Search Results - "Chahl, L A"

Hydrogen sulphide: an endogenous stimulant of capsaicin‐sensitive primary afferent neurons? by Chahl, L A

“…Hydrogen sulphide (H2S) is a gas best known for its rotten egg smell. The toxic effects of high concentrations of H2S have been extensively investigated. It is…”
Get full text

Distribution of Fos-like immunoreactivity in guinea-pig brain following administration of the neurokinin-1 receptor agonist, [Sar 9,Met(O 2) 11]substance P by Yip, J., Chahl, L.A.

“…The tachykinins are a family of peptides with putative neurotransmitter roles in the nervous system. They mediate their effects via neurokinin-1, neurokinin-2…”
Get full text

Induction of fos-like immunoreactivity by opioids in guinea-pig brain by Bot, G., Chahl, L.A.

“…In the present study the effects of intracerebroventricular (i.c.v.) administration of 100 nmol of morphine, the selective μ-receptor agonist DAMGO, the…”
Get full text

Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex by TOONEY, P. A, AU, G. G, CHAHL, L. A

“…The distribution of tachykinin NK(1) and NK(3) receptors in the prefrontal (Brodmann area 9) and visual cortex (Brodmann area 17) of formalin-fixed postmortem…”
Get full text

Antidromic vasodilatation and neurogenic inflammation by Chahl, L A

Get more information

Fos-like immunoreactivity in tyrosine hydroxylase and substance P-like immunoreactive neurones in guinea-pig brain following intracerebroventricular injection of morphine and U50,488H by Bot, G., Chahl, L. A.

“…Opioid drugs such as morphine have powerful reinforcing effects which lead to drug‐seeking behaviour. Both dopamine‐ and substance P‐containing neurones have…”
Get full text

Localization of NK1 and NK3 receptors in guinea-pig brain by YIP, Jane, CHAHL, Loris A

“…In this study the localizations of tachykinin neurokinin-1 (NK1) and neurokinin-3 (NK3) receptors in the guinea-pig brain are described. In agreement with…”
Get full text

Effects of putative neurotransmitters and related drugs on withdrawal contractures of guinea‐pig isolated ileum following brief contact with [Met5] enkephalin by Chahl, Loris A.

“…1 Brief exposure for 2 min of guinea‐pig isolated ileum to [Met5]enkephalin (MEnk) and noradrenaline has been shown previously to produce withdrawal…”
Get full text

Effects of intracerebroventricularly administered mu-, delta- and kappa-opioid agonists on locomotor activity of the guinea pig and the pharmacology of the locomotor response to U50,488H by Bot, G, Chahl, L A, Brent, P J, Johnston, P A

“…The effects of intracerebroventricular administration of morphine, the selective mu-agonist DAMGO, the delta-agonist DPDPE, the kappa-preferring peptide…”
Get more information

Distribution of c-Fos in guinea-pig brain following morphine withdrawal by Chahl, L.A., Leah, J., Herdegen, T., Trueman, L., Lynch-Frame, A.M.

“…The distribution of the immediate-early gene and transcription factor protein, c-Fos, was examined in the brains of guinea-pigs following treatment with…”
Get full text

Distribution of substance P-like immunoreactivity in guinea pig central nervous system by Gallagher, A W, Chahl, L A, Lynch, A M

“…The distribution of substance P-like immunoreactivity (SP-LI) in the guinea pig brain has been studied by immunohistochemistry and the results compared with…”
Get more information

The effects of ruthenium red on the response of guinea-pig ileum to capsaicin by Chahl, L A

“…Ruthenium red has recently been found to inhibit the effects of capsaicin on peripheral terminals of sensory neurones. Thus the effects of ruthenium red on the…”
Get more information

The properties of the clonidine withdrawal response of guinea‐pig isolated ileum by Chahl, Loris A.

“…1 The dependence‐inducing effects of clonidine were investigated on the guinea‐pig isolated ileum. Clonidine produced relaxation of the ileum with a threshold…”
Get full text

Withdrawal responses of guinea-pig isolated ileum following brief exposure to opiates and opioid peptides by CHAHL, L. A

“…Withdrawal contractures following brief exposure of guinea-pig ileum to enkephalin analogues, dynorphin A-(1-13) and beta-endorphin and the opiate drugs…”
Get full text

Morphine produces release of substance P-like immunoreactivity from guinea-pig central nervous system by Chahl, L A

“…Recent evidence suggests that opioids might have excitatory as well as inhibitory actions on neurones. Since substance P (SP) has been implicated in opioid…”
Get more information

Increased plasma catecholamines and locomotor activity induced by centrally administered substance P in guinea-pigs by Brent, P J, Johnston, P A, Chahl, L A

“…The effects on locomotor activity and plasma catecholamines of substance P, 0.5 nmol, injected into each lateral ventricle (i.c.v.), or 1 nmol, injected into…”
Get more information

Effects of pertussis toxin on behavioural responses of guinea-pigs to centrally administered substance P, quinpirole, carbachol, U-50,488H, morphine and morphine withdrawal by Bot, G, Chahl, L A

“…The effects of pretreatment with pertussis toxin (PTX) on the sedative effect of morphine administered i.c.v. (200 nmol), and on the locomotor and behavioural…”
Get more information

Tachykinin antagonists inhibit the morphine withdrawal response in guinea-pigs by JOHNSTON, P. A, CHAHL, L. A

“…This study was an investigation of the effects of the tachykinin antagonists, spantide and (D-Pro4, D-Trp7,9,10)substance P 4-11, injected…”
Get full text

Chronic treatment with ascorbic acid inhibits the morphine withdrawal response in guinea-pigs by Johnston, P A, Chahl, L A

“…The effects of ascorbic acid (AA) were investigated on the morphine withdrawal response of guinea-pigs, a species which shares with man the inability to…”
Get more information

The kappa-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs by Brent, P J, Chahl, L A, Cantarell, P A, Kavanagh, C

“…The present study was undertaken to determine whether acute physical dependence occurred in guinea-pigs in vivo and guinea-pig isolated ileum following a…”
Get more information