Search Results - "Chaidir, Lidya"
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Docking-Based Virtual Screening and Molecular Dynamics Simulations of Quercetin Analogs as Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors of Mycobacterium tuberculosis
Published in Scientia pharmaceutica (01-06-2021)“…The emergence of multidrug-resistant Mycobacterium tuberculosis (MTB) has become a major problem in treating tuberculosis (TB) and shows the need to develop…”
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Evaluation of Xpert MTB-RIF guided diagnosis and treatment of rifampicin-resistant tuberculosis in Indonesia: A retrospective cohort study
Published in PloS one (28-02-2019)“…Rifampicin-resistant tuberculosis (RR-TB) is largely underdetected in Indonesia. Xpert MTB/RIF (Xpert) has recently been introduced, prioritizing patients at…”
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3
The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
Published in PloS one (09-02-2023)“…Ranked second in global tuberculosis (TB) incidence, Indonesia has developed a National Strategy for TB Prevention and Control 2020-2024 to accelerate the TB…”
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4
Reliability of RT-qPCR Pooling Method for COVID-19 Detection in Various Cycle Threshold Values
Published in Althea Medical Journal (30-06-2023)“…Background: Reverse Transcriptase Quantitative Real-time Polymerase Chain Reaction (RT-qPCR) is a standard method to detect SARS-CoV-2, the cause of COVID-19…”
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5
Are neighbourhoods of tuberculosis cases a high-risk population for active intervention? A protocol for tuberculosis active case finding
Published in PloS one (13-08-2021)“…Indonesia has the second largest tuberculosis (TB) burden globally. Attempts to scale-up TB control efforts have focused on TB households. However, in most…”
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Transcriptional biomarkers for treatment monitoring of pulmonary drug-resistant tuberculosis: Protocol for a prospective observational study in Indonesia
Published in Tropical medicine and infectious disease (01-11-2022)“…Many blood-based gene expression biomarkers for monitoring tuberculosis (TB) treatment have been suggested so far, but promising biomarker results for…”
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Evaluation of a real-time PCR assay performance to detect Mycobacterium tuberculosis , rifampicin, and isoniazid resistance in sputum specimens: a multicenter study in two major cities of Indonesia
Published in Frontiers in microbiology (10-05-2024)“…Tuberculosis (TB) is one of the major global health issues due to its high mortality rate, especially in low- and middle-income countries. One of the key…”
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Viability Test of Mycobacterium Tuberculosis Bacteria Stored in Various Cryopreservation Periods
Published in Althea Medical Journal (30-03-2024)“…Background: The specimen storage room serves as bioarchive for prospective research purposes. Cryopreservation or preservation at very low temperatures has…”
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Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis
Published in BMC genomics (05-02-2018)“…Meningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM);…”
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Discovery of potent triterpenoid and limonoid compounds targeting Mycobacterium tuberculosis enoyl acyl carrier protein reductase (InhA): An in silico investigation
Published in Informatics in medicine unlocked (2023)“…Drug resistance remains one of the primary concerns in treating tuberculosis (TB), making it imperative to find new and effective drug candidates for improved…”
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Microbiological Testing of Gastric Aspirate Improves the Diagnosis of Pulmonary Tuberculosis in Unconscious Adults with TB Meningitis
Published in Infectious disease reports (20-12-2020)“…Conventional sputum collection for TB diagnosis is difficult in TB meningitis patients since most of them are admitted with decreased consciousness. It is…”
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12
Application of Replicate Organism Detection and Counting Method (RODAC) in Measuring Mycobacterium Tuberculosis Contamination in High Burden Laboratories
Published in Althea Medical Journal (31-12-2022)“…Background: Technicians working in high burden tuberculosis (TB) laboratories pose a higher risk of being infected by Mycobacterium tuberculosis from clinical…”
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The Role of Amino Acids in Tuberculosis Infection: A Literature Review
Published in Metabolites (30-09-2022)“…Recently, there was an abundance of studies being conducted on the metabolomic profiling of tuberculosis patients. Amino acids are critical metabolites for the…”
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Comparison of real time IS6110-PCR, microscopy, and culture for diagnosis of tuberculous meningitis in a cohort of adult patients in Indonesia
Published in PloS one (21-12-2012)“…Bacteriological confirmation of tuberculous (TB) meningitis is difficult. Culture is slow and microscopy has insufficient sensitivity. We evaluated real time…”
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Effective Visual Media to Increase Knowledge and Comprehension of Multidrug Resistant Tuberculosis Among Patients and Their Caregivers
Published in Majalah kedokteran Bandung (01-06-2023)“…Indonesia ranks thirdamong countries with the largest number of TB cases after India and China. Globally, more than 3-4% of all TB cases are…”
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Comparison of Interpretation between Pyrosequencing and Xpert MTB/RIF Assay in Multidrug-Resistant Tuberculosis
Published in Majalah kedokteran Bandung (01-12-2020)“…Indonesia is one of the countries with the highest multidrug-resistant tuberculosis cases in the world. Rapid molecular test using the Xpert MTB/RIF assay is…”
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Positivity Rate of Pyrosequencing to Diagnose Drug-Resistant Tuberculosis Directly from Sputum with Different Bacterial Load
Published in The Indonesian biomedical journal (01-12-2020)“…BACKGROUND: Molecular techniques, which detect mutations associated with drug resistance tuberculosis (TB), are promising technologies for rapid diagnosis and…”
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18
Development of Nucleic Acid Lateral Flow Immunoassay for Rapid and Accurate Detection of Chikungunya Virus in Indonesia
Published in Journal of microbiology and biotechnology (28-12-2021)“…Chikungunya fever is an arboviral disease caused by the virus (CHIKV). The disease has similar clinical manifestations with other acute febrile illnesses which…”
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Implementation of LED fluorescence microscopy for diagnosis of pulmonary and HIV-associated tuberculosis in a hospital setting in Indonesia
Published in PloS one (19-04-2013)“…Fluorescence microscopy (FM) has not been implemented widely in TB endemic settings and little evaluation has been done in HIV-infected patients. We evaluated…”
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Correction: The effect of M. tuberculosis lineage on clinical phenotype
Published in PLOS global public health (2024)“…[This corrects the article DOI: 10.1371/journal.pgph.0001788.]…”
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