Search Results - "Chai, Wenxia"

Structural Abnormalities of the Inferoseptal Left Ventricular Wall Detected by Cardiac Magnetic Resonance Imaging in Carriers of Hypertrophic Cardiomyopathy Mutations by Germans, Tjeerd, Wilde, Arthur A.M., Dijkmans, Pieter A., Chai, Wenxia, Kamp, Otto, Pinto, Yigal M., van Rossum, Albert C.

“…Structural Abnormalities of the Inferoseptal Left Ventricular Wall Detected by Cardiac Magnetic Resonance Imaging in Carriers of Hypertrophic Cardiomyopathy…”
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The role of calcitonin gene-related peptide (CGRP) in ischemic preconditioning in isolated rat hearts by Chai, Wenxia, Mehrotra, Suneet, Jan Danser, A.H., Schoemaker, Regien G.

“…Brief coronary artery occlusion can protect the heart against damage during subsequent prolonged coronary artery occlusion; ischemic preconditioning. The role…”
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Nongenomic Effects of Aldosterone in the Human Heart: Interaction With Angiotensin II by Chai, Wenxia, Garrelds, Ingrid M, de Vries, René, Batenburg, Wendy W, van Kats, Jorge P, Danser, A H. Jan

“…Aldosterone exerts rapid “nongenomic” effects in various nonrenal tissues. Here, we investigated whether such effects occur in the human heart. Trabeculae and…”
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Mast cell degranulation mediates bronchoconstriction via serotonin and not via renin release by Krop, Manne, Özünal, Zeynep G., Chai, Wenxia, de Vries, René, Fekkes, Durk, Bouhuizen, Angelique M., Garrelds, Ingrid M., Danser, A.H. Jan

“…To verify the recently proposed concept that mast cell-derived renin facilitates angiotensin II-induced bronchoconstriction bronchial rings from male…”
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Cardioprotective Effects of Eplerenone in the Rat Heart: Interaction With Locally Synthesized or Blood-Derived Aldosterone? by Chai, Wenxia, Garrelds, Ingrid M, de Vries, René, Jan Danser, A H

“…Mineralocorticoid receptor antagonism with eplerenone reduces mortality in heart failure, possibly because of blockade of the deleterious effects of…”
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Genomic and nongenomic effects of aldosterone in the rat heart: why is spironolactone cardioprotective? by Chai, Wenxia, Garrelds, Ingrid M, Arulmani, Udayasankar, Schoemaker, Regien G, Lamers, Jos M J, Danser, A H Jan

“…1 Mineralocorticoid receptor (MR) antagonism with spironolactone reduces mortality in heart failure on top of ACE inhibition. To investigate the underlying…”
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Adrenal Angiotensin: Origin and Site of Generation by van Kats, Jorge P., Chai, Wenxia, Duncker, Dirk J., Schalekamp, Maarten A.D.H., Danser, A.H. Jan

“…Circulating angiotensin (Ang) II accumulates in adrenal tissue via binding to Ang II type 1 (AT 1) receptors, reaching levels that are 15 to 20 times higher…”
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Steroidogenesis vs. steroid uptake in the heart: do corticosteroids mediate effects via cardiac mineralocorticoid receptors? by WENXIA CHAI, HOFLAND, Johannes, JANSEN, Pieter M, GARRELDS, Ingrid M, DE VRIES, René, VAN DEN BOGAERDT, Antoon J, FEELDERS, Richard A, DE JONG, Frank H, JAN DANSER, A. H

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Cobalt-nitrogen-doped ordered macro-/mesoporous carbon for highly efficient oxygen reduction reaction by Sun, Tingting, Xu, Lianbin, Li, Shengyu, Chai, Wenxia, Huang, Yan, Yan, Yushan, Chen, Jianfeng

“…[Display omitted] •Co-N-doped ordered macro-/mesoporous carbons are prepared by dual-templating method.•ORR activity relates to the content of doped…”
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Cardiac aldosterone in subjects with hypertrophic cardiomyopathy by Wenxia Chai, Hoedemaekers, Yvonne M, van Schaik, Ron HN, van Fessem, Marianne, Garrelds, Ingrid M, Saris, Jasper J, Dooijes, Dennis, ten Cate, Folkert J, Kofflard, Marcel MJ, Danser, AH Jan

“…Left ventricular (LV) hypertrophy in subjects with hypertrophic cardiomyopathy (HCM) is variable, suggesting a role for modifying factors. Here, we determined…”
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Why are mineralocorticoid receptor antagonists cardioprotective? by Chai, Wenxia, Danser, A H Jan

“…Two clinical trials, the Randomized ALdosterone Evaluation Study (RALES) and the EPlerenone HEart failure and SUrvival Study (EPHESUS), have recently shown…”
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Steroidogenesis vs. steroid uptake in the heart: do corticosteroids mediate effects via cardiac mineralocorticoid receptors? by Chai, Wenxia, Hofland, Johannes, Jansen, Pieter M, Garrelds, Ingrid M, de Vries, René, van den Bogaerdt, Antoon J, Feelders, Richard A, de Jong, Frank H, Danser, AH Jan

“…OBJECTIVETo test whether glucocorticoids act as the endogenous agonist of cardiac mineralocorticoid receptors, we evaluated the cardiac effects of aldosterone…”
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Cardioprotective effects of eplerenone in the rat heart: interaction with locally synthesized or blood‐derived aldosterone? by Danser, Alexander HJ, Chai, Wenxia

“…Mineralocorticoid receptor (MR) antagonism with eplerenone reduces mortality in heart failure, possibly due to blockade of the deleterious effects of cardiac…”
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Inotropic effects of prokinetic agents with 5-HT4 receptor agonist actions on human isolated myocardial trabeculae by Chai, Wenxia, Chan, Kayi Y., de Vries, René, van den Bogeardt, Antoon J., de Maeyer, Joris H., Schuurkes, Jan A.J., Villalón, Carlos M., Saxena, Pramod R., Danser, A.H. Jan, MaassenVanDenBrink, Antoinette

“…Besides acting as gastrointestinal prokinetic agents, 5-hydroxytryptamine4 (5-HT4) receptor agonists can induce positive inotropism in human isolated atrium,…”
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Is angiotensin II made inside or outside of the cell? by Chai, Wenxia, Danser, A H Jan

“…Angiotensin synthesis at tissue sites is well-established, and depends largely, if not completely, on kidney-derived renin. The exact tissue site of…”
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Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae by Chai, Wenxia, Chan, Kayi Y, de Vries, René, van den Bogeardt, Antoon J, de Maeyer, Joris H, Schuurkes, Jan A J, Villalón, Carlos M, Saxena, Pramod R, Danser, A H Jan, MaassenVanDenBrink, Antoinette

“…Besides acting as gastrointestinal prokinetic agents, 5-hydroxytryptamine(4) (5-HT(4)) receptor agonists can induce positive inotropism in human isolated…”
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