Search Results - "Chadwick, Joseph"
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Upper thermal limits of growth in brook trout and their relationship to stress physiology
Published in Journal of experimental biology (01-11-2017)“…Despite the threat of climate change, the physiological mechanisms responsible for reduced performance at high temperatures remain unclear for most species…”
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Thermal onset of cellular and endocrine stress responses correspond to ecological limits in brook trout, an iconic cold-water fish
Published in Conservation physiology (2015)“…Laboratory and field experiments were used to establish a temperature threshold for induction of the cellular and endocrine stress responses in brook trout…”
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3
Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial
Published in The Lancet (British edition) (30-06-2018)“…B cells produce alloantibodies and activate alloreactive T cells, negatively affecting kidney transplant survival. By contrast, regulatory B cells are…”
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4
Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma
Published in Cancer cell (10-07-2023)“…For inoperable esophageal adenocarcinoma (EAC), identifying patients likely to benefit from recently approved immunochemotherapy (ICI+CTX) treatments remains a…”
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5
Nuclear receptor coactivators are coexpressed with steroid receptors and regulated by estradiol in mouse brain
Published in Neuroendocrinology (01-07-2011)“…The steroid hormones, including estradiol (E) and progesterone, act in the brain to regulate female reproductive behavior and physiology. These hormones…”
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Steroid Receptor Coactivator-1 from Brain Physically Interacts Differentially with Steroid Receptor Subtypes
Published in Endocrinology (Philadelphia) (01-10-2008)“…In vitro studies reveal that nuclear receptor coactivators enhance the transcriptional activity of steroid receptors, including estrogen (ER) and progestin…”
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“Man Up, Bro!” An Exploration of Masculine Performances in the Outdoor Adventure Field
Published 01-01-2024“…Masculinity is constructed and reinforced through interaction instead of passively internalized (Connell, 2006). The “space” of the outdoors is predominately…”
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Dissertation -
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Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2024)“…Hypoxia signaling influences tumor development through both cell-intrinsic and -extrinsic pathways. Inhibiting hypoxia-inducible factor (HIF) function has…”
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Abstract CT208: High tumor monocyte content predicts long-term survival for patients with operable oesophageal cancer treated with neoadjuvant immunochemotherapy in the LUD2015-005 trial
Published in Cancer research (Chicago, Ill.) (05-04-2024)“…Background: Combined immune checkpoint inhibitors (ICI) with chemotherapy in advanced oesophageal cancer (OC) has shown survival benefit in phase III studies,…”
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Abstract LB131: Association between epigenetic heterogeneity of esophageal adenocarcinoma and response to first-line immunochemotherapy in LUD2015-005 Trial
Published in Cancer research (Chicago, Ill.) (14-04-2023)“…Immune checkpoint inhibitors (ICI) were recently approved as a first-line treatment for inoperable esophageal adenocarcinomas (EAC) in combination with…”
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Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age
Published in GeroScience (20-06-2024)“…Little is known about the possibility of reversing age-related biological changes when they have already occurred. To explore this, we have characterized the…”
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Abstract 1247: Comprehensive molecular profiling to predict first-line immunochemotherapy outcomes in inoperable esophageal adenocarcinoma
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…For patients with inoperable esophageal adenocarcinoma (EAC), prognosis on conventional chemotherapy (CTX) remains poor. In 2021, the FDA approved two αPD-1…”
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Steroid receptor coactivator-2 expression in brain and physical associations with steroid receptors
Published in Neuroscience (01-09-2010)“…Abstract Estradiol and progesterone bind to their respective receptors in the hypothalamus and hippocampus to influence a variety of behavioral and…”
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14
Silence in "The Sisters"
Published in James Joyce quarterly (01-04-1984)Get full text
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15
Violence in Yeat's Later Politics and Poetry
Published in ELH (01-12-1988)Get full text
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Violence in Yeats's Later Politics and Poetry
Published in ELH (01-12-1988)Get full text
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Infinite Jest: Interpretation in Sterne's A Sentimental Journey
Published in Eighteenth-century studies (01-12-1978)Get full text
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Family Romance as National Allegory in Yeats's Cathleen ni Houlihan and The Dreaming of the Bones
Published in Twentieth century literature (01-07-1986)Get full text
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A Blessing and a Curse: The Poetics of Privacy in Tennyson's "The Lady of Shalott"
Published in Victorian poetry (01-04-1986)“…The Lady in "The Lady of Shalott" emblematizes two ideals implicit in both Hallam's notion of the poetry of sensation and in Romantic poetics in general: the…”
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"Crimes Against Fecundity: Joyce and Population Control", by Mary Lowe-Evans (Book Review)
Published in James Joyce Quarterly (01-04-1990)Get full text
Book Review