Search Results - "Chahal, Gurdeep"

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  1. 1

    The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin by Chahal, Gurdeep, Thorpe, Michael, Hellman, Lars

    Published in PloS one (25-06-2015)
    “…Thrombin is a serine protease of the chymotrypsin family that acts both as a procoagulant and as an anticoagulant by cleaving either factor VIII, factor V and…”
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    Journal Article
  2. 2

    Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity by Fu, Zhirong, Akula, Srinivas, Qiao, Chang, Ryu, Jinhye, Chahal, Gurdeep, de Garavilla, Lawrence, Kervinen, Jukka, Thorpe, Michael, Hellman, Lars

    Published in PloS one (28-05-2021)
    “…Ruminants have a very complex digestive system adapted for the digestion of cellulose rich food. Gene duplications have been central in the process of adapting…”
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  3. 3

    Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability by Fu, Zhirong, Thorpe, Michael, Akula, Srinivas, Chahal, Gurdeep, Hellman, Lars T

    Published in Frontiers in immunology (16-10-2018)
    “…Serine proteases are major granule constituents of several of the human hematopoietic cell lineages. Four proteolytically active such proteases have been…”
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  4. 4

    Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities by Thorpe, Michael, Fu, Zhirong, Chahal, Gurdeep, Akula, Srinivas, Kervinen, Jukka, de Garavilla, Lawrence, Hellman, Lars

    Published in PloS one (13-04-2018)
    “…Human neutrophils express at least four active serine proteases, cathepsin G, N-elastase, proteinase 3 and neutrophil serine protease 4 (NSP4). They have all…”
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  6. 6

    Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains by Chahal, Gurdeep, Quintana-Hayashi, Macarena P., Gaytán, Meztlli O., Benktander, John, Padra, Medea, King, Samantha J., Linden, Sara K.

    “…Streptococcus oralis is an oral commensal and opportunistic pathogen that can enter the bloodstream and cause bacteremia and infective endocarditis. Here, we…”
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  7. 7

    Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues by Fu, Zhirong, Akula, Srinivas, Thorpe, Michael, Chahal, Gurdeep, de Garavilla, Lawrence, Kervinen, Jukka, Hellman, Lars

    Published in Developmental and comparative immunology (01-03-2019)
    “…Serine proteases constitute the major protein content of mammalian mast cell granules and the selectivity for substrates by these proteases is of major…”
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