Search Results - "Chai, Xuejun"
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Effect of Heat Stress on Hippocampal Neurogenesis: Insights into the Cellular and Molecular Basis of Neuroinflammation-Induced Deficits
Published in Cellular and molecular neurobiology (01-01-2023)“…Heat stress is known to result in neuroinflammation, neuronal damage, and disabilities in learning and memory in animals and humans. It has previously been…”
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Reelin Signaling Inactivates Cofilin to Stabilize the Cytoskeleton of Migrating Cortical Neurons
Published in Frontiers in cellular neuroscience (23-05-2017)“…Neurons are highly polarized cells. They give rise to several dendrites but only one axon. In addition, many neurons show a preferred orientation. For example,…”
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Reelin Stabilizes the Actin Cytoskeleton of Neuronal Processes by Inducing n-Cofilin Phosphorylation at Serine3
Published in The Journal of neuroscience (07-01-2009)“…The extracellular matrix protein Reelin, secreted by Cajal-Retzius cells in the marginal zone of the cortex, controls the radial migration of cortical neurons…”
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Reelin Induces Branching of Neurons and Radial Glial Cells during Corticogenesis
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2015)“…Newborn neurons migrate along the processes of radial glial cells (RGCs) to reach their final positions in the cortex. Here, we visualized individual migrating…”
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β-Hydroxybutyrate Alleviates Low Glucose–Induced Apoptosis via Modulation of ROS-Mediated p38 MAPK Signaling
Published in Journal of molecular neuroscience (01-05-2022)“…Hypoglycemia has emerged as a prominent complication in anti-diabetic drug therapy or negative energy balance of animals, which causes brain damage, cognitive…”
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Emerging topics in Reelin function
Published in The European journal of neuroscience (01-05-2010)“…Reelin signalling in the early developing cortex regulates radial migration of cortical neurons. Later in development, Reelin promotes maturation of dendrites…”
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Capture of activity-induced ultrastructural changes at synapses by high-pressure freezing of brain tissue
Published in Nature protocols (01-06-2014)“…This Protocol provides directions on using high-pressure freezing to prepare tissue samples for electron microscopy, avoiding the need for aldehyde fixation…”
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Profile of MIF in Developing Hippocampus: Association With Cell Proliferation and Neurite Outgrowth
Published in Frontiers in molecular neuroscience (12-08-2020)“…Proinflammatory cytokine macrophage migration inhibitory factor (MIF) is a multi-functional cytokine and has been found involved in many neurological diseases…”
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High-fat diet-disturbed gut microbiota-colonocyte interactions contribute to dysregulating peripheral tryptophan-kynurenine metabolism
Published in Microbiome (19-07-2023)“…Aberrant tryptophan (Trp)-kynurenine (Kyn) metabolism has been implicated in the pathogenesis of human disease. In particular, populations with long-term…”
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Use of Environmental DNA to Evaluate the Spatial Distribution of False Kelpfish (Sebastiscus marmoratus) in Nearshore Areas of Gouqi Island
Published in Fishes (01-10-2024)“…This study aims to explore the spatial distribution of false kelpfish (Sebastiscus marmoratus) in the mussel farming area, artificial reef areas of Gouqi…”
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Trajectory Analysis Unveils Reelin's Role in the Directed Migration of Granule Cells in the Dentate Gyrus
Published in The Journal of neuroscience (03-01-2018)“…Reelin controls neuronal migration and layer formation. Previous studies in mice deficient in Reelin focused on the result of the developmental process in…”
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Reelin and cofilin cooperate during the migration of cortical neurons: a quantitative morphological analysis
Published in Development (Cambridge) (15-03-2016)“…In reeler mutant mice, which are deficient in reelin (Reln), the lamination of the cerebral cortex is disrupted. Reelin signaling induces phosphorylation of…”
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Dietary Protein Requirement of Juvenile Dotted Gizzard Shad Konosirus punctatus Based on the Variation of Fish Meal
Published in Animals (Basel) (22-02-2023)“…An 8-week feeding trial was conducted to investigate the effects of dietary protein levels on growth performance, feed utilization, and energy retention of…”
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Dietary Supplementation With Acer truncatum Oil Promotes Remyelination in a Mouse Model of Multiple Sclerosis
Published in Frontiers in neuroscience (02-05-2022)“…Multiple sclerosis is a chronic demyelinating disease of uncertain etiology. Traditional treatment methods produce more adverse effects. Epidemiological and…”
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Unbalanced diets enhance the complexity of gut microbial network but destabilize its stability and resistance
Published in Stress biology (27-06-2023)“…Stability is a fundamental ecological property of the gut microbiota and is associated with host health. Numerous studies have shown that unbalanced dietary…”
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Disparities in Body Color Adaptability and Ambient Light Color Preference between Wild and Hatchery-Reared Marbled Rockfish ( Sebastiscus marmoratus )
Published in Animals (Basel) (05-06-2024)“…Hatchery rearing significantly influences the phenotypic development of fish, with potential adverse effects for the post-release performance of…”
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Characterization of the complete mitochondrial genome sequence of Nibea diacanthus and its phylogenetic implication
Published in Mitochondrial DNA. Part B. Resources (14-01-2020)“…The blackspotted croaker (Nibea diacanthus) is an important food fish of Indo-West Pacific and China. To study the phylogenetic status, we sequenced the…”
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Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing
Published in Journal of comparative neurology (1911) (01-08-2012)“…Despite recent progress in fluorescence microscopy techniques, electron microscopy (EM) is still superior in the simultaneous analysis of all tissue components…”
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β-Hydroxybutyric acid improves cognitive function in a model of heat stress by promoting adult hippocampal neurogenesis
Published in Stress biology (29-12-2022)“…Heat stress has multiple potential effects on the brain, such as neuroinflammation, neurogenesis defects, and cognitive impairment. β-hydroxybutyric acid…”
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Differences in External Morphology, Body Composition and Swimming Performance Between Hatchery- and Wild-Origin Marbled Rockfish (Sebastiscus marmoratus)
Published in Frontiers in Marine Science (16-06-2022)“…Stock enhancement based on hatchery-reared fish has become one of the most common forms of management practices in marine fisheries resource restoration…”
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