Search Results - "Chai, Ming G."

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination by Le, Caroline P., Nowell, Cameron J., Kim-Fuchs, Corina, Botteri, Edoardo, Hiller, Jonathan G., Ismail, Hilmy, Pimentel, Matthew A., Chai, Ming G., Karnezis, Tara, Rotmensz, Nicole, Renne, Giuseppe, Gandini, Sara, Pouton, Colin W., Ferrari, Davide, Möller, Andreas, Stacker, Steven A., Sloan, Erica K.

“…Chronic stress induces signalling from the sympathetic nervous system (SNS) and drives cancer progression, although the pathways of tumour cell dissemination…”
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VEGF-D Promotes Tumor Metastasis by Regulating Prostaglandins Produced by the Collecting Lymphatic Endothelium by Karnezis, Tara, Shayan, Ramin, Caesar, Carol, Roufail, Sally, Harris, Nicole C., Ardipradja, Kathryn, Zhang, You Fang, Williams, Steven P., Farnsworth, Rae H., Chai, Ming G., Rupasinghe, Thusitha W.T., Tull, Dedreia L., Baldwin, Megan E., Sloan, Erica K., Fox, Stephen B., Achen, Marc G., Stacker, Steven A.

“…Lymphatic metastasis is facilitated by lymphangiogenic growth factors VEGF-C and VEGF-D that are secreted by some primary tumors. We identified regulation of…”
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What Are the Current Approaches to Optimising Antimicrobial Dosing in the Intensive Care Unit? by Chai, Ming G., Cotta, Menino O., Abdul-Aziz, Mohd H., Roberts, Jason A.

“…Antimicrobial dosing in the intensive care unit (ICU) can be problematic due to various challenges including unique physiological changes observed in…”
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Beta-Lactam Dose Optimisation in the Intensive Care Unit: Targets, Therapeutic Drug Monitoring and Toxicity by Legg, Amy, Carmichael, Sinead, Chai, Ming G, Roberts, Jason A, Cotta, Menino O

“…Beta-lactams are an important family of antibiotics used to treat infections and are commonly used in critically ill patients. Optimal use of these drugs in…”
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Accuracy of a precision dosing software program for predicting antibiotic concentrations in critically ill patients by Chai, Ming G, Roberts, Jason A, Farkas, Andras, Cotta, Menino O

“…Critically ill patients with sepsis are predisposed to physiological changes that can reduce the probability of achieving target antibiotic exposures…”
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Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs by Jager, Nynke G.L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A., Cotta, Menino O.

“…Precision dosing programs are promising tools for optimising antimicrobial dosing. Selecting the ideal program for local application may be challenging due to…”
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Factors Influencing Integration and Usability of Model-Informed Precision Dosing Software in the Intensive Care Unit by Chai, Ming G, Roberts, Natasha A, Dobbins, Chelsea, Roberts, Jason A, Cotta, Menino O

“…Antimicrobial dosing in critically ill patients is challenging and model-informed precision dosing (MIPD) software may be used to optimize dosing in these…”
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Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis by Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A., Irwin, Adam D.

“…Purpose Early recognition and effective treatment of sepsis improves outcomes in critically ill patients. However, antibiotic exposures are frequently…”
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Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis by Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A., Irwin, Adam D.

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Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study by Chai, Ming G., Roberts, Jason A., Kelly, Christina F., Ungerer, Jacobus P.J., McWhinney, Brett C., Lipman, Jeffrey, Farkas, Andras, Cotta, Menino O.

“…Broad-spectrum antibiotics such as beta-lactams and vancomycin are frequently used to treat critically ill patients, however, a significant number do not…”
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Bioluminescent orthotopic model of pancreatic cancer progression by Chai, Ming G, Kim-Fuchs, Corina, Angst, Eliane, Sloan, Erica K

“…Pancreatic cancer has an extremely poor five-year survival rate of 4-6%. New therapeutic options are critically needed and depend on improved understanding of…”
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Abstract A7: Neural regulation of metastasis: New avenues for therapeutic intervention by Le, Caroline P., Lamkin, Donald, Chai, Ming G., Kim, Corina, Pimentel, Matthew A., Cole, Steven W., Sloan, Erica K.

“…Abstract Recent clinical and experimental studies demonstrated that the neuroendocrine system accelerates cancer development and progression. To investigate…”
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Abstract A113: Chronic stress promotes lymph node metastasis through beta-adrenergic regulation of lymphangiogenesis by Le, Caroline P., Pimentel, Matthew A., Kim, Corina, Nowell, Cameron J., Karnezis, Tara, Chai, Ming G., Herald, Marco, Stacker, Steven A., Sloan, Erica K.

“…Abstract Lymphangiogenesis drives breast cancer metastasis to lymph nodes. However, the physiological pathways that regulate lymphangiogenesis and lymph node…”
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Bioluminescent Orthotopic Model of Pancreatic Cancer Progression by Chai, Ming G., Kim-Fuchs, Corina, Angst, Eliane, Sloan, Erica K.

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