Search Results - "Chaganti, S."

Microbial community day-to-day dynamics during a spring algal bloom event in a tributary of Three Gorges Reservoir by Tan, Bingyuan, Hu, Pengfei, Niu, Xiaoxu, Zhang, Xing, Liu, Jiakun, Frenken, Thijs, Hamilton, Paul B., Haffner, G. Douglas, Chaganti, S. Rao, Nwankwegu, Amechi S., Zhang, Lei

“…The microbial food-loop is critical to energy flow in aquatic food webs. We tested the hypothesis that species composition and relative abundance in a…”
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Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition by Cavallo, Francesca, Graziani, Grazia, Antinozzi, Cristina, Feldman, Darren R, Houldsworth, Jane, Bosl, George J, Chaganti, Raju S K, Moynahan, Mary Ellen, Jasin, Maria, Barchi, Marco

“…Testicular Germ Cell Tumors (TGCT) and patient-derived cell lines are extremely sensitive to cisplatin and other interstrand cross-link (ICL) inducing agents…”
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Diffuse large B cell lymphoma (DLBCL) in patients older than 65 years: analysis of 3 year Real World data of practice patterns and outcomes in England by Hounsome, L., Eyre, T. A., Ireland, R., Hodson, A., Walewska, R., Ardeshna, K., Chaganti, S., McKay, P., Davies, A., Fox, C. P., Kalakonda, N., Fields, P. A.

“…Background We wished to examine treatment and outcome patterns in older diffuse large B-cell lymphoma (DLBCL) patients, with a focus on the effect of…”
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Brentuximab a novel antibody therapy: real‐world use confirms efficacy and tolerability for CD30‐positive cutaneous lymphoma by Engelina, S., Saggu, M., Yoo, J., Shah, F., Stevens, A., Irwin, C., Chaganti, S., Scarisbrick, J.J.

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CAR T in patients with large B‐cell lymphoma not fit for autologous transplant by Kuhnl, A., Kirkwood, A. A., Roddie, C., Menne, T., Tholouli, E., Bloor, A., Besley, C., Chaganti, S., Osborne, W., Norman, J., Gibb, A., Sharplin, K., Cuadrado, M., Correia de Farias, M., Cheok, K., Neill, L., Latif, A. L., González Arias, C., Uttenthal, B., Jones, C., Johnson, R., McMillan, A., Sanderson, R., Townsend, W.

“…Summary Large B‐cell lymphoma (LBCL) patients with comorbidities and/or advanced age are increasingly considered for treatment with CD19 CAR T, but data on the…”
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Neutrophil chemokines secreted by tumor cells mount a lung antimetastatic response during renal cell carcinoma progression by López-Lago, M A, Posner, S, Thodima, V J, Molina, A M, Motzer, R J, Chaganti, R S K

“…The mechanism by which renal cell carcinoma (RCC) colonizes the lung microenvironment during metastasis remains largely unknown. To investigate this process,…”
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Evaluation of haematopoietic stem cell transplantation in patients diagnosed with cutaneous T‐cell lymphoma at a tertiary care centre: should we avoid chemotherapy in conditioning regimes? by Ritchie, S., Qureshi, I., Molloy, K., Yoo, J., Shah, F., Stevens, A., Irwin, C., Chaganti, S., Scarisbrick, J.J.

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Improved outcomes of large B‐cell lymphoma patients treated with CD19 CAR T in the UK over time by Boyle, S., Roddie, C., O'Reilly, M., Menne, T., Norman, J., Gibb, A., Lugthart, S., Chaganti, S., Gonzalez Arias, C., Jones, C., Latif, A., Uttenthal, B. J., Seymour, F., Osborne, W., Springell, D., Hardefeldt, P., Yallop, D., Thoulouli, E., Bloor, A., Besley, C., Mathew, A., Burns, D., Cwynarski, K., Sanderson, R., Kuhnl, A.

“…Summary The success of CD19 Chimeric antigen receptor (CAR) T‐cell therapy in large B‐cell lymphoma (LBCL) has been partially offset by toxicity and logistical…”
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What do we know about Late Onset Huntington's Disease? by Chaganti, Sai S, McCusker, Elizabeth A, Loy, Clement T

“…Although the typical age of onset for Huntington's disease (HD) is in the fourth decade, between 4.4-11.5% of individuals with HD have a late onset (over 60…”
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Outcome and feasibility of radiotherapy bridging in large B‐cell lymphoma patients receiving CD19 CAR T in the UK by Kuhnl, A., Roddie, C., Kirkwood, A. A., Chaganti, S., Norman, J., Lugthart, S., Osborne, W., Gibb, A., Gonzalez Arias, C., Latif, A., Uttenthal, B., Seymour, F., Jones, C., Springell, D., Brady, J. L., Illidge, T., Stevens, A., Alexander, E., Hawley, L., O'Rourke, N., Bedi, C., Prestwich, R., Frew, J., Burns, D., O'Reilly, M., Sanderson, R., Sivabalasingham, S., Mikhaeel, N. G.

“…Summary Radiotherapy (RT) has potential synergistic effects with chimeric antigen receptor (CAR) T but is not widely used as bridging therapy due to logistical…”
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Primary cutaneous B‐cell lymphoma: systemic spread is rare while cutaneous relapses and secondary malignancies are frequent by Chan, S.A., Shah, F., Chaganti, S., Stevens, A., Amel‐Kashipaz, R., Vydianath, B., Scarisbrick, J.J.

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Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach by Korkola, James E, Heck, Sandy, Olshen, Adam B, Feldman, Darren R, Reuter, Victor E, Houldsworth, Jane, Bosl, George J, Chaganti, R S K

“…Germ Cell Tumors (GCT) have a high cure rate, but we currently lack the ability to accurately identify the small subset of patients who will die from their…”
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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas by Dalla-Favera, Riccardo, Pasqualucci, Laura, Neumeister, Peter, Goossens, Tina, Nanjangud, Gouri, Chaganti, R. S. K, Küppers, Ralf

“…Genomic instability promotes tumorigenesis and can occur through various mechanisms, including defective segregation of chromosomes or inactivation of DNA…”
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Unmasking mycosis fungoides/Sézary syndrome from preceding or co-existing benign inflammatory dermatoses requiring systemic therapies: patients frequently present with advanced disease and have an aggressive clinical course by Foo, S.H., Shah, F., Chaganti, S., Stevens, A., Scarisbrick, J.J.

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Greatly reduced risk of EBV reactivation in rituximab-experienced recipients of alemtuzumab-conditioned allogeneic HSCT by Burns, D M, Rana, S, Martin, E, Nagra, S, Ward, J, Osman, H, Bell, A I, Moss, P, Russell, N H, Craddock, C F, Fox, C P, Chaganti, S

“…EBV-associated post-transplant lymphoproliferative disease (PTLD) remains an important complication of allogeneic haematopoietic stem cell transplantation…”
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Ethnic-immigrants in founding teams: Effects on prospector strategy and performance in new Internet ventures by Chaganti, Rajeswararao (Raj) S., Watts, Allison D., Chaganti, Radha, Zimmerman-Treichel, Monica

“…We investigated differences in strategy and performance between new Internet ventures with ethnic-immigrant members in the founding team and a matched set of…”
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Novel cost effective full scale mussel shell bioreactors for metal removal and acid neutralization by DiLoreto, Z.A., Weber, P.A., Olds, W., Pope, J., Trumm, D., Chaganti, S.R., Heath, D.D., Weisener, C.G.

“…Acid mine drainage (AMD) impacted waters are a worldwide concern for the mining industry and countries dealing with this issue; both active and passive…”
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Outcomes in patients with EBV+ PTLD treated with allogeneic EBV‐specific T‐cell immunotherapy (tabelecleucel) under an expanded access program (EAP) in Europe by Choquet, S., Clark, A., Renard, C., Uttenthal, B., Chaganti, S., Trappe, R. U., Comoli, P., Duan, X., Xing, B., Wu, C., Gamelin, L., Terwey, J., Friedetzky, A., Dierickx, D.

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CAR T treatment access and outcomes in patients with large B‐cell lymphoma according to ethnicity and socioeconomic deprivation by Dragoi, D., Cusworth, S., Amrith, M., Sanderson, R., Paneesha, S., Patten, P., Potter, V., Hardefeldt, P., Yallop, D., Chaganti, S., Burns, D., Kuhnl, A.

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Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma by PASQUALUCCI, Laura, MIGLIAZZA, Anna, BASSO, Katia, HOULDSWORTH, Jane, CHAGANTI, R. S. K, DALLA-FAVERA, Riccardo

“…The BCL6 proto-oncogene encodes a transcriptional repressor whose expression is deregulated by chromosomal translocations in approximately 40% of diffuse large…”
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