sirveaux, F, Di Marco, A, Le Nail, L R, Guiramand, J, Vaz, G, Machiavello, J -C, Marco, O, Causeret, S, Gimbergues, P, Fiorenza, F, Chaigneau, L, Guillemin, F, Guilloit, J -M, Dujardin, F, Spano, J -P, Ruzic, J -C, Michot, A, Soibinet, P, Bompas, E, Chevreau, C, Duffaud, F, Rios, M, Perrin, C, Firmin, N, Bertucci, F, Le Pechoux, C, Le Loarer, F, Collard, O, Karanian-Philippe, M, Brahmi, M, Dufresne, A, Dupré, A, Ducimetière, F, Giraud, A, Pérol, D, Toulmonde, M, Ray-Coquard, I, Italiano, A, Le Cesne, A, Penel, N, Bonvalot, S

Get full text

Sorafenib in patients with progressive malignant solitary fibrous tumors: a subgroup analysis from a phase II study of the French Sarcoma Group (GSF/GETO) by Valentin, T., Fournier, C., Penel, N., Bompas, E., Chaigneau, L., Isambert, N., Chevreau, C.

“…Summary Malignant solitary fibrous tumors are rare soft-tissue sarcomas. They are considered as low-grade malignancies, but may display metastatic potential in…”
Get full text

Humeral metastasis as the only recurrence of a 5-year resected gastrointestinal stromal tumor: a case report by Braunstein, C, Sirveaux, F, Kalbacher, E, Aubry, S, Delroeux, D, Hubert, P, Marie, B, Meynard, G, Mihai, I, Chaigneau, L

“…Gastrointestinal stromal tumors represent the most frequently encountered primary mesenchymal tumors. Whereas the liver and the peritoneum are known to be the…”
Get full text

Prolonged overall survival for patients with bone-only metastases at presentation of metastatic breast cancer by Curtit, E., Bazan, F., Chaigneau, L., Mouillet, G., Dobi, E., Mansi, L., Meneveau, N., Paillard, M.-J., Meynard, G., Klajer, E., Villanueva, C., Montcuquet, P., Pivot, X., Cals, L.

Get full text

A phase II trial to evaluate gefitinib as second- or third-line treatment in patients with recurring locoregionally advanced or metastatic cervical cancer by Goncalves, A, Fabbro, M, Lhommé, C, Gladieff, L, Extra, J.-M, Floquet, A, Chaigneau, L, Carrasco, A. Tisseron, Viens, P

“…Abstract Background. Cancer of the cervix occurs in ∼ 500 000 women worldwide each year, with prognosis highly dependent on disease stage at diagnosis…”
Get full text

Conservative surgery vs. duodeneopancreatectomy in primary duodenal gastrointestinal stromal tumors (GIST): A retrospective review of 114 patients from the French Sarcoma Group (FSG) by Duffaud, F, Meeus, P, Bachet, J.B, Cassier, P, Huynh, T.K, Boucher, E, Bouché, O, Moutardier, V, le Cesne, A, Landi, B, Marchal, F, Bay, J.O, Bertucci, F, Spano, J.P, Stoeckle, E, Collard, O, Chaigneau, L, Isambert, N, Lebrun-Ly, V, Mancini, J, Blay, J.Y, Bonvalot, S

“…Abstract Background Duodenal GISTs represent 3–5% of all GISTs with limited understanding of patient outcomes. We conducted a retrospective analysis of primary…”
Get full text

Impact of BRCA status on outcomes and survival in high-risk early breast cancers by Klajer, E., Paget-Bailly, S., Meynard, G., Meurisse, A., Bazan, F., Chaigneau, L., Dobi, E., Meneveau, N., Montcuquet, P., Villanueva, C., Thiery-Vuillemin, A., Kalbacher, E., Populaire, C., Collonge-Rame, M.-A., Gligorov, J., Curtit, E., Pivot, X., Mansi, L.

Get full text

Osteosarcomas of the mandible: multidisciplinary management of a rare tumor of the young adult a cooperative study of the GSF-GETO, Rare Cancer Network, GETTEC/REFCOR and SFCE by Thariat, J., Schouman, T., Brouchet, A., Sarini, J., Miller, R.C., Reychler, H., Ray-Coquard, I., Italiano, A., Verite, C., Sohawon, S., Bompas, E., Dassonville, O., Salas, S., Aldabbagh, K., Maingon, P., de La MotteRouge, T., Kurtz, J.E., Usseglio, J., Kerbrat, P., Raoul, G., Lotz, J.P., Bar-Sela, G., Brugières, L., Chaigneau, L., Saada, E., Odin, G., Marcy, P.Y., Thyss, A., Julieron, M.

“…Mandibular osteosarcomas (MOS) mostly affect young adults. Their treatment is extrapolated from that of extragnathic osteosarcomas. A retrospective…”
Get full text

Correlation between overall survival and growth modulation index in pre-treated sarcoma patients: a study from the French Sarcoma Group by Cousin, S., Blay, J.Y., Bertucci, F., Isambert, N., Italiano, A., Bompas, E., Ray-Coquard, I., Perrot, D., Chaix, M., Bui-Nguyen, B., Chaigneau, L., Corradini, N., Penel, N.

“…Growth modulation index (GMI), the ratio of two times to progression measured in patients receiving two successive treatments (GMI = TTP2/TTP1), has been…”
Get full text

Cisplatin alone or combined with gemcitabine in carcinomas of unknown primary: Results of the randomised GEFCAPI 02 trial by Gross-Goupil, M, Fourcade, A, Blot, E, Penel, N, Négrier, S, Culine, S, Chaigneau, L, Lesimple, T, Priou, F, Lortholary, A, Kaminsky, M.C, Provencal, J, Voog, E, Bouzy, J, Laplanche, A, Fizazi, K

“…Abstract Purpose To compare the overall survival rates of good-prognosis carcinomas of an unknown primary site (CUPS) patients treated with cisplatin alone (C)…”
Get full text

Evaluation of the management of soft tissue sarcomas in Franche-Comté since the establishment of a multidisciplinary meeting at University Hospital. About 47 cases by Haddad, J, Kalbacher, E, Piccard, M, Aubry, S, Chaigneau, L, Pauchot, J

“…A multidisciplinary meeting (RCP) dedicated to the treatment of sarcoma was established in Franche-Comte in 2010. The goals of the study are: (a) To evaluate…”
Get full text

Large surgical resection of a shoulder sarcoma's and secure one stage reconstruction with lattissimi dorsi and serratus anterior flap. Updating about a case by Haddad, J, Gouailler, F, Aleton, E, Chaigneau, L, Pauchot, J

“…The soft tissue sarcomas (STM) are tumors developed at the expense of connective tissue. They are rare and have severe prognosis. The principles of management…”
Get full text

3432 Metronomic cyclophosphamide (MC) treatment for heavily pre-treated metastatic Soft Tissue Sarcoma (mSTS) by Simon, P, Calcagno, F, Klajer, E, Meynard, G, Delroeux, D, Aubry, S, Pauchot, J, Valmary-Degano, S, Nerich, V, Kalbacher, E, Isambert, N, Chaigneau, L

Get full text